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Effects of endothelium-dependent vasodilators, nitrovasodilators and atriopeptins in rat aorta segments. PLC is phopholipase C; PI, phosphoinositides; DG, diacyglycerol; IP’s, inositol phosphates.

The effects of nitric oxide of EDRF can also be mimicked by atriopeptins which selectively activate particulate guanylyl cyclase.