Department of Environmental and Occupational Health

Certifications Committees Honors Memberships Professional Activities Publications Research Reviewing

Publications - Luis A. Ortiz

Peer-Reviewed Publications (past 5 years)

  1. Ortiz LA, Dutrel M, Fattman C, Pandey AC, Torres G, Go K, Phinney DG. Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury. Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):11002-7. Epub 2007 Jun 14. PMID: 17569781

  2. Ortiz, L.A., Fattman, C., Dutreil, M., and Phinney, D. Murine Mesenchymal stem cells block T-cell proliferation via production of Interleukin 1 receptor antagonist. In Revision (PNAS).

  3. Reynolds, S.D*., Shen, H., Reynolds., PR., Betsuyaku, T., Pilewski, PM., Gambelli, F., DeGusippi, M., Ortiz, LA., B.R. Stripp. Molecular and Functional Properties of Lung Side Population Cells. Am J Physiol Lung Cell Mol Physiol. 2007 Jan 12; PMID: 17142352
    *Corresponding author

  4. Fattman CL, Gambelli F, Hoyle GW, Pitt BR, Ortiz LA. Epithelial expression of TIMP1 does not alter sensitivity to bleomycin-induced lung injury in C57BL/6 mice. Am J Physiol Lung Cell Mol Physiol. 2008 Jan 4; PMID: 18178676

  5. Fattman CL, Torres G, Brockway BL, Stripp BR, Ortiz LA. Remodeling of the Respiratory Unit in Silica-exposed Mice. Proc Am Thorac Soc. 2008 Apr;5(3):375. No abstract available. PMID: 18403369

  6. Creel, M., Studer, S.M., Schwerha, J., Harper, J., Ortiz, L.A., Ragin, C., and Taioli, E.  Gender differences in survival after lung transplantation: Implications for cancer etiology.  Transplantation.  2008.  85:8S:S64-S68. PMID: 18425040

  7. Weiss, D. J., Kolls, J.K., Ortiz, L.A., Panoskaltsis-Mortari, A., and Prockop, D.J.  Stem cells and cell therapies in lung biology and lung diseases.  Proc Am Thorac Soc. 2008 Jul 15;5(5):637-67. PMID: 18625757

  8. Di Giuseppe M, Gambelli F, Hoyle GW, Lungarella G, Studer SM, Richards T, Yousem S, McCurry K, Dauber J, Kaminski N, Leikauf G, Ortiz LA.  Systemic inhibition of NF-kappaB activation protects from silicosis.  PLoS ONE. 2009 May 25;4(5):e5689.  PMID: 19479048

  9. Martinu T, Palmer SM, Ortiz LA. Lung-resident mesenchymal stromal cells. A new player in post-transplant bronchiolitis obliterans syndrome? Am J Respir Crit Care Med. 2011 Apr 15;183(8):968-70. No abstract available.PMID: 21498820

  10. Reed DS, Smith L, Dunsmore T, Trichel A, Ortiz LA, Cole KS, Barry E. Pneumonic tularemia in rabbits resembles the human disease as illustrated by radiographic and hematological changes after infection. PLoS One. 2011;6(9):e24654. Epub 2011 Sep 13. PMID: 21931798

  11. Boregowda S, Krishnappa V, Chambers J, Lograsso PV, Lai WT, Ortiz LA, Phinney DG. Atmospheric Oxygen Inhibits Growth and Differentiation of Marrow-Derived Mouse Mesenchymal Stem Cells Via a p53 Dependent Mechanism: Implications for Long-Term Culture Expansion. Stem Cells. 2012 Feb 24. doi: 10.1002/stem.1069. PMID:22367737

Book Chapters and Invited Reviews (past 5 years)

  • Fattman, C., Torres, G., Brockway, B.L., Stripp, B.R., and Ortiz, L.A.  Remodeling of the respiratory unit in silica-exposed mice.  Proceedings of the American Thoracic Society 5(3): 375, 2008.

  • Martinu T, Palmer SM, Ortiz LA. Lung resident mesenchymal stromal cells. A new player in post transplant bronchiolitis obliterans syndrome? Am J Respir Crit Care Med. 2011 Apr 15;183(8):968-70

Abstracts (past 5 years)

  1. Fattman, C., Torres, G., Brockway, B.L., Stripp, B.R., and L.A. Ortiz. Remodeling of the respiratory unit in silica-exposed mice. Thomas L. Petty Aspen Lung Conference 50th annual meeting. Aspen, Colorado. June 2007.

  2. Ortiz, L.A., DiGiuseppe, M., and D.G. Phinney.   Interleukin 1 receptor antagonist mediates the anti-inflammatory effects of bone marrow derived mesenchymal stem cells. Am J Respir Crit Care Med. 177: A723, 2008.

  3. DiGiuseppe, M., Njah, J.M., Fazzi, F., Phinney, D.G., and Ortiz, L.A.  Osteopontin and Hyaluronate regulate mesenchymal stem cells migration. Am J Respir Crit Care Med. 177: A511, 2008.

  4. Ortiz, L.A., DiGiuseppe, M., Fazzi, F., and D.G. Phinney. S1P receptors mediate mesenchymal stem cell migration. Am J Respir Crit Care Med. 179: A3684, 2009.

  5. Ortiz, L.A., D. Winnica., Di Giuseppe, M., Fazzi, F., E. Sala., C. St. Croix., S. Watkins., and D.G. Phinney. Regulation of macrophage biology by mesenchymal stem cells (MSC) involves mitochondrial transfer. Am J Respir Crit Care Med. 179: A5281, 2010.

  6. Ortiz, L.A., D. Winnica., Di Giuseppe, M., Fazzi, F., E. Sala., C. St. Croix., S. Watkins., and D.G. Phinney. Regulation of macrophage biology by mesenchymal stem cells (MSC) involve mitochondrial transfer". 16th International Colloquium on Lung and Airway Fibrosis. Busselton, Western Australia, Australia, October, 2010.

  7. Ortiz, L.A., D. Winnica., Di Giuseppe, M., Fazzi, F., E. Sala., C. St. Croix., S. Watkins., and D.G. Phinney. The Mesenchymal stem cell (MSC) secretome involves mitochondrial transfer. Am J Respir Crit Care Med. A3768, 2011.

  8. G. Deiuliss, Di Giuseppe, M., Phinney, D.G., E. Sala., Kamisnki, N., and Ortiz, L.A. Differential expression of microRNA in mesenchymal stem cell derived exosomes. Am J Respir Crit Care Med. A3769, 2011.