Search Pubmed for publications from the Trakselis Laboratory

23) Mohan, S., Rizaldy, R., Das D., Bauer R.J., Heroux A., Trakselis, M.A., Hildebrand J.D., Vandemark, A.P. (2012) Structure of the shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, rock binding, and apical constriction, Mol Biol Cell, in press.

22) Bauer, R.J., Begley M.T., and Trakselis, M.A. (2012) Kinetics and fidelity of polymerization by DNA polymerase III from Sulfolobus solfataricus, Biochemistry, 51, 1996-2007.

21) Zuo, Z., Lin, H-K, and Trakselis, M.A. (2011) Strand annealing and terminal transferase activities of a B-family DNA Polymerase, Biochemistry, 50, 5379-5370.

20) Graham, B.W., Schauer, G.D., Leuba, S.H. and Trakselis, M.A. (2011) Steric Exclusion and Wrapping of the Excluded DNA Strand Occurs Along Discrete External Binding Paths During MCM Helicase Unwinding, NAR, 39, 6585.

19) Zuo, Z., Rodgers, C., Mikheikin, A.L., and Trakselis, M.A. (2010) Characterization of a functional DnaG-type primase in Archaea: Implications for a dual primase system, J. Mol. Biol, 397, 664-676 .

18) Mikheikin A.L., Lin, H-K, Mehta, P., Jen-Jacobson, L., and Trakselis, M.A. (2009) The DNA replication polymerase from Sulfolobus solfataricus forms a multimer when bound to DNA, NAR, 37, 7194-205 .

17) Rothenberg, E., Trakselis, M.A., Bell, S.D., and Ha, T. (2007) MCM Forked substrate specificity involves dynamic interaction with the 5'-tail. JBC, 282, 34229-34.

16) McGeoch, A.T., Trakselis, M.A., Laskey, R.A., and Bell, S.D. (2005) Organization of the Archaeal MCM Complex on DNA and Implications for a Helicase Mechanism. Nat Struc. Mol. Biol., 12, 756-762.

15) Trakselis, M.A., Alley, S.C., and Ishmael, F.T. (2005) Identification of Protein-Protein Interactions Using Novel Crosslinking Reagents. Bioconjugate Techniques, 16, 741-750. (Cover)

14) Norcum, M.T., Warrington, A., Spiering, M.M., Ishmael, F.T., Trakselis, M.A., and Benkovic, S.J. (2005) Architecture of the Bacteriophage T4 Primosome: Electron Microscopy Studies of gp41 and gp61. PNAS, 102, 3623-3626.

13) Zhang, Z, Spiering, M.M., Trakselis, M.A., Ishmael, F.T., Xi, J., Benkovic, S.J., and Hammes, G.G. (2005) Assembly of the Bacteriophage T4 Primosome: Single Molecule and Ensemble Studies. PNAS, 102, 3254-3259.

12) Millar, D., Trakselis, M.A., and Benkovic, S.J. (2004) The Trimeric Bacteriophage T4 Clamp is Open at One Interface in Solution. Biochemistry, 43, 12723-7.

11) Zhang, Z., Spiering, M.M., Berdis, A.J., Trakselis, M.A., and Benkovic, S.J. (2004) 'Screw-cap' Clamp Loader Proteins that Thread. Nat. Struc. Biol. 11, 580-581.

10) Trakselis, M.A. and Bell, S.D. (2004) Loader of the Rings. Nature, 249, 798-799.

9) Yang, J., Zhuang, Z., Roccasecca, R., Trakselis, M.A., and Benkovic, S.J. (2004) The Dynamic Processivity of the T4 Polymerase during Replication. PNAS, 101, 8289-8294.

8) Trakselis, M.A., Roccasecca, R., Yang, J., Valentine, A., and Benkovic, S.J. (2003) Dissociative Properties of the Proteins within the Bacteriophage T4 Replisome. JBC, 278, 49839-49849.

7) Yang, J., Trakselis, M.A., Roccasecca, R., and Benkovic, S.J. (2003) The Application of a Minicircle Substrate in the Study of the Coordinated T4 DNA Replication. JBC, 278, 49828-49838.

6) Ishmael, F.T. Trakselis, M.A., and Benkovic, S.J. (2003) Protein-Protein Interactions in the Bacteriophage T4 Replisome: The Leading Strand Holoenzyme is Physically Linked to the Lagging Strand Holoenzyme and Primosome. JBC, 278, 3145-3152.

5) Trakselis, M.A., Berdis, A.J., Benkovic, S.J. (2003) Examination of the Role of the Clamp-Loader and ATP Hydrolysis in the Formation of the Bacteriophage T4 Polymerase Holoenzyme. J. Mol. Biol., 326, 435-451.

4) Trakselis, M.A. and Benkovic, S.J. (2001) Intricacies in ATP Dependent Clamp Loading:  Variations Across Replication Systems. Structure, 9, 999-1004.

3) Alley, S.C., Trakselis, M.A., Mayer, M.U., Ishmael, F.T., Jones, A.D., Benkovic, S.J. (2001) Building a Replisome Solution Structure by Elucidation of Protein-Protein Interactions in the Bacteriophage T4 DNA Polymerase Holoenzyme. J. Biol. Chem., 276, 39340-39349.

2) Trakselis, M.A., Mayer, M.U., Ishmael, F.T., Roccasecca R., and Benkovic, S.J. (2001) Use of Small Molecules to Determine Dynamic Protein-Protein Interactions in the Multi-Protein Bacteriophage T4 Replication Complex. TIBS, 26, 566-572.

1) Trakselis, M.A., Alley, S.C., Abel-Santos, E., Benkovic, S.J. (2001) Creating a Dynamic Picture of the Sliding Clamp During T4 DNA Polymerase Holoenzyme Assembly Using Fluorescence Resonance Energy Transfer. PNAS, 98, 8368-8375.

 

   
 
© 2008 Michael A. Trakselis, Dept. of Chemistry, University of Pittsburgh
 
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