Publications
Full List Refereed Publications | Recent Refereed Publications (2013-2023) | Book Chapters

Refereed Publications (Full List)
(Click here for list of Recent Refereed Publications )

  1. Zhang, J.; Brown, R.; Hogan, M.V.; Wang, JH-C. Mitigating scar tissue formation in tendon injuies: Targeting HMGB1, AMPK activation, and myofibroblast migration all at once. Pharmaceuticals, 16(12): 1739, 2023.

  2. Zhang, J.; Brown, R.; Hogan, M.V.; Onishi, K. Wang, JH-C. Metformin improves tendon degeneration by blocking translocation of HMGB1 and suppressing tendon inflammation and senescence in aging mice. J Orthop Res, 41(6):1162-1176, 2023.

  3. Zhang, J.; Li, F.; Augi, T.; Williamson, K.M.; Onishi, K.; Hogan, M.V.; Neal, M.D. Wang, JH-C. Platelet HMGB1 in platelet-rich plasma (PRP) prmotes tendon wound healing. PLoS ONE, 16(9), 2021, https://doi.org/10.1371/journal.pone.0251166.

  4. Nie, D.; Zhou, Y.; Wang, W.; Zhang, J.; Wang, JH-C. Mechanical overloading-induced activation of mTOR signaling in tendon stem/progenitor cells contributes to tendinopathy development. Front. Cell Develop. Biol., 2021, https://doi.org/10.3389/fcell.2021.687856.

  5. Nie, D.; Zhang, J.; Zhou, Y.; Sun, J.; Wang, W.; Wang, JH-C. Rapamycin Treatment of Tendon Stem/Progenitor Cells Reduces Cellular Senescence by Upregulating Autophagy. Stem Cell Intl, 2021, Article ID 6638249, https://doi.org/10.1155/2021/6638249.

  6. Zhang, J.; Li, F.; Williamson, K.M.; Tan, S.; Scott, D.; Onishi, K.; Hogan, M.V.; Wang, JH-C. Characterization of the structure, vascularity, and stem/progenitor cell populations in porcine Achilles tendon. Cell and Tissue Res, 2021 Jan 26.doi: 10.1007/s00441-020-03379-3.

  7. Zhang, J.; Nie, D.; Williamson, K.; McDowell, A.; Hogan, M.V.; Wang, JH-C. Moderate and intensive mechanical loading differentially modulate the phenotype of tendon stem/progenitor cells in vivo. PLoS ONE, Dec 29;15(12):e0242640. doi: 10.1371/journal.pone.0242640. eCollection 2020.

  8. Zhang, J.; Li, F.; Nie, D; Onishi, K.; Hogan, M.V.; Wang, JH-C. Effect of metformin on development of tendinopathy due to mechanical overloading in an animal model. Foot and Ankle Int, 41(12) 1455-1465, 2020. (2020 J. Leonard Goldner Award Winner).

  9. Hogan, M.V.; Scott, D.M.; Canton, S.P.; LaBaze, D.; Yan, A.Y.; Wang, JH-C. Biologic therapies for foot and ankle injuries. Expert Opin Biol Therap, 2020 Dec 31;1-14. doi: 10.1080/14712598.2021.1866534.

  10. Neph, A.; Schroeder, A.; Enseki, K.R.; Everts, P.A.; Wang, JH-C.; Onishi, K. Role of Mechanical Loading for Platelet-Rich Plasma Treated Tendinopathy. Current Sports Med Rep. 2020 Jun;19(6):209-216. doi: 10.1249/JSR.0000000000000719.

  11. Yazdani, H.O.; Kaltenmeier, C.; Morder, K.; Moon, J.; Traczek, M.; Loughran, P.; Zamora, R.; Vodovotz, Y.; Li, F.; Wang, JH-C.; Geller, D.A.; Simmons, R.L.; Tohme, S. Exercise training decreases hepatic injury via changes in immune response to liver ischemia/reperfusion in mice. Hepatology, Sep 14.doi: 10.1002/hep.31552, 2020.

