These figures led to development of more active R/ (see following slides). At the same time, TB clinics started making their appearance, aimed at educating the patient, preventing further spread of disease and providing support. The first TB clinic opened in Edinburgh in 1887.

In 1907, Von Pirquet described the tuberculin reaction, in 1920+ De Abreu introduced mass photography through CXR (chest X-ray) for detecting chest TB, and in 1921 BCG (Bacille Calmette Guerin) vaccination was introduced in an attempt to control the spread of the disease.