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Traditional pharmacodynamics can be described in three ways, i.e. there are three measures that correlate with a favorable patient outome. One is the time above MIC, another is the AUC/MIC, and the third is Cmax/MIC. Each of these parameters measures the cumulative attack of susceptible bacteria. What you notice is that none restricts the time at which the concentration falls inside the selection window. Thus traditional pharmacodynamics differs conceptually from the selection window idea.