  12. Ferrer, GA.; Miller, RM.; Yoshida, M.; Wang, JH-C.; Musahl,V.; Debski, R. Correlation of quantitative ultrasound measures and supraspinatus tendon quality: a pilot study. J Med Ultrasound, 28 (3): 162-168, 2020.

  13. Ferrer, GA.; Miller, RM.; Yoshida, M.; Wang, JH-C.; Musahl, V.; Debski,R. Localized rotator cuff degeneration for cadaveric shoulders with and without tears isolated to the supraspinatus tendon.Clin Anat, 2019, https://doi.org/10.1002/ca.23526.

  14. Zhao, G.; Zhang, J.; Nie, D.; Zhou, Y.; Li, F.; Onishi, K.; Billiar,T.; Wang, JH-C. HMGB1 mediates the development of tendinopathy due to mechanical overloading. PLoS ONE 14(9):e2222369, 2019.

  15. Wu, H.; Wang, JH-C.; Wang, QM.; Wang, JH-C. A study of Love wave acoustic biosensors monitoring the adhesion process of tendon stem cells (TSCs). Eur Biophys J, https://doi.org/10.1007/s00249-019-01349-4, 2019.

  16. Zhang, ZX.; Zhu, J.; Zhou, Y.; Thampatty, BP.; Wang, JH-C. Tendon stem/progenitor cells and their interactions with extracellular matrix and mechanical loading. Stem cell International, Oct 13, eCollection https://doi.org/10.1155/2019/3674647, 2019.

  17. Milano, G.; Sánchez, M.; Jo, CH.; Saccomanno, MF., Thampatty, BP.; Wang, JH-C. Platelet-rich plasma in orthopaedic sports medicine: state of the art. JISAKOS, 4(4):1–8, 2019.

  18. Neph, A.; Onishi, K.; Rocha, JL.; Wang, JH-C. Myths and facts of in-office regenerative procedures for tendinopathy: literature review. American Journal of Physical Medicine and Rehabilitation, Jun;98(6):500-511, 2019.

  19. Zhang, J.; Nie, D.; Rocha, JL.; Hogan, MV.; Wang, JH-C. Selectively activated PRP exerts differential effects on tendon stem/progenitor cells and tendon healing. Journal of Tissue Engineering, Jan-Dec; 10: 2041731418820034, 2019.

  20. Chen, B.; Zhang, J.; Nie, D.; Zhao, G.; Fu, F.; Wang, JH-C. Characterization of the structure of rabbit ACL and its stem/progenitor cells. Journal of Cellular Biochemistry, In Press (10/15/18).

  21. Zhang, J.; Nie, D.; Rocha, JL; Hogan, MV; Wang, JH-C. Characterization of the structure, cells, and cellular mechanobiological response of human plantar fascia. Journal of Tissue Engineering, 9:1-16, 2018.

  22. Washburn, N.; Onishi, K.; and Wang, JH-C.. "Ultrasound elastography and ultrasound tissue characterization for tendon evaluation." Journal of Orthopaedic Translation, 15:1-12,2018.

  23. Zhang, J., Wang, JH-C. "Maintenance of tendon stem/progenitor cells in culture." Methods in Molecular Biology, Vol 1842, Eds. Shree Ram Singh and Pranela Rameshwar, 2018.

  24. Wang, JH-C.; Thampatty, B.P. : "Advances in tendon mechanobiology." Mechanobiology in Health and Disease (1st edition), ed. Stefaan Verbruggen, Academic Press, 2018.

  25. Zhou, Y.; Zhang, Y.; Yang, J.; Narava, M.; Zhao, G.; Yuan, T.; Wu, H.; Zheng, N.; Hogan, M.V.; Wang, JH-C. "Kartogenin with PRP promotes the formation of fibrocartilage zone in the tendon-bone interface." Journal of Tissue Eng and Regenerative Medicine, 2017. doi: 10.1002/term.2258.

  26. Bhavani, P.T.; Wang, JH-C. "Mechanobiology of Young and Aging Tendons: In Vivo Studies with Treadmill Running." Journal of Orthopaedic Research 2017, doi: 10.1002/jor.23761.

