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III STEP:  FOLLOW-UP

Cohorts were followed for 20 years by means of repeated bi–annual examinations. Loss of cohort was more during the first 14 years (85%) due to incapacitation and migration.

Indirectly, follow-up was carried through the secondary sources i.e. from the Framingham hospital records and town regional mortality registers.

IV STEP:  ANALYSIS

Average annual incidence = 0.0125

R.R. with high cholesterol = 1.81-3.43