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One of the instruments Kinyoun bought (and the only artifact remaining today) was a Zeiss microscope, the finest instrument available at that time and the product of 50 years of improvements in optics. Kinyoun’s first paper, "Observations on the Cholera Bacillus as a Means of Positive Diagnosis," indicated that the laboratory was viewed a a means to confirm clinical suspicions for ambiguous cases of cholera.