  27. Jia, H.; Ma, X.; Wei, Y.; Tong, W.; Tower, R. ; Chandra, A.; Wang, L.; Sun, Z.; Yang, Z.; Badar, F.; Zhang, K.; Tseng, W.; Kramer, I.; Kneissel, M.; Xia, Y.; Liu, X.; Wang, JH-C.; Han, L.; Enomoto-Iwamoto1, M.; Qin, L. "Subchondral bone plate sclerosis during late osteoarthritis is caused by loading-induced reduction in Sclerostin." Arthritis & Rheumatology. doi: 10.1002/art.40351

  28. Zhang, J.; Yuan, T.; Zheng, N.; Zhou, Y.; Hogan, M.V.; Wang, JH-C. "The combined use of Kartogenin (KGN) and PRP promotes fibrocartilage formation in Wounded Rat Achilles Tendon Entheses." Bone Joint Res. 6(4):231-244, 2017.

  29. Wu, H.; Xiong, X.; Zu, H.; Wang, JH-C.; Wang, Q.-M. "Theoretical analysis of Love wave biosensors in liquid with a viscoelastic wave guiding layer" Journal of Applied Physics, 121: 054501, 2017.

  30. Yiqin Zhou; Jianying Zhang; Jinsong Yang; Manoj Narava; Guangyi Zhao; Ting Yuan; Haishan Wu; Nigel Zheng; MaCalus V. Hogan and Wang, JH-C. "Kartogenin with PRP promotes the formation of fibrocartilage zone in the tendon-bone interface" J Tissue Eng Regen Med 2017. DOI: 10.1002/term.2258. Epub 2017 Jan 27

  31. Zhou, Y.; *Wang, JH-C. PRP treatment efficacy for tendinopathy: a review of basic science studies. BioMed Res Int, 2016:9103792. doi: 10.1115/2016/9103792.

  32. Li, Z-M.; *Wang, JH-C.; Woo, SL-Y. Biomechanics and Mechanobiology of Ligaments and Tendons, Journal of Medical Biomechanics, 31: 301-307, 2016.

  33. *Wang, JH-C.; Nirmala, X. Perspectives on Improving the Efficacy of PRP Treatment for Tendinopathy, Journal of Musculoskeletal Disorders and Treatment, 2:015, 2016.

  34. Wang, JH-C.; Nirmala, X. Application of TSCs and PRP to treat tendon injuries. Oper Tech Orthop, 26 (2): 68-72, 2016.

  35. Wang, JH-C.; Komatsu, I. "Tendon Stem Cells: Mechanobiology and Development of Tendinopathy." Cytoskeleton Adv Exp Med Biol, Vol. 920, Paul Ackermann and David A. Hart (Eds): Metabolic Influences on Risk for Tendon Disorders, 2016.

  36. Hossain, M; Zhao, G; Woo, M; Wang; Wang, JH-C. ; Jian-Ping. "Deletion of calponin 2 in mouse fibroblasts increases myosin II-dependent cell traction force." Biochemistry 2016. 2016 Nov 1;55(43):6046-6055

  37. Wu, H.; Zhao, G.; Zu, H.; Wang, JH-C.; Wang, Q.M. Real-time monitoring of platelet activation using quartz thickness shear mode (TSM) resonator sensors. Biophysical J., 110: 669-679, 2016. [Pubmed]

  38. Yuan, T.; Zhang, J.; Zhao, G.; Zhou, Y.; Zhang, C.Q.; Wang, JH-C. Creating an animal model of tendinopathy by inducing chondrogenic differentiation with kartogenin. PloS ONE, 11(2):e0148557, 2016. [Pubmed]

  39. Zhang, J.; Yuan, T.; Wang, JH-C. Moderate treadmill running exercise prior to tendon injury enhances wound healing aging rats. Ontotarget, 2016 Feb 23;7(8):8498-512 [Pubmed]

