Parents and guardians should be warned of the risks of young children being taken into malarial endemic areas. Children under 8 years of age can only be offered a limited number of antimalarials for chemoprophylaxis. Chloroquine and primaquine are just a few of the antimalarials which have been shown to be reasonably safe for children. Doxycycline is contraindicated in children less than 8 years, particularly for its effect on permanent teeth. Mefloquine has not yet been generally released for children in every country and may not be registered for children less than 15 kg. Newer drugs such as Malarone could be considered, but again some countries have not registered this drug for use in young children. Some antimalarials such as chloroquine and quinine are cardiotoxic in overdose, so such medications should be kept out of reach of children.