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Laporte JC, AJRCCM 2001 and Shore S. JACI 2002

- In HASM cells, IL-13, but not IL-4, attenuates Isoproterenol induced relaxation (p < 0.0001)

- IL-13 reduced Isoproterenol-induced cAMP formation

- IL-13 inhibits b-agonist driven gene expression in HASM cells through CRE dependent pathways