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Many zoonotic agents infect large numbers of people, but only rarely cause clinical disease (e.g., toxoplasmosis). Other zoonotic agents almost always cause fatal disease in humans following infection (e.g., rabies). There are significant costs associated with both treating people with clinical signs and in preventing infections. The classification scheme used in this table and in the tables on slides 23, 25, and 27 was modified from Stehr-Green JK & Schantz PM, 1987, In Vet Clin NA Sm Anim Pract, 17:1-15