Dr. Clara Gorodezky
Chief, Department of Immunogenetics
Instituto Nacional de Diagnostico Y Referencia Epidemiologicos
SSA Carpio 470-1
Mexico D.F. 11340
MEXICO

Telephone: 9011-525-3414569
FAX: 9011-525-5381884

Telephone: 9011-5273-114700 x 266
FAX: 9011-5273-172388
E-mail: arias@ibt.unam.mx

Dr. Arias is currently investigating different aspects of the biology of rotaviruses, with emphasis on the interactions of the virion with the host cell early in the infection cycle. Also, the study of the epidemiology of these viruses and the immune response they elicit in the host.

Five most recent publications and/or presentations:

1. Mendez, E. Cuadras M, Arias CF, Lopez S. Interactions between the two surface proteins of rotavirus may alter the receptor binding specificity of the virus. J Virol (in press, 1996)

2. Contreras JF, Menchaca GE, Padilla-Noriega L, Tamez RS, Greenberg HB, Lopez S, Arias CF. Heterogencity of VP4 neutralization epitopes among serotype P1A human rotavirus strains. Clin Diag Lab Immunol 2:506-508, 1995.

3. Fuentes-Panana EM, Lopez S, Gorziglia M, Arias CF. Mapping the hemagglutination domain of rotaviruses. J Virol 69:2629-2632, 1995.

4. Padilla-Noriega L, Dunn SJ, Lopez S, Greenberg HB, Arias CF. Identification of two indiependent neutralization domains on the VP4 trypsin cleavage products VP5 and VP8 of human rotavirus ST3. Virology 206:148-154, 1995.

5. Lopez S, Espinosa R, Greenberg HB, Arias CF. Mapping the subgroup epitopes of rotavirus protein VP6. Virology 204:153-162, 1994.

Telephone: 9011-525-2028200
FAX: 9011-525-5208868

Telephone: 9 011 52-73 114900
FAX: 9 011 52-73 17 2388
E-mail: ecalva@ibt.unam.mx

Dr. Calva is currently investigating the structure-function relationships and the genetic control of the expression of Salmonella typhi porins

Five most recent publications and/or presentations:

1. Verdugo-Rodriguez A, Lopez-Vidal Y, Puente JL, Ruiz-Palacios GM, and Calva E. Early diagnosis of typhoid fever by an enzyme immunoassay using Salmonella typhi out membrane protein preparations. European Journal of Clincal Microbiology and Infectious Disease.

2. Puente JL, Juarez D, Bobadilla M, Arias CF and Calva E. The Salmonella ompC gene: structure and use as carrier of heterologous sequences. Gene, 156:1-9, 1995.

3. Fernandez-Mora M, Oropeza R, Puente JL and Calva E. Isolation and characterization of ompS1 a novel Salmonella typhi outer membrane protein-encoding gene. Gene, 158:67-72, 1995.

4. Martinez-Flores I, Bustamante VH, Puente JL and Calva E. Cloning and characterization of the Salmonella typhi omp R and envZ genes. Asia-Pacific Journal of Molecular Biology and Biotechnology, 3:135-144, 1995.

5. Bustamante VH, Puente JL, Sanchez-Lopez F, Bobadilla M and Calva E. Identification of Campylobacter jejuni and C. coli using the rpoB gene and a cryptic DNA fragment from C.jejuni. Gene, 165:1-8, 1995.

Telephone: 9011-525-6559675
FAX: 9011-525-5130010
E-mail:jcalva@mailer.main.conacyt.mx

Dr. Calva is currently investigating the epidemiology of enteropathogens and the pharmacoepidemiology of antimicrobials

Five most recent publications and/or presentations:

1. Journal of Clinical Epidemiology, 47(2), 147-156, 1994.

2. Pediatr. Infect. Dis J., 13:597, 1994.

3. Soc. Sci. Med (in press), 1996.

4. J. Lab. Clin. Med. (in press), 1996.

5. J. Med. Virol (in press), 1996.

Telephone: 9011-525-6276900, ext. 6940, 6941
FAX: 9011-525-7610952

Dr. Rivera is currently investigating giardiasis and amoebiasis

Five most recent publications and/or presentations:

1. Cedillo-Rivera R, Munoz O. In vitro susceptibility of Giardia lamblia to albendazole, mebendazole and other chemoterapeutic agents. J Med Microbiol 37:221-224, 1992.