  40. Zhang, J.; Wang, JH-C.. Aging and exercise mitigates the detrimental effects on tendon stem cells. PloS ONE, 10(6):e0130454, 2015. [PLOS]

  41. Kim, J-S.; Ali, M.H.; Wydra, F.; Li, X; Hamilton, J.; An, H.S.; Cs-Szabo, G.; Andrews, S.; Moric, M.; Xiao, G.; Wang, JH-C.; Chen, D.; Cavanaugh, J.M; Im, Hee-Jeong. Characterization of degenerative human facet joints and facet joint capsular tissues, Osteoarthritis and Cartilage,23(12): 2242-2251. [ScienceDirect]

  42. Wang, JH-C.; Zhou, Y,Q. New advancements on tendon stem cells. International Journal of Orthopaedics, 36 (3): 163-167, 2015.

  43. Wu, H.; Zhao, G.; Zu, H.; Wang, JH-C.; Wang, Q. M. Aging-related Viscoelasticity Variation of Tendon Stem Cells (TSC) Characterized by Quartz Thickness Shear Mode (TSM) Resonators. Sensors & Actuators: B. 210: 369-380, 2015. (*corresponding author) [PMC]

  44. Sun, H.B.; Schaniel, C.; Leong, D.J.; Lemischka, I.; and Wang, JH-C. Biology and mechano-response of tendon cells: progress overview and perspective. J Orthop Res 33(6): 785-792, 2015. [PubMed]

  45. Wang, JH-C.; Zhang, J.; Nirmala, X. Advancements in the treatment and repair of tendon injuries. Current Tissue Engineering 3(2) 71-81, 2014. [Iink]

  46. Wu, H.; Zhao, G.; Zu, H.; Wang, JH-C..; Wang, Q. M. Label-free Detection of Protein Released during Platelet Activation by CNT-Enhanced Love Mode SAW Sensors. 2014 IEEE International Ultrasonics Symposium Proceedings: 1528-1531, 2014.[IEEE]

  47. Zhang, J.; Wang, JH-C. Kartogenin (KGN) induces cartilage-like tissue formation in tendon-bone junction. Bone Research 2: 14008, 2014.[PubMed]

  48. Zhang, J.; Wang, JH-C. PRP treatment effects on degenerative tendinopathy - an in vitro model study. MLTJ 4 (1): 10-17, 2014.[PubMed]

  49. Wang, JH-C.. Can PRP effectively treat injured tendons (Commentary)? MLTJ 4 (1): 35-37, 2014[MLTJ]

  50. Zhang, J.; Jiang, D.; Wang, JH-C. Prostaglandin E2 (PGE2) exerts biphasic effects on human tendon stem cells. PLoS ONE,9(2): p. e87706.[PubMed]

  51. Zhang, J.; Pan, T.; Wang, JH-C. Cryotherapy suppresses tendon inflammation in an animal model. Journal of Orthopaedic Translation, 2(2): p. 75-81, 2014 [ScienceDirect]

  52. Jamison, J.; Lauffenburger, D.; Wang, JH-C.; Wells, A. PKC-delta localization at the membrane increases matrix traction force dependent on PLC-gamma-1/EGFR signaling. PLoS ONE 8(10):e77434, 2013. [PubMed]

  53. Yuan,T.;Zhang C.Q.; Wang, JH-C. Augmenting Tendon and Ligament Repair with Platelet-Rich Plasma (PRP). MLTJ, 2013;3(3):139-149 [MTLJ]

  54. Jiang, D.; Wang, JH-C. Tendinopathy and its treatment with platelet-rich plasma (PRP). Histology And Histopathology 28:1537-1546, 2013.[PubMed]

  55. Zhang, J.;Wang, JH-C. HGF mediates the anti-inflammatory effects of PRP on injured tendons. PloS One, 2013. 8(6): p. e67303.[PubMed]

  56. Zhang, J.; Wang, JH-C. The effects of mechanical loading on tendons - an in vivo and in vitro model study, PloS One, 2013. 8(8): p. e71740.[PubMed]

