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Marcus Terentius Varro, in De re rustica libri III (three books on agriculture), was the first to articulate the notion of contagion.

References

Lagassé P, ed. The Columbia Encyclopedia. 6th ed. New York, NY: Columbia University Press; 2000.

Wilson RF. A brief introduction to sepsis: its importance and some historical notes. Heart Lung. 1976;5:393–396.