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front |1 |2 |3 |4 |5 |6 |7 |8 |9 |10 |11 |12 |13 |14 |15 |16 |17 |18 |19 |20 |21 |22 |23 |24 |25 |26 |27 |28 |29 |30 |31 |review |
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Varying cure
rates for each therapy:
1. Flagyl: 84-96% 7 day course 54-62% single dose 2. Cleocin: one clinical trail to date showing 94% cure rate 3. Metrogel: 75-81% 5 day therapy 4. Clindamycin cram: 82-96% 7 day therapy * No significant difference in cure rates between the four therapies therefore each are equally effective. * as many as 30% of women relapse within a month of treatment (more so for topical vs. systemic therapies) and those women with recurrent BV represent a therapeutic challenge. Of note, treatment of male partner does not reduce the recurrence rate. * Only oral systemic treatments found to reduce pregnancy-associated morbidity (ie. PTD). |