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One of the most important medical issues related to emerging infections is the concern of drug resistance. Examples include strains of gonorrhea, and malarial infections that are now resistant to traditional drugs. Multi-drug-resistant tuberculosis is also a concern. 

Perhaps the primary reason for drug resistance is the 1) inappropriate use of “silver bullets” or antibiotics on the part of the patient (compliance) and 2) over prescription of medications on the part of the physician.