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Most of the practicing clinicians do not have the time to read the literature in their own areas and be up-to-date on new information, be able to critically appraise the literature and its validity and usefulness, without being trained to do so. Fortunately, there are readily available sources that clinicians can turn to, to find the steps mentioned above have been undertaken by experts in the area, and disseminated in a useful format for the use of ordinary practicing clinicians. One such source is the Cochrane Collaboration Library which is a rapidly growing international group of clinicians, methodologists and consumer groups who undertook the task of appraising the literature in various specialties, collating evidence from good quality research and publishing the result in the so-called systematic reviews. Another source is the appearance of a new type of journals, such as the Evidence-Based Medicine Journal and the American College of Physicians’ Journal Club publications. With little effort, in the beginning, most clinicians should be able to utilize these sources to find out clinically important information in the areas of diagnosis, prognosis and therapy. These sources are readily available.