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Slide 7 of 25

Evaluation of the anemic patient is best served by a systemic evaluation of the clinical and laboratory findings together. First, is the patient truly anemic? Second, is the anemia acquired or inherited? Third is there evidence for blood loss? Fourth is there evidence for nutritional deficiency or malabsorption? Fifth, is there evidence for hemolysis? Sixth is there evidence for toxic exposure or drug ingestion that could cause bone marrow depression and anemia? Finally, dose the patient have chronic inflammatory disease, renal insufficiency, or cancer, each of which is associated with secondary mild anemias, the anemia of chronic disease