  57. Maeda, E.; Hagiwara, Y.; Wang, JH-C.; Ohashi, T. A new experimental system for simultaneous application of cyclic tensile strain and fluid shear stress to tenocytes in vitro.Biomedical Microdevices,2013. 15(6): p. 1067-75.[PubMed]

  58. Satish, L.; Johnson, S.; Raykha, C.; O'Gorman, D.B.; Gan, B.S.; Wang, JH-C.; Kathju, S. Increased CCT-eta expression is a marker of latent and active disease and a modulator of fibroblast contractility in Dupuytren's contracture. Cell Stress Chaperones, 18(4): 397-404,2013. [PubMed]

  59. Zhang, J.; Wang, JH-C. Human tendon stem cells better maintain their stemness in hypoxic culture conditions. PloS One,8(4): e61424.2013. [PubMed]

  60. Yang, Y.; Zhang, J.; Qian, Y.; Dong, S.; Huang, H.; Boada, F.E.; Fu, F.; Wang, JH-C. Superparamagnetic iron oxide is suitable to label tendon stem cells and track them in vivo with MR imaging, Annals of Biomedical Eng 2013. [PubMed]

  61. Ellman, M.B.; Kim, J.; An, H.S.; Chen, D.; Kc, R.; Li, X.; Xiao, G.Z.; Yan, D.; Suh, J.; van Wijnen, A.J.; Wang, JH-C.; Kim, S.G.; Im, H.J. Lactoferricin enhances BMP7-stimulated anabolic pathways in intervertebral disc cells. Gene, 524(2): 282-291.2013. [PubMed]

  62. Zhang, J.; Keenan, C.; Wang, JH-C. The effects of dexamethasone on human patellar tendon stem cells: implications for dexamethasone treatment of tendon injury, J Orthop Res,31(1): 105-110,2013. [PubMed]

  63. Zhang, J.; Wang, JH-C. BMP-2 mediates PGE2-induced reduction of proliferation and osteogenic differentiation of human tendon stem cells. J Orthop Res, 30(1):47-52, 2012. [PubMed]

  64. Zhang J, Pan T, Im H-J, Fu F, Wang, JH-C. Differential properties of human ACL and MCL stem cells may be responsible for their differential healing capacity. BMC Medicine, 9:68, 2011. [PubMed]

  65. Zhang J, Wang, JH-C. BMP-2 mediates PGE2-induced reduction of proliferation and osteogenic differentiation of human tendon stem cells. J Orthop Res, 2011. [PubMed]

  66. Liu ZM, Blattner SM, Tu Y, Tisherman R, Wang, JH-C., Kretzler M, Wu C. {alpha}-actinin-4 and CLP36 deficiencies contribute to podocyte defects in multiple human glomerulopathies. J Biol Chem, 286:30795-30805, 2011. [PubMed]

  67. Zhang J, Li B, Wang, JH-C. The role of engineered tendon matrix in the stemness of tendon stem cells in vitro and the promotion of tendon-like tissue formation in vivo. Biomaterials, 32:6972-6981, 2011. [PubMed]

  68. Shao, H.; Wang, JH-C.; Pollak, M.R.; Well, A. a-Actinin-4 is essential for maintaining the spreading, motility and contractility of fibroblasts. PLoS ONE 5(11):e13921, 2010.

  69. Zhou J, Kim HY, Wang, JH-C., Davidson LA. Macroscopic stiffening of embryonic tissues via microtubules, Rho-GEF, and assembly of contractile bundles of actyomyosin. Development, 137:2785-2794, 2010. [PubMed]

  70. Zhang J, Wang, JH-C. Platelet-rich plasma releasate promotes differentiation of tendon stem cells into active tenocytes. American Journal of Sports Medicine, 38:2477-2486, 2010. [PubMed]

  71. Zhang J, Pan T, Liu Y, Wang JH-C. Mouse treadmill running enhances tendons by expanding the pool of tendon stem cells (TSCs) and TSC-related cellular production of collagen. J Orthop Res, 2010. [PubMed]

