Publications
Recent Refereed Publications (2004-2014) | Refereed Publications Full List | Reviews

Recent Refereed Publications (2004-2014)
(Click here for a full list of publications)

  • Zhang, J.; Wang, JH-C. PRP treatment effects on degenerative tendinopathy - an in vitro model study. MLTJ, 2014. 9(2): p. e87706.[pubmed]

  • Wang, JH-C. Can PRP effectively treat injured tendons (Commentary) MLTJ, 2014. 4(1): p. 10-7.[MLTJ]

  • Zhang, J.; Jiang, D.; Wang, JH-C. Prostaglandin E2 (PGE2) exerts biphasic effects on human tendon stem cells. PLoS ONE,9(2): p. e87706.[pubmed]

  • Zhang, J.; Pan, T.; Wang, JH-C. Cryotherapy suppresses tendon inflammation in an animal model. Journal of Orthopaedic Translation, 2014. 2(2): p. 75-81. [ScienceDirect]

  • Jamison, J.; Lauffenburger, D.; Wang, JH-C.; Wells, A. PKC-delta localization at the membrane increases matrix traction force dependent on PLC-gamma-1/EGFR signaling. PLoS ONE 8(10):e77434, 2013. [pubmed]

  • Yuan,T.;Zhang C.Q.; Wang, JH-C. Augmenting Tendon and Ligament Repair with Platelet-Rich Plasma (PRP). MLTJ, 2013;3(3):139-149 [MTLJ]

  • Zhang, J., et al., HGF mediates the anti-inflammatory effects of PRP on injured tendons. PloS One, 2013. 8(6): p. e67303.[PubMed]

  • Zhang, J.; Wang, JH-C. The effects of mechanical loading on tendons - an in vivo and in vitro model study, PloS One, 2013. 8(8): p. e71740.[PubMed]

  • Maeda, E.; Hagiwara, Y.; Wang, JH-C.; Ohashi, T. A new experimental system for simultaneous application of cyclic tensile strain and fluid shear stress to tenocytes in vitro.Biomedical Microdevices,2013. 15(6): p. 1067-75.[PubMed]

  • Satish, L.; Johnson, S.; Raykha, C.; O'Gorman, D.B.; Gan, B.S.; Wang, JH-C.; Kathju, S. Increased CCT-eta expression is a marker of latent and active disease and a modulator of fibroblast contractility in Dupuytren's contracture. Cell Stress Chaperones, 18(4): 397-404,2013. [PubMed]

  • Zhang, J.; Wang, JH-C. Human tendon stem cells better maintain their stemness in hypoxic culture conditions. PloS One,8(4): e61424.2013. [PubMed]

  • Yang, Y.; Zhang, J.; Qian, Y.; Dong, S.; Huang, H.; Boada, F.E.; Fu, F.; Wang, JH-C. Superparamagnetic iron oxide is suitable to label tendon stem cells and track them in vivo with MR imaging, Annals of Biomedical Eng, in press. [PubMed]

  • Ellman, M.B.; Kim, J.; An, H.S.; Chen, D.; Kc, R.; Li, X.; Xiao, G.Z.; Yan, D.; Suh, J.; van Wijnen, A.J.; Wang, JH-C.; Kim, S.G.; Im, H.J. Lactoferricin enhances BMP7-stimulated anabolic pathways in intervertebral disc cells. Gene, 524(2): 282-291.2013. [PubMed]

  • Zhang, J.; Keenan, C. Wang, JH-C. The effects of dexamethasone on human patellar tendon stem cells: implications for dexamethasone treatment of tendon injury, J Orthop Res,31(1): 105-110,2013. [PubMed]

  • Zhang, J.; Wang, JH-C. BMP-2 mediates PGE2-induced reduction of proliferation and osteogenic differentiation of human tendon stem cells. J Orthop Res, 30(1):47-52, 2012. [PubMed]

  • Zhang J, Pan T, Im H-J, Fu F, Wang JH-C. Differential properties of human ACL and MCL stem cells may be responsible for their differential healing capacity. BMC Medicine, 9:68, 2011. [PubMed]

  • Zhang J, Wang JH-C. BMP-2 mediates PGE2-induced reduction of proliferation and osteogenic differentiation of human tendon stem cells. J Orthop Res, 2011. [PubMed]

  • Liu ZM, Blattner SM, Tu Y, Tisherman R, Wang JH-C, Kretzler M, Wu C. {alpha}-actinin-4 and CLP36 deficiencies contribute to podocyte defects in multiple human glomerulopathies. J Biol Chem, 286:30795-30805, 2011. [PubMed]

  • Zhang J, Li B, Wang JH-C. The role of engineered tendon matrix in the stemness of tendon stem cells in vitro and the promotion of tendon-like tissue formation in vivo. Biomaterials, 32:6972-6981, 2011. [PubMed]

  • Shao, H.; Wang, JH-C.; Pollak, M.R.; Well, A. a-Actinin-4 is essential for maintaining the spreading, motility and contractility of fibroblasts. PLoS ONE 5(11):e13921, 2010.

