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Journalof American Medical Association (JAMA)

Another example of clinical trial is CAST (cardiac arrhythmiasuppression trial).

This study was designed to prove if antiarrhythmic therapy is beneficialfor patients with myocardial infarction.

However, results is completely opposite. Patients with antiarrhythmictherapy
are more likely to die than those without.

If this study was not conducted, patient might be kept treated by harmfuldrug.