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However, peptide nucleic acid (PNA) combined with fluorescence in situ hybridization (FISH) probes have supported these daring endeavors. Many inadequate studies by PCR methodology are fragile by simple faults like very small sample sizes and not entirely trustworthy, because some of these proof-free authors are grasping at straws. Each technique may have its own little set of assumptions. Regardless, we do indeed have faith in FISH!