Publications
Refereed Publications (Full List)

    Li, B.; Lin, M.; Tang, Y.; Wang, B.; and *Wang, JH-C.* A novel functional assessment of the differentiation of micropatterned muscle cells. /J Biomech/ 41:3349-3353, 2008.
  • Zhang J, Wang JH-C. Mechanobiological response of tendon stem cells: implications of tendon homeostasis and pathogenesis of tendinopathy. J Orthop Res, in press. [PDF] [PubMed]

  • Zhang J, Wang JH-C. High levels of PGE2 are produced in tendons subjected to repetitive mechanical loading and induce differentiation of tendon stem cells into non-tenocytes. J Orthop Res, in press (online available). [PDF] [PubMed]

  • Szczodry M, Zhang J, Lim CT, Davitt HL, Yeager T, Fu F, Wang JH-C. Treadmill running exercise results in the presence of numerous myofibroblasts in mouse patellar tendons. J Orthop Res, in press (online available). [PDF] [PubMed]

  • Li B, Li F, Puskar KM, Wang JH-C. Spatial patterning of cell proliferation and differentiation depends on mechanical stress magnitude. J Biomech 42(11):1622-1627, 2009. [PDF] [PubMed].

  • Ekdahl M, Wang JH-C, Ronga M, Fu F. Graft healing in anterior cruciate ligament reconstruction. Knee Surgery, Sports Traumatology, Arthroscopy 16(10):935-47, 2008 [PDF] [PubMed].
  • Wang JH-C, Thampatty BP. Mechanobiology of adult and stem cells. The International Review of Cell and Molecular Biology 271: 297-332, 2008 [PDF] [PubMed].
  • Li B, Lin M, Tang Y, Wang B, Wang JH-C. A novel functional assessment of the differentiation of micropatterned muscle cells. J Biomech 41:3349-3353, 2008. [PDF] [PubMed]

  • Li X, Ellman M, Muddasani P, Wang JH-C, Cs-Szabo G, van Wijnen AJ, and Im HJ. PGE2 and its cognate EP receptors control human adult articular cartilage homeostasis and are linked to the pathophysiology of osteoarthritis. Arthritis & Rheumatism (in press). [PDF] [PubMed]

  • Ekdahl M, Wang JH-C, Ronga M, Fu FH. Graft healing in anterior cruciate ligament reconstruction. Knee Surgery, Sports Traumatology, Arthroscopy (in press). [PDF] [PubMed].

  • Wang JH-C, Thampatty, BP. Mechanobiology of adult and stem cells. The International Review of Cell and Molecular Biology 271: 297-332, 2008. [PDF] [PubMed].

  • Li F, Li B, Wang QM, Wang JH-C. Cell shape regulates collagen type I expression in human tendon fibroblasts. Cell Motil Cytoskel 65(4):332-341, 2008 [PDF] [PubMed].

  • Li B, Xie L, Starr ZC, Yang ZC, Lin J-S, Wang JH-C. Development of Micropost Force Sensor Array with Culture Experiments for Determination of Cell Traction Forces. Cell Motility & Cytoskeleton 64(7):509-518, 2007 [PDF] [PubMed].

  • Chen JX, Li HX, SundarRaj N, Wang JH-C. Alpha-smooth muscle actin expression enhances cell traction force. Cell Motility & Cytoskeleton 64(4):248-257, 2007 [PDF] [PubMed].

  • Thampatty BP, Li HX, Im HJ, Wang JH-C. EP4 receptor regulates collagen type-I, MMP-1, and MMP-3 gene expression in human tendon fibroblasts in response to IL-1beta treatment, Gene 386(1-2):154-161, 2007 [PDF] [PubMed].

  • Li B, Chen JX, Wang JH-C. RGD peptide-conjugated poly(dimethylsiloxane) promotes adhesion, proliferation, and collagen secretion of human fibroblasts. J Biomed Mater Res A 79 (4):989-998, 2006 [PDF] [PubMed].

