Department of Environmental and Occupational Health

Certifications Committees Honors Memberships Professional Activities Publications Research Reviewing

Publications - Luis A. Ortiz

Peer-Reviewed Publications (past 5 years)

  1. Di Giuseppe M, Gambelli F, Hoyle GW, Lungarella G, Studer SM, Richards T, Yousem S, McCurry K, Dauber J, Kaminski N, Leikauf G, Ortiz LA.  Systemic inhibition of NF-kappaB activation protects from silicosis.  PLoS ONE. 2009 May 25;4(5):e5689.  PMID: 19479048

  2. Martinu T, Palmer SM, Ortiz LA. Lung-resident mesenchymal stromal cells. A new player in post-transplant bronchiolitis obliterans syndrome? Am J Respir Crit Care Med. 2011 Apr 15;183(8):968-70. No abstract available.PMID: 21498820

  3. Reed DS, Smith L, Dunsmore T, Trichel A, Ortiz LA, Cole KS, Barry E. Pneumonic tularemia in rabbits resembles the human disease as illustrated by radiographic and hematological changes after infection. PLoS One. 2011;6(9):e24654. Epub 2011 Sep 13. PMID: 21931798

  4. Boregowda S, Krishnappa V, Chambers J, Lograsso PV, Lai WT, Ortiz LA, Phinney DG. Atmospheric Oxygen Inhibits Growth and Differentiation of Marrow-Derived Mouse Mesenchymal Stem Cells Via a p53 Dependent Mechanism: Implications for Long-Term Culture Expansion. Stem Cells. 2012 Feb 24. doi: 10.1002/stem.1069. PMID:22367737

  5. Bein, K., Di Giuseppe, M., Mischler, S.E., Ortiz, LA; and Leikauf, G.D  Surfactant Protein B repression in pulmonary epithelial cells by LPS-stimulated macrophages via cytokines. Am J Respir Cell Mol Biol. 2013 Apr 3. [Epub ahead of print]     PMID:23590297

  6. Michael A. Matthay, Piero Anversa, Jahar Bhattacharya, Bruce K. Burnett, Harold A. Chapman, Joshua M. Hare, Derek J. Hei, Andrew M. Hoffman, Stella Kourembanas, David H. McKenna, Luis A. Ortiz, Harald C. Ott, William Tente, Bernard Thébaud, Bruce C. Trapnell, Daniel J. Weiss, Jason X.-J. Yuan, Carol J. Blaisdell.
    Cell Therapy for Lung Diseases, Report from an NIH-NHLBI Workshop November 13-14, 2012. Am J Respir Crit Care Med. 2013 May 28. [Epub ahead of print] PMID:23713908

  7. Mischler, S., Cauda, E., DiGiuseppe M., and Ortiz L.A.  A multi-cyclone sampling array for the collection of size-segregated occupational aerosols.  In press at Journal Occupational and Environmental Hygene.

  8. Fazzi F., Winnica D.E., Di Giuseppe M., Njah J., Go K., Sala E., St Croix C.M, Watkins   S.C., Tyurin V.A., Phinney D.G., Leikauf G.D., Kagan V.E., and Ortiz, LA.   TNFR1/Phox Interaction and TNFR1 Mitochondrial Translocation Thwarts Silica-  Induced Pulmonary Fibrosis. Accepted for Publication The Journal of Immunology

Book Chapters and Invited Reviews (past 5 years)

  • Martinu T, Palmer SM, Ortiz LA. Lung resident mesenchymal stromal cells. A new player in post transplant bronchiolitis obliterans syndrome? Am J Respir Crit Care Med. 2011 Apr 15;183(8):968-70

  • Weiss D., and Ortiz LA. Cell Therapy Trials for Lung Diseases: Progress and Cautions.    Am J Respir Crit Care Med. 2013 Jul 15;188(2):123-5. doi:      10.1164/rccm.2013020351ED. No abstract available. PMID:23855686

Abstracts (past 5 years)

  1. Ortiz, L.A., DiGiuseppe, M., Fazzi, F., and D.G. Phinney. S1P receptors mediate mesenchymal stem cell migration. Am J Respir Crit Care Med. 179: A3684, 2009.

  2. Ortiz, L.A., D. Winnica., Di Giuseppe, M., Fazzi, F., E. Sala., C. St. Croix., S. Watkins., and D.G. Phinney. Regulation of macrophage biology by mesenchymal stem cells (MSC) involves mitochondrial transfer. Am J Respir Crit Care Med. 179: A5281, 2010.

  3. Ortiz, L.A., D. Winnica., Di Giuseppe, M., Fazzi, F., E. Sala., C. St. Croix., S. Watkins., and D.G. Phinney. Regulation of macrophage biology by mesenchymal stem cells (MSC) involve mitochondrial transfer". 16th International Colloquium on Lung and Airway Fibrosis. Busselton, Western Australia, Australia, October, 2010.

  4. Ortiz, L.A., D. Winnica., Di Giuseppe, M., Fazzi, F., E. Sala., C. St. Croix., S. Watkins., and D.G. Phinney. The Mesenchymal stem cell (MSC) secretome involves mitochondrial transfer. Am J Respir Crit Care Med. A3768, 2011.

  5. G. Deiuliss, Di Giuseppe, M., Phinney, D.G., E. Sala., Kamisnki, N., and Ortiz, L.A. Differential expression of microRNA in mesenchymal stem cell derived exosomes. Am J Respir Crit Care Med. A3769, 2011.

  6. Ortiz, L.A., G. Deluliis, M. Di Giuseppe, E. Sala, D. Phinney, N. Kaminski. Micro RNA (miR) in mesenchymal stem cells (MSC) derived exosomes ameliorate pulmonary fibrosis.  Keystone meeting 2012.

  7. Njah, J, M. Di Giuseppe, E. Sala, D. Phinney, N. Kaminski, and Ortiz, L.A. Mesenchymal Stem Cells Use Extracellular Vesicles To Transfer Mitochondria And Micro RNAs To Modulate Macrophages In Lung Fibrosis.  International Society for Extracellular Vesicles (ISEV) 2013

  8. Ortiz, L.A., M. Di Giuseppe, D. Winnica, J. Njah, N. Kamisnki, E.Sala, and D. Phinney. Mesenchymal Stem Cells Extrude mitochondria and Shuttle micro RNAs to Modulate Macrophages in Lung Fibrosis.  Am J Respir Crit Care Med. A5427, 2013