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Although the acute manifestations of influenza are usually self-limited, the cough is often severe and protracted. The disease is more severe and prolonged in older individuals. They tend to develop bacterial pneumonia, particularly in those with cardiovascular and pulmonary diseases. Primary viral pneumonia may occur but rather uncommon. Reyes syndrome is an important complication of influenza in children who are taking aspirin for fever or for other therapy. This disease involves the CNS and liver, more frequent with influenza B than influenza A.