  • Thampatty BP, Wang JH-C. A new approach to study fibroblast migration. Cell Motility & Cytoskeleton 64 (1):1-5, 2006 [PDF] [PubMed].

  • Yang ZC, Chen JX, Lin J-S, Wang JH-C. Determining substrate displacement and cell traction fields - a new approach, J Theoretical Biology 242:607–616, 2006 [PDF] [PubMed].

  • Chen J, Iosifidis M, Zhu J, Tatarintsev I, Wang JH-C. Vanadate ingestion enhances the organization and collagen fibril diameters of rat healing MCLs. Knee Surg Sports Traumatol Arthrosc 14(8):750-755,2006 [PDF] [PubMed].

  • Thampatty BP, Im HJ, Wang JH-C. Leukotriene B4 at low dosage negates the catabolic effect of prostaglandin E2 in human patellar tendon fibroblasts. Gene 372:103-109, 2006 [PDF] [PubMed].

  • Agarwal C, Britton ZT, Alaseirlis DA, Li Y, Wang JH-C. Healing and normal fibroblasts exhibit differential proliferation, collagen production, alpha-SMA expression, and contraction. Ann Biomed Eng 34:653-659, 2006 [PDF] [PubMed].

  • Yang GG, Im HJ, Wang JH-C. Repetitive mechanical stretching modulates IL-1beta induced COX-2, MMP-1 expression, and PGE(2) production in human patellar tendon fibroblasts. Gene 363:166-172, 2005 [PDF] [PubMed].

  • Alaseirlis, D.A., Li, Y., Cilli, F., Fu, F.H., Wang, JH-C. Decreasing inflammatory response of injured patellar tendons results in increased collagen fibril diameters. Connect Tissue Res 46:12-17, 2005 [PDF] [PubMed].

  • Wang JH-C, Yang G, Li Z. Controlling cell responses to cyclic mechanical stretching. Ann Biomed Eng 33(3):337-342, 2005 [PDF] [PubMed].

  • Khan MH, Li Z, Wang JH-C. Repeated exposure of tendon to prostaglandin-E2 leads to localized tendon degeneration. Clin J Sport Med 15(1):27-33, 2005 [PDF] [PubMed].

  • Yang G, Crawford RC, Wang JH-C. Proliferation and collagen production of human patellar tendon fibroblasts in response to cyclic uniaxial stretching in serum-free conditions. J Biomech 37(10):1543-1550, 2004 [PDF] [PubMed].

  • Cilli F, Khan M, Fu F, Wang JH-C. Prostaglandin E2 affects proliferation and collagen synthesis by human patellar tendon fibroblasts. Clin J Sport Med 14(4):232-236, 2004 [PDF] [PubMed].

  • Wang JH-C, Li Z, Yang G, Khan M. Repetitively stretched tendon fibroblasts produce inflammatory mediators. Clin Orthop Relat Res (422):243-50, 2004 [PDF] [PubMed].

  • Campbell BH, Agarwal C, Wang JH-C. TGF-beta1, TGF-beta3, and PGE(2) regulate contraction of human patellar tendon fibroblasts. Biomech Model Mechanobiol 2(4):239-245, 2004 [PDF] [PubMed].

  • Cetin S, Ford HR, Sysko LR, Agarwal C, Wang JH-C, Neal MD, Baty C, Apodaca G, Hackam DJ. Endotoxin inhibits intestinal epithelial restitution through activation of Rho-GTPase and increased focal adhesions. J Biol Chem 279(23):24592-24600, 2004 [PDF] [PubMed].

  • Musahl V, Abramowitch S, Gilbert TW, Tsuda E, Wang JH-C , Woo SL-Y. The use of porcine small intestinal submucosa to enhance the healing of the medial collateral ligament – a functional tissue engineering study in rabbits. J Orthop Res 22(1):214-20, 2004 [PDF] [PubMed].