  72. Satish L, Johnson S, Wang, JH-C., Post JC, Ehrlich GD, Kathju S. Chaperonin containing T-complex polypeptide subunit eta (CCT-eta) is a specific regulator of fibroblast motility and contractility. PLoS One, 2010. [PubMed]

  73. Zhang J, Wang, JH-C. Characterization of differential properties of rabbit tendon stem cells and tenocytes. BMC Musculoskeletal Disorders, 11:10, 2010. [PubMed]

  74. Li, X.; Ellman, M.; Muddasani, P.; Wang, JH-C.; Cs-Szabo1, G.; van Wijnen, A.J.; and Im, H.J. PGE2 and its cognate EP receptors control human adult articular cartilage homeostasis and are linked to the pathophysiology of osteoarthritis. Arthritis & Rheumatism, 60 (2)513-523, 2009.

  75. Zhang J, Wang, JH-C. Mechanobiological response of tendon stem cells: implications of tendon homeostasis and pathogenesis of tendinopathy. J Orthop Res, 2009. [PubMed]

  76. Zhang J, Wang, JH-C. High levels of PGE2 are produced in tendons subjected to repetitive mechanical loading and induce differentiation of tendon stem cells into non-tenocytes. J Orthop Res, 2009. [PubMed]

  77. Szczodry M, Zhang J, Lim CT, Davitt HL, Yeager T, Fu F, Wang, JH-C. Treadmill running exercise results in the presence of numerous myofibroblasts in mouse patellar tendons. J Orthop Res, 2009. [PubMed]

  78. Li B, Li F, Puskar KM, Wang JH-C. Spatial patterning of cell proliferation and differentiation depends on mechanical stress magnitude. J Biomech, 42:1622-627, 2009.[PubMed].

  79. Ekdahl M, Wang JH-C, Ronga M, Fu FH. Graft healing in anterior cruciate ligament reconstruction. Knee Surgery, Sports Traumatology, Arthroscopy, 16:935-4, 2008.[PubMed].

  80. Li B, Lin M, Tang Y, Wang B, Wang JH-C. A novel functional assessment of the differentiation of micropatterned muscle cells. Journal of Biomechanics, 41:3349-3353, 2008. [PubMed]

  81. Wang JH-C, Thampatty, BP. Mechanobiology of adult and stem cells. The International Review of Cell and Molecular Biology, 271:301-346, 2008. [PubMed].

  82. Li F, Li B, Wang QM, Wang, JH-C. Cell shape regulates collagen type I expression in human tendon fibroblasts. Cell Motil Cytoskel, 65:332-341, 2008. [PubMed].

  83. Li, F.; Wang, JH-C.; Wang, Q.M. Thickness shear mode acoustic wave sensors for characterizing the viscoelastic properties of cell monolayer. Sensors and Actuators B: Chemical 128: 399-406, 2008.

  84. Li B, Xie L, Starr ZC, Yang ZC, Lin J-S, Wang, JH-C. Development of Micropost Force Sensor Array with Culture Experiments for Determination of Cell Traction Forces. Cell Motility & Cytoskeleton, 64:509-18, 2007. [PubMed].

  85. Chen JX, Li HX, SundarRaj N, Wang, JH-C. Alpha-smooth muscle actin expression enhances cell traction force. Cell Motility & Cytoskeleton, 64:248-57, 2007.[PubMed].

  86. Thampatty BP, Li HX, Im HJ, Wang, JH-C. EP4 receptor regulates collagen type-I, MMP-1, and MMP-3 gene expression in human tendon fibroblasts in response to IL-1beta treatment, Gene, 386:154-161, 2007. [PubMed].

  87. Li, F.; Wang, JH-C.; Wang, Q.M. Monitoring cell adhesion by usingthickness shear mode acoustic wave sensors. Biosensors andBioelectronics 23(1): 42-50, 2007.

  88. Li B, Chen JX, Wang, JH-C. RGD peptide-conjugated poly(dimethylsiloxane) promotes adhesion, proliferation, and collagen secretion of human fibroblasts. J Biomed Mater Res, 2006. [PubMed].

