Message from the Director

The Musculoskeletal Research Center (MSRC) was established in 1990 for the purpose of orthopaedic education and research. Since then, the MSRC has been a flourishing enterprise where engineers, biologists, physicians and surgeons work together to teach and mentor highly qualified students, research fellows, and residents. Our multidisciplinary integrative research programs expose all to state-of-the-art translational research in orthopaedic medicine. Our laboratories are designed to allow researchers to collaborate seamlessly and perform research projects at the molecular, cellular, tissue, and joint levels.

Our current research is focused in two areas: 1) measurement of the properties of ligaments and tendons and joint mechanics and 2) functional tissue engineering (FTE) and regeneration of ligaments and tendons. Our Mechanobiology, Tissue Mechanics, and Knee Kinematics and Joint Robotics Laboratories are organized to investigate the cellular and molecular responses to mechanical stimuli to improve the outcome of ligament and tendon healing. With the innovative use of robotic technology (developed in our research center for over two decades) in combination with numerical methods for modeling, we examine the contribution of individual ligaments and tendons to joint function. Currently, we are also exploring the use of biodegradable magnesium (Mg) and Mg alloys for ligament regeneration.

The MSRC offers a wide variety of opportunities for motivated undergraduate and graduate students to learn and conduct orthopaedic research. Each year, we offer the Summer Undergraduate Research Program, which serves to expose students to sound scientific research. We also welcome international research fellows from diverse backgrounds to study with us.

The MSRC also strives to serve the scientific community, particularly the fields of orthopaedic sports medicine and biomechanics, such as the WACBE, ORS, BMES, American Society of Mechanical Engineers (ASME), and so on. Our center has also hosted members of the general public ranging from aspiring middle school students (and their parents), medical and graduate students, visitors from other academic institutions and industry for tours and outreach programs.

Together, the MSRC has earned a national and international reputation of excellence in basic and translational research.

Sincerely yours,

Savio L-Y. Woo, Ph.D., D.Sc., D.Eng. Director

Musculoskeletal Research Center 2013