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When comparing the relationship of the time in which refineries located in the circuit had been involved to the epidemic curve, the results were evident. Only the refinery dealing with oil containing the chemical markers of derivatives of glycerol was likely to have been involved in the intoxication since the beginning through only two oil batches.

Posada de la Paz M, Philen RM, Schurz HH, et al. Epidemiologic evidence for a new class of compounds associated with Toxic Oil Syndrome. Epidemiology 1999; 10(2): 130-134.