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Enzymology of DNA replication – note that one strand is made continuously and is called the Leading strand, while the other strand needs to be made in pieces (called Okazaki fragments) and is called the lagging strand. One strand needs to be made in pieces because the polymerase can only work by making the new strand in the 5’ to 3’ direction (only works in one direction).

Go to Part II of this lecture

 
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