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STUDY COHORT includes those women with: 
  1. Natural menopause (1479)     
  2. Hysterectomy + bilateral oopherectomy (3241)

CONTROL COHORT  includes those women with:

  1. Hysterectomy + unilateral 
  2. X-ray & irradiation group

EXCLUDED:

  1. Prior mastectomy
  2. Prior breast cancer
  3. Treated for Pelvic malignancy
  4. Natural menopause <40
  5. Premature removal of ovaries