  89. Thampatty BP, Wang, JH-C. A new approach to study fibroblast migration. Cell Motility & Cytoskeleton, 64:1, 2007. [PubMed].

  90. Yang ZC, Chen JX, Lin J-S, Wang, JH-C. Determining substrate displacement and cell traction fields - a new approach, J Theoretical Biology,242:607-616, 2006.[PubMed].

  91. Chen J, Iosifidis M, Zhu J, Tatarintsev I, Wang, JH-C. Vanadate ingestion enhances the organization and collagen fibril diameters of rat healing MCLs. Knee Surg Sports Traumatol Arthrosc, 14:750-755, 2006. [PubMed].

  92. Thampatty BP, Im HJ, Wang, JH-C. Leukotriene B4 at low dosage negates the catabolic effect of prostaglandin E2 in human patellar tendon fibroblasts. Gene, 372:103-109, 2006. [PubMed].

  93. Agarwal C, Britton ZT, Alaseirlis DA, Li Y, Wang, JH-C. Healing and normal fibroblasts exhibit differential proliferation, collagen production, alpha-SMA expression, and contraction. Ann Biomed Eng, 34:653-659, 2006. [PubMed].

  94. Yang GG, Im HJ, Wang, JH-C. Repetitive mechanical stretching modulates IL-1beta induced COX-2, MMP-1 expression, and PGE(2) production in human patellar tendon fibroblasts. Gene, 363:166-172, 2005. [PubMed].

  95. Alaseirlis, D.A., Li, Y., Cilli, F., Fu, F.H., Wang, JH-C. Decreasing inflammatory response of injured patellar tendons results in increased collagen fibril diameters. Connect Tissue Res, 46:3, 2005. [PubMed].

  96. Wang, JH-C., Yang G, Li Z. Controlling cell responses to cyclic mechanical stretching. Ann Biomed Eng, 33:337-342, 2005. [PubMed].

  97. Khan MH, Li Z, Wang, JH-C. Repeated exposure of tendon to prostaglandin-E2 leads to localized tendon degeneration. Clin J Sport Med, 15:27-3, 2005. [PubMed].

  98. Yang G, Crawford RC, Wang, JH-C. Proliferation and collagen production of human patellar tendon fibroblasts in response to cyclic uniaxial stretching in serum-free conditions. J Biomech, 37:1543-1550, 2004. [PubMed].

  99. Cilli F, Khan M, Fu F, Wang, JH-C. Prostaglandin E2 affects proliferation and collagen synthesis by human patellar tendon fibroblasts. Clin J Sport Med, 14:232-36, 2004. [PubMed].

  100. Wang, JH-C., Li Z, Yang G, Khan M. Repetitively stretched tendon fibroblasts produce inflammatory mediators. Clin Orthop Relat Res, 422:243-50, 2004. [PubMed].

  101. Campbell BH, Agarwal C, Wang, JH-C. TGF-beta1, TGF-beta3, and PGE(2) regulate contraction of human patellar tendon fibroblasts. Biomech Model Mechanobiol, 2:239-245, 2004. [PubMed].

  102. Cetin S, Ford HR, Sysko LR, Agarwal C, Wang, JH-C., Neal MD, Baty C, Apodaca G, Hackam DJ. Endotoxin inhibits intestinal epithelial restitution through activation of Rho-GTPase and increased focal adhesions. J Biol Chem, 279:24592-4600, 2004. [PubMed].

  103. Musahl V, Abramowitch S, Gilbert TW, Tsuda E, Wang, JH-C., Woo SL-Y. The use of porcine small intestinal submucosa to enhance the healing of the medial collateral ligament :a functional tissue engineering study in rabbits. J Orthop Res, 22:214 -220, 2004. [PubMed].

  104. Wang, JH-C., Yang G, Li Z, Shen W. Fibroblast responses to cyclic mechanical stretching depend on cell orientation to the stretching direction. J Biomech, 37:573-76, 2004. [PubMed].

