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  • For conditions which have a cyclical pattern, has the timing of measurements been stated? For example, for blood pressure the timing needed may be time of day, time of week, month and season.
  • Have the precise geographical boundaries of the study been given? If this is not a geographically defined population, can the sampled population be related to a place?
  • Have the populations been defined in terms of their social and economic standing, and geographical and cultural origins?