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In the case of Philadelphia, most of the Hispanic poulation came from Puerto Rico in the last decades and you can see that the incidence is quite similar. Life style is not so different between these two areas, so this may be one of the reasons why we do not see any differences in incidence. In the case of Hispanics in Colorado, who are mostly from Mexican origin and came to the US in the past century, the environment is quite different and that may have played a role in the differences we see in incidence. Other exlanation could be found in the concept of admixture. Chicago has received migration in the last decades from different places among them Mexico, Puerto Rico, Cuba and other areas in Latin America. That may explain the intermediate incidence in their Hispanic population.