2. Chavez B, Cedillo-Rivera R, Martinez-Palomo A. Giardia lamblia: ultrastructural study of the in vitro effect of benzimidazoles. J Protozool 39:510-515, 1992.

3. Cedillo-Rivera R, Ramirez A, Munoz O. A rapid colorimetric assas with the tetrazolium salt MMT and phenazine methosulfate (PMS) for viability of entamoeba histolytica. Arch Med Res 23:59-61, 1992.

4. O'Shea-Alvarez S, Gonzalez-Robles A, Chavez B, Cedillo-Rivera R. Ultrastructural localization of giartdia lamblia antigens by human IgG and IgA. Arch Med Res 25:407-412, 1994.

5. Chavez B, Gonzaleeeeeeeeez Mariscal L, Cedillo-Rivera R, Martinez-Palomo A. Giardia lamblia in vitro cytophatic effect of human isolates. Exp Parasitol 80:133-138, 1995.

Telephone: 9011-525-6232427 and 6160146
FAX: 9011-525-616-2346

Dr. Cravioto is currently investigating:

Epidemiology of diarrhoeal disease caused by different strains of escherichia coli, associationof virulence factors from gram negative bacteria (e coli and haemophi lus influenzae) to humandisease, cellular surface antigens (outer membrane proteins) and e xtracellular components(enterotoxin).

Five most recent publications and/or presentations:

1. Nataro JP, Savarino SJ, Yikang D, Cookson S, Cravioto A, Cuerra LD, Levin NM, TacketCO. Heterogeneity of enteroaggregative escherichia coli virulence demonstrated in volunteers. J Infect Dis. 171:465©468, 1995.

2. Gomez de Leon P, Molinari JL, Cabrera R, Gomez©Barreto D, Cravioto J, Cravioto A. Serum response to outer membrane proteins of haemophilus influenzae type b in Mexicanchildren with or without evidence of invasive disease. Immunol Infect Dis. 5:238©24 3,1995.

Ô coli. J Infect Dis (in press, 1996).

4. Serichantalergs O, Nirdnoy W, Cravioto A, LeBron C, Wolf M, Svennerholm AM, ShlimD, Hoge CW, Echeverria P. Coli surface antigens (cs) associated with enterotoxigenicescherichia coli (ETEC) isolated from persons with travelers diarrhea (TD) in Asia. J InfectDis. (submitted, 1996).

5. Navarro©Garcia F, Villaseca JM, Eslava C, Lopez©Revilla R, Cravioto A. In vitro effectsof a high molecular weight heat©liable enterotoxin of enteroaggregative escherichia coli,antigenically related to cholera toxin. Infect Immun. (submitted, 1996).

Telephone: 9011-525-3411101 and 3414389
FAX: 9011-525-3413264

E-mail: flisser@servidor.unam.mx

Dra. Flisser is currently investigating cysticercosis and taeniasis due to
taenia solium

Five most recent publications and/or presentations:

1. Flisser A, Sarti E, Sarti R, Schabtz PM. Effect of praziquantel on protozoan parasites. Lancet, 345:316, 1995.

2. Plancarte A, Fexas M, Flisser A. Reactivity in ELISA and dot blot of purified GP24 an immunodominant antigen of Taenia solium, for the diagnosis of human neurocysticercosis. International Journal for Parasitology, 24:733-738, 1994.

3. Schantz PM, Sarti E, Plancarte A, Wilson M, Criales JL, Roberts J, Flisser A. Community-based epidemiological investigations of Cysticercosis due to Taenia solium: Comparison of serological screening test and clinical findings in two populations in Mexico. clinical Infectious Disease, 18:879-885, 1994.

4. Flisser A, Plancarte A, Avila G. Aplicacion de metodos de diagnostico de cisticercosis y teniasis a estudios epidemiologicos. Rev. Fac. Med. UNAM 37:82-91, 1994.

5. Flisser A. Taeniasis and Cysticercosis due to taenia solium. Chapter 4 in Tsieh Sun, MD (ed.). Progress in Clinical Parasitology, 4:77-116, 1994.

Telephone: 9011-525-6223891 & 6161602
FAX: 9011-525-622381
E-mail: carranca@servidor.unam.mx

Dr. Carranca is currently investigating:

The role of human papillomavirus (HPV) and ras oncogenes in the development of cervical cancer.

