Point-of-care. New devices, especially microsensors, biosensors, handheld or portable imagers, will move out of the hospital or physicians office and into the home and/or workplace. Having these devices will facilitate acquisition of data on a more regular basis and be able to identify trends and monitor the course of disease. Because the technology is enabling smaller devices, the sensors and imagers will eventually be micro-sized and embedded in everything, from appliances to the rooms in our house to our clothing. They will become transparent to the person, updating information in an ubiquitous, non-intrusive manner, thus improving compliance by autonomously monitoring on a continuous basis and informing individuals of changes in a real time manner (rather than once a year or less frequently).