  • Zhou J, Kim HY, Wang JH-C, Davidson LA. Macroscopic stiffening of embryonic tissues via microtubules, Rho-GEF, and assembly of contractile bundles of actyomyosin. Development, 137:2785-2794, 2010. [PubMed]

  • Zhang J, Wang JH-C. Platelet-rich plasma releasate promotes differentiation of tendon stem cells into active tenocytes. American Journal of Sports Medicine, 38:2477-2486, 2010. [PubMed]

  • Zhang J, Pan T, Liu Y, Wang JH-C. Mouse treadmill running enhances tendons by expanding the pool of tendon stem cells (TSCs) and TSC-related cellular production of collagen. J Orthop Res, 2010. [PubMed]

  • Satish L, Johnson S, Wang JH-C, Post JC, Ehrlich GD, Kathju S. Chaperonin containing T-complex polypeptide subunit eta (CCT-eta) is a specific regulator of fibroblast motility and contractility. PLoS One, 2010. [PubMed]

  • Zhang J, Wang JH-C. Characterization of differential properties of rabbit tendon stem cells and tenocytes. BMC Musculoskeletal Disorders, 11:10, 2010. [PubMed]

  • Li, X.; Ellman, M.; Muddasani, P.; Wang, JH-C.; Cs-Szabo1, G.; van Wijnen, A.J.; and Im, H.J. PGE2 and its cognate EP receptors control human adult articular cartilage homeostasis and are linked to the pathophysiology of osteoarthritis. Arthritis & Rheumatism, 60 (2)513-523, 2009.

  • Zhang J, Wang JH-C. Mechanobiological response of tendon stem cells: implications of tendon homeostasis and pathogenesis of tendinopathy. J Orthop Res, 2009. [PubMed]

  • Zhang J, Wang JH-C. High levels of PGE2 are produced in tendons subjected to repetitive mechanical loading and induce differentiation of tendon stem cells into non-tenocytes. J Orthop Res, 2009. [PubMed]

  • Szczodry M, Zhang J, Lim CT, Davitt HL, Yeager T, Fu F, Wang JH-C. Treadmill running exercise results in the presence of numerous myofibroblasts in mouse patellar tendons. J Orthop Res, 2009. [PubMed]

  • Li B, Li F, Puskar KM, Wang JH-C. Spatial patterning of cell proliferation and differentiation depends on mechanical stress magnitude. J Biomech, 42:1622-627, 2009.[PubMed].

  • Ekdahl M, Wang JH-C, Ronga M, Fu FH. Graft healing in anterior cruciate ligament reconstruction. Knee Surgery, Sports Traumatology, Arthroscopy, 16:935-4, 2008.[PubMed].

  • Li B, Lin M, Tang Y, Wang B, Wang JH-C. A novel functional assessment of the differentiation of micropatterned muscle cells. Journal of Biomechanics, 41:3349-3353, 2008. [PubMed]

  • Wang JH-C, Thampatty, BP. Mechanobiology of adult and stem cells. The International Review of Cell and Molecular Biology, 271:301-346, 2008. [PubMed].

  • Li F, Li B, Wang QM, Wang JH-C. Cell shape regulates collagen type I expression in human tendon fibroblasts. Cell Motil Cytoskel, 65:332-341, 2008. [PubMed].

  • Li, F.; Wang, JH-C.; Wang, Q.M. Thickness shear mode acoustic wave sensors for characterizing the viscoelastic properties of cell monolayer. Sensors and Actuators B: Chemical 128: 399-406, 2008.

  • Li B, Xie L, Starr ZC, Yang ZC, Lin J-S, Wang JH-C. Development of Micropost Force Sensor Array with Culture Experiments for Determination of Cell Traction Forces. Cell Motility & Cytoskeleton, 64:509-18, 2007. [PubMed].

  • Chen JX, Li HX, SundarRaj N, Wang JH-C. Alpha-smooth muscle actin expression enhances cell traction force. Cell Motility & Cytoskeleton, 64:248-57, 2007.[PubMed].

  • Thampatty BP, Li HX, Im HJ, Wang JH-C. EP4 receptor regulates collagen type-I, MMP-1, and MMP-3 gene expression in human tendon fibroblasts in response to IL-1beta treatment, Gene, 386:154-161, 2007. [PubMed].

