Department of Environmental and Occupational Health

Appointments Awards & Memberships Grants Presentations Publications Reviewing

Radosveta Koldamova - Publications

Publications

  • Koldamova RP, Lefterov IM, Staufenbiel M, et al. The LXR ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimer's disease. (2005), J.Biol.Chem., 280:4079-4088. Abstract


  • William E. Klunk, Brian J. Lopresti, Milos D. Ikonomovic, Iliya M. Lefterov, Radosveta P. Koldamova, Eric E. Abrahamson, Manik L. Debnath, Daniel P. Holt, Guo-feng Huang, Li Shao, Steven T. DeKosky, Julie C. Price and Chester A. Mathis. “Binding of the PET Tracer, Pittsburgh Compound-B (PIB), reflects the Amount of A b in Alzheimer's Disease Brain, but not in PS1/APP Mouse Brain”, ( 2005) J. Neuroscience, 25, 10598-10606


  • Koldamova RP, Staufenbiel M. and Lefterov I. Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice (2005). J.Biol.Chem., 280, 43224-43235 PMID: 16207713


  • Koldamova RP and Lefterov IM. Role of LXR and ABCA1 in the Molecular pathology of Alzheimer disease – Implications for a New Therapeutic Approach, (2007) Current Alzheimer Research, 4, 171-178. PMID: 17430243


  • Lefterov, I. Bookout, A.L. Wang, Z. Staufenbiel, M. Mangelsdorf, D. Koldamova, R. Expression profiling in APP23 mouse brain: inhibition of Aß amyloidosis and inflammation in response to LXR agonist treatment, (2007). Mol Neurodegener. 2007 Oct 22;2:20. PMID: 17953774


  • Cohen AD, Ikonomovic MD, Abrahamson EE, Paljug WR, DeKosky ST, Lefterov IM, Koldamova RP, Shao L, Debnath ML, Mason NS, Mathis CA, Klunk WE. Anti-Amyloid Effects Of Small Molecule Aβ-Binding Agents In PS1/APP Mice, (2008) Life Sciences (submitted).


  • Lefterov I., Fitz N., Staufenbiel M., Lefterov P., Koldamova R., Amyloid b oligomerization and fibrillization associated with working memory impairments in APP23/ABCA1+/- mice - implications for the role of ABCA1 in Alzheimer’s disease (2008) J. Neuroscience (submitted)


  • Cronican AA, Fitz NF, Pham T, Fogg A, Kifer B, Koldamova R, Lefterov I. Proton pump inhibitor Lansoprazole is a nuclear liver X receptor agonist. Biochem Pharmacol. 2010 Jan 7. PubMed PMID: 20060385.


  • Koldamova R, Fitz NF, Lefterov I. The role of ATP-Binding cassette transporter A1 in Alzheimer's disease and neurodegeneration. Biochem Biophys Acta. 2010 Aug;1801(8):824-30. Epub 2010 Feb 24. PubMed PMID: 20188211


  • Fitz NF, Cronican A, Pham T, Fogg A, Fauq AH, Chapman R, Lefterov I, Koldamova R. Liver X Receptor Agonist Treatment Ameliorates Amyloid Pathology and Memory Deficits Caused by High-Fat Diet in APP23 Mice. J Neurosci. 2010 May 19;30(20):6862-72. PubMed PMID: 20484628


  • Lefterov I, Fitz NF, Cronican AA, Fogg A, Lefterov P, Kodali R, Wetzel R, Koldamova R. Apolipoprotein A-I Deficiency Increases Cerebral Amyloid Angiopathy and Cognitive Deficits in APP/PS1ΔE9 mice. J Biol Chem. 2010 Nov 19;285(47):36945-57. Epub 2010 Aug 25. PMID: 20739292

Non-Print Media

  1. Koldamova R and Lefterov I. Comment on paper by Lee JH. et al., 2009, Alzheimer Research Forum, 30 Sep 2009; http://www.alzforum.org/pap/annotation.asp?powID=94582#{03789BCC-B657-4EEB-B8DD-4C42F67BA874}

  2. Koldamova R. Comment on paper by Jiang et al., (2008). Alzheimer Research Forum. 17 June, 2008; http://www.alzforum.org/new/detail.asp?id=1849#{E464D97D-9668-4277-BE89-6ADABD3C389A}

  3. Koldamova R. Comment on paper by Kim et al., (2008). Alzheimer Research Forum, 5 Feb 2008; http://www.alzforum.org/pap/annotation.asp?powID=74035#{BE8C42ED-A347-4F5D-A29C-5ECB8629E371}