  • Wang JH-C, Yang G, Li Z, Shen W. Fibroblast responses to cyclic mechanical stretching depend on cell orientation to the stretching direction. J Biomech 37(4):573-6, 2004 [PDF] [PubMed].

  • Peperzak KA, Gilbert TW, Wang JH-C. A multi-station dynamic-culture force monitor system to study cell mechanobiology. Med Eng Phys 26(4):355-8, 2004 [PDF] [PubMed].

  • Li Z, Yang G, Khan M, Stone D, Woo SL, Wang JH-C. Inflammatory response of human tendon fibroblasts to cyclic mechanical stretching. Am J Sports Med 32(2):435-40, 2004 [PDF] [PubMed].

  • Wang JH-C, Jia F, Yang GG, Yang SH, Stone D, Woo SL-Y. Cyclic mechanical stretching of human tendon fibroblasts increases the production of prostaglandin E2 and levels of cyclooxygenase expression: a novel in vitro model study. Connect Tissue Res 44:128-133, 2003 [PDF] [PubMed].

  • Wang JH-C, Jia F, Gilbert TW, Woo SL-Y. Cell orientation determines the alignment of cell-produced collagenous matrix. J Biomech 36:97-102, 2003 [PDF] [PubMed].

  • Campbell BH, Clark WW, Wang JH-C. A multi-station culture force monitor system to study cellular contractility. J Biomech 12:137-140, 2002 [PDF] [PubMed].

  • Wang JH-C, Goldschmidt-Clermont P, Jeremiah W, Yin, FC-P. Specificity of endothelial cell reorientation in response to cyclic mechanical stretching. J Biomech 34(12):1563-1572, 2001 [PDF] [PubMed].

  • Neidlinger-Wilke C, Grood ES, Wang JH-C, Brand R, Claes L. Cell alignment is induced by cyclic changes in cell length: studies of cells grown in cyclically stretched substrates. J Orthop Res 19: 286-293, 2001 [PDF] [PubMed].

  • Watanabe N, Celechovsky C, Niyibizi C, Wang JH-C , Takai S, Woo SL-Y. The effect of growth factors on proliferation and matrix synthesis of fibroblasts from goat medial collateral ligament. J Musculoskeletal Res 4(4): 257-264, 2000.

  • Wang JH-C, Goldschmidt-Clermont P, Yin FC-P. Contractility affects stress fiber remodeling and reorientation of endothelial cells subjected to cyclic mechanical stretching. Ann Biomed Eng 28: 1165-1171, 2000 [PDF] [PubMed].

  • Wang JH-C, Goldschmidt-Clermont P, Moldovan N, Yin FC-P. Leukotrienes and tyrosine phosphorylation mediate stretching-induced actin cytoskeletal remodeling in endothelial cells. Cell Motility & Cytoskeleton 46: 137-145, 2000 [PDF] [PubMed].

  • Wang JH-C, Grood ES, Florer J, Wenstrup R. Alignment and proliferation of MC3T3-E1 osteoblasts in microgrooved silicone substrata subjected to cyclic stretching. J Biomech 33(6): 729-735, 2000 [PDF] [PubMed].

  • Wang JH-C, Han JS, Ryu J, Rowen B. A new method for representation of articular surfaces using the influence surface theory of plates. J Biomech 33(5): 629-633, 2000 [PDF] [PubMed].

  • Wang JH-C, Grood ES. The strain magnitude and contact guidance determine orientation response of fibroblasts to cyclic substrate strains. Conn Tissue Res 41(1): 29-36, 2000 [PDF] [PubMed].

  • Wang JH-C. Substrate deformation determines actin cytoskeleton reorganization: A mathematical modeling and experimental study. J Theor Biology 202: 33-41, 2000 [PDF] [PubMed].

  • Wang JH-C, Ip W, Boissy R, Grood ES. Cell orientation response to cyclically deformed substrates: experimental validation of a cell model. J Biomech 28(12): 1543-1552, 1995 [PDF] [PubMed].


    • Back to Publications