  • Li, F.; Wang, JH-C.; Wang, Q.M. Monitoring cell adhesion by using thickness shear mode acoustic wave sensors. Biosensors and Bioelectronics 23(1): 42-50, 2007.

  • Li B, Chen JX, Wang JH-C. RGD peptide-conjugated poly(dimethylsiloxane) promotes adhesion, proliferation, and collagen secretion of human fibroblasts. J Biomed Mater Res, 2006. [PubMed].

  • Thampatty BP, Wang JH-C. A new approach to study fibroblast migration. Cell Motility & Cytoskeleton, 64:1, 2007. [PubMed].

  • Yang ZC, Chen JX, Lin J-S, Wang JH-C. Determining substrate displacement and cell traction fields - a new approach, J Theoretical Biology,242:607-616, 2006.[PubMed].

  • Chen J, Iosifidis M, Zhu J, Tatarintsev I, Wang JH-C. Vanadate ingestion enhances the organization and collagen fibril diameters of rat healing MCLs. Knee Surg Sports Traumatol Arthrosc, 14:750-755, 2006. [PubMed].

  • Thampatty BP, Im HJ, Wang JH-C. Leukotriene B4 at low dosage negates the catabolic effect of prostaglandin E2 in human patellar tendon fibroblasts. Gene, 372:103-109, 2006. [PubMed].

  • Agarwal C, Britton ZT, Alaseirlis DA, Li Y, Wang JH-C. Healing and normal fibroblasts exhibit differential proliferation, collagen production, alpha-SMA expression, and contraction. Ann Biomed Eng, 34:653-659, 2006. [PubMed].

  • Yang GG, Im HJ, Wang JH-C. Repetitive mechanical stretching modulates IL-1beta induced COX-2, MMP-1 expression, and PGE(2) production in human patellar tendon fibroblasts. Gene, 363:166-172, 2005. [PubMed].

  • Alaseirlis, D.A., Li, Y., Cilli, F., Fu, F.H., Wang, JH-C. Decreasing inflammatory response of injured patellar tendons results in increased collagen fibril diameters. Connect Tissue Res, 46:3, 2005. [PubMed].

  • Wang JH-C, Yang G, Li Z. Controlling cell responses to cyclic mechanical stretching. Ann Biomed Eng, 33:337-342, 2005. [PubMed].

  • Khan MH, Li Z, Wang JH-C. Repeated exposure of tendon to prostaglandin-E2 leads to localized tendon degeneration. Clin J Sport Med, 15:27-3, 2005. [PubMed].

  • Yang G, Crawford RC, Wang JH-C. Proliferation and collagen production of human patellar tendon fibroblasts in response to cyclic uniaxial stretching in serum-free conditions. J Biomech, 37:1543-1550, 2004. [PubMed].

  • Cilli F, Khan M, Fu F, Wang JH-C. Prostaglandin E2 affects proliferation and collagen synthesis by human patellar tendon fibroblasts. Clin J Sport Med, 14:232-36, 2004. [PubMed].

  • Wang JH-C, Li Z, Yang G, Khan M. Repetitively stretched tendon fibroblasts produce inflammatory mediators. Clin Orthop Relat Res, 422:243-50, 2004. [PubMed].

  • Campbell BH, Agarwal C, Wang JH-C. TGF-beta1, TGF-beta3, and PGE(2) regulate contraction of human patellar tendon fibroblasts. Biomech Model Mechanobiol, 2:239-245, 2004. [PubMed].

  • Cetin S, Ford HR, Sysko LR, Agarwal C, Wang JH-C, Neal MD, Baty C, Apodaca G, Hackam DJ. Endotoxin inhibits intestinal epithelial restitution through activation of Rho-GTPase and increased focal adhesions. J Biol Chem, 279:24592-4600, 2004. [PubMed].

  • Musahl V, Abramowitch S, Gilbert TW, Tsuda E, Wang JH-C , Woo SL-Y. The use of porcine small intestinal submucosa to enhance the healing of the medial collateral ligament :a functional tissue engineering study in rabbits. J Orthop Res, 22:214 -220, 2004. [PubMed].

  • Wang JH-C, Yang G, Li Z, Shen W. Fibroblast responses to cyclic mechanical stretching depend on cell orientation to the stretching direction. J Biomech, 37:573-76, 2004. [PubMed].

  • Peperzak KA, Gilbert TW, Wang JH-C. A multi-station dynamic-culture force monitor system to study cell mechanobiology. Med Eng Phys, 26:355-58, 2004. [PubMed].

  • Li Z, Yang G, Khan M, Stone D, Woo SL, Wang JH-C. Inflammatory response of human tendon fibroblasts to cyclic mechanical stretching. Am J Sports Med, 32:435-440, 2004. [PubMed].