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Established Populations for the Epidemiologic Study of the Elderly (EPESE) The EPESE studies were developed to provide an epidemiologic resource for the conduct of a broad range of studies in representative samples of community-dwelling persons age 65 years and older. The three original community populations comprising the EPESE were located in East Boston, Massachusetts; Iowa and Washington Counties, Iowa; and New Haven, Connecticut. Baseline data collection began in December 1981. The Piedmont Health Survey of the Elderly (PHSE) was added as the fourth site of the EPESE project in 1985. In this site, Duke University established a baseline sample of 4,163 people 65 years of age and older, 54 percent of whom were African-American. This cohort constitutes a representative sample of the elderly in five North Carolina counties, including both urban and rural participants.