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This circumstance turns the procedure of validating quality of life scales into a potentially infinite process which is presented in the last line of Table 4. The essence of the process consists in a comparative study of two and more instruments on a unified sample of patients with a subsequent modification of the instruments. Such a prolonged and laborious procedure requires an even greater integration of the researchers’ efforts on the international scale. At the same time it becomes more and more obvious that such integration presupposes the development of a unified notion system that would be unambiguously interpreted and understood by all researchers.