  105. Peperzak KA, Gilbert TW, Wang, JH-C. A multi-station dynamic-culture force monitor system to study cell mechanobiology. Med Eng Phys, 26:355-58, 2004. [PubMed].

  106. Li Z, Yang G, Khan M, Stone D, Woo SL, Wang, JH-C. Inflammatory response of human tendon fibroblasts to cyclic mechanical stretching. Am J Sports Med, 32:435-440, 2004. [PubMed].

  107. Wang, JH-C.; Yang, G.; Li, ZZ.; Shen, W. Fibroblast responses tomechcanical stretching depends on cell orientation. J Biomech37:573-576, 2004.

  108. Wang, JH-C., Jia F, Yang GG, Yang SH, Stone D, Woo SL-Y. Cyclic mechanical stretching of human tendon fibroblasts increases the production of prostaglandin E2 and levels of cyclooxygenase expression: a novel in vitro model study. Connect Tissue Res, 44:128-133, 2003. [PubMed].

  109. Wang, JH-C., Jia F, Gilbert TW, Woo SL-Y. Cell orientation determines the alignment of cell-produced collagenous matrix. J Biomech, 36:97-102, 2003. [PubMed].

  110. Campbell BH, Clark WW, Wang, JH-C. A multi-station culture force monitor system to study cellular contractility. J Biomech, 36:137-140, 2003. [PubMed].

  111. Wang, JH-C., Goldschmidt-Clermont P, Jeremiah W, Yin, FC-P. Specificity of endothelial cell reorientation in response to cyclic mechanical stretching. J Biomech, 34:1563-1572, 2001. [PubMed].

  112. Neidlinger-Wilke C, Grood ES, Wang, JH-C., Brand R, Claes L. Cell alignment is induced by cyclic changes in cell length: studies of cells grown in cyclically stretched substrates. J Orthop Res, 19:286-293, 2001. [PubMed].

  113. Watanabe N, Celechovsky C, Niyibizi C, Wang, JH-C., Takai S, Woo SL-Y. The effect of growth factors on proliferation and matrix synthesis of fibroblasts from goat medial collateral ligament. J Musculoskeletal Res, 4:257-264, 2000.

  114. Wang, JH-C., Goldschmidt-Clermont P, Yin FC-P. Contractility affects stress fiber remodeling and reorientation of endothelial cells subjected to cyclic mechanical stretching. Ann Biomed Eng, 28:1165-1171, 2000. [PubMed].

  115. Wang, JH-C., Goldschmidt-Clermont P, Moldovan N, Yin FC-P. Leukotrienes and tyrosine phosphorylation mediate stretching-induced actin cytoskeletal remodeling in endothelial cells. Cell Motility & Cytoskeleton, 46:137-145, 2000. [PubMed].

  116. Wang, JH-C., Grood ES, Florer J, Wenstrup R. Alignment and proliferation of MC3T3-E1 osteoblasts in microgrooved silicone substrata subjected to cyclic stretching. J Biomech, 33:729-735, 2000. [PubMed].

  117. Wang, JH-C., Han JS, Ryu J, Rowen B. A new method for representation of articular surfaces using the influence surface theory of plates. J Biomech, 33:629-633, 2000. [PubMed].

  118. Wang, JH-C., Grood ES. The strain magnitude and contact guidance determine orientation response of fibroblasts to cyclic substrate strains. Conn Tissue Res, 41:29-36, 2000. [PubMed].

  119. Wang, JH-C. Substrate deformation determines actin cytoskeleton reorganization: A mathematical modeling and experimental study. J Theor Biology, 202:33-41, 2000. [PubMed].

  120. Wang, JH-C., Goldschmidt-Clermont, P.; Yin, FC-P. Contractility and reactive oxygen species affect actin cytoskeleton remodeling of the endothelial cell to mechanical stretching. Ann Biomed Eng 28: 1165-1171, 2000.

  121. Wang, JH-C., Ip W, Boissy R, Grood ES. Cell orientation response to cyclically deformed substrates: experimental validation of a cell model. J Biomech, 28:1543-1552, 1995.[PubMed].