Research into the causes of Schizophrenia, Bipolar Disorder, and Related Illnesses

Neurobehavioral Family Study

Funding for this work provided by the NIMH
ref. #R01 MH63480

Purpose:

This project proposes a new strategy for the study of brain and behavior by examining genetic influences on cognitive abilities among persons affected by schizophrenia and related conditions and their extended family members.

These measures are an extension of our general purpose of investigating liability genes and risk factors for schizophrenia and schizoaffective disorder.

This project is intended to give greater insight into the inheritance of various cognitive features of the schizophrenia phenotype, ultimately leading to better diagnosis, treatment, and preventative measures.

Eligibility:

Caucasian families with two or more first-degree relatives affected with schizophrenia or schizoaffective disorder. (Siblings and parent-child relationships qualify as first-degree relatives.)
10-20+ additional extended family members (e.g., aunts/uncles, grandparents, cousins) are also needed to participate.
All participants diagnosed with schizophrenia or schizoaffective disorder must be 14 years or older. Unaffected relatives must be 18 years or older.

Procedures:

All participants will be asked to undergo the following procedures:

Blood Draw
Diagnostic Interview
Family Interview
Computerized Cognitive tests

All procedures will be carried out by a qualified and experienced clinical interviewer. All procedures can be done in the participant’s home or other convenient location. In most cases, all procedures can be completed in one visit.

Payments:

All participants will be paid $100 upon completion of the study in appreciation for their time and contribution.

This is not a treatment study. Thus, there will be no changes in treatment requested to participate in this study. All information will be kept strictly confidential.

For more information, please call 1-877-363-5895.