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Micro-sensors and nanotechnology are bringing the ability to detect and monitor disease down to the practical and point-of-care level. The micro-sensors are becoming components in most new devices, reducing in size what was a machine the size of a refrigerator or briefcase to a hand held or embedded system. In addition, these technologies have complete systems integration so that the microsensors can acquire the data, process the information, intelligently store or alert the information, and transmit the information to a belt worn receiver or other data collection device. In the not-too-distant future, micro and nano sensors will be embedded not only in clothing or the home/workplace, but within the body, continuously updating and monitoring health status.