Five most recent publications and/or presentations:

1. Cid A, Auewarakul P, Garica Carranca A, Ovselovich R, Gaissert H, Gissman L. Cell-type- specifi activity of the human papillomavirus type 18 upstream regulatory region in transgenic mice and its modulation by tetradecanoyl phorbol acctate and glucocorticoids. J Virol 67:6742- 6752, 1993.

2. Berumen J, Casas L, Segura E, Amerzcua JL, Garcia Carranca A. Genome amplification of human papillomavirus types 16 and 18 in cervical carcinomas is related to the retention of E1/E2 genes. Int. J. Cancer 56:640-645, 1994.

3.Penaloza R, Garcia Carranca A, Ceras T, Alvarez C, Berumen J, Zavala C and Salamanca F. Frequency of haplotypes in the beta globin gene cluster in a selected sample of the Mexican population. Am J Human Biol 7:45-49, 1995.

4. Miranda E, Santana C, Rojas E, Hernandez S, Ostrosky P, Garcia Carranca A. Induced mitotic death of HeLa cells by abnormal expression of c-H-ras. Mutation Res (in press, 1995).

5. Medina O, Morales N, Yaniv M, Garcia Carranca A, Thierry F. A single element mediates glucocorticoid hormone response of HPV18 with no functional interactions with AP1 or HBRM. Virology (in press, 1996).

Telephone: 9011-525-6661473
FAX: 9011-525-3414880

Telephone: 9011-525-6232469
FAX: 9011-525-6232459 & 6232382
E-Mail: begomez@servidor.unam.mx

Dr. Gomez is currently investigating in vitro models of respiratory syncytial virus persistence infection.

Five most recent publications and/or presentations:

1. Tirado R, Sarmiento RE, Bustos J, Thompson O, Gomez B. Occurrence of respiratory syncytial virus subtypes in Mexican infants with lower respiratory tract disease. Archives of Medical Research 26:121-126, 1995.

2. Yamamoto L, Mejia E, Lopez RM, Gallardo E, Gomez B. Susceptibility to rubella infection in females at high risk: immune protection associated to population density. Tropical and Geographical Medicine 47(6):1-4, 1995.

3. Guerrero MA, Ortega E, Alfaro A, Ortega V, Gomez B. Effects of macrophages immune functions by respiratory syncytial virus persitence. IV Latin American Congress of Immunology. March 4-8, 1996. Zacatecaz, Zac. Mexico.

4. Sarmiento RE, Romero M, Tirado R, Gomez B. Respiratory syncytial virus genome expression in persitent infected macrophages. IV Latin American Congress of Immunology. March 4-8, 1996. Zacatecaz, Zac. Mexico.

5. Romero MV, Ravize CH, Alonso RM, Gomez B. Comparison of the RFLP intergenic map of proteins F and G of respiratory syncytial virus strains. IV Latin American Congress of Immunology. March 4-8, 1996. Zacatecaz, Zac. Mexico.

Telephone: 9011-52-73175391
FAX: 9011-52-73111148

Five most recent publications and/or presentations:

1. Lazcano©Ponce EC, Hernandez©Avila M, Lopez©Carrillo L, Alonso de Ruiz P, TorresªLobaton A, Gonzalez©Lira G, Romieu J. Factores de riesgo reproductivo e historia de vidaÔ Revista de Investigacion Clinica 47(5):377ª385, 1995

2. Romieu I, Hernandez©Avila M, Lazcano©Ponce E, Lopez©Carrillo L, Romero©Jamie R. Breast cancer and lactation history in Mexican women. Amer J of Epid 143(6):(in press),1995

3. Romieu I, Carreon T, Lopez L, Paluzuelos E, Rios C, Manuel Y, Hernandez©Avila M. Environmental, urban lead exposure and blood lead levels in children of Mexico City. Enviromental Health Perspecives 103(11):(in press), 1995

4. Romieu I, Meneses F, Sienra J, Huerta J, Ruiz©Velasco S, White M, EtzelR, HernandezªAvila M. Effects of urban air pollutants on emergency visits for childhood asthma in MexicoCity. Amer J Epid 141(6):546©553, 1995.

5. Frumkin H, Hernandez©Avila M, Espinosa©Torres F. The maquiladoras: a case study of freetrade zones. Inter J of Occupat and Environ Health 1(2):96©109, 1995

Telephone: 9011-525-5537860
FAX: 9011-525-5537860

Telephone: 9011-525-5732437
FAX: 9011-525-5133722
Email: hnicolina@mailer.buzon.conacyt.mx

Dr. Nicolini is currently investigating genetics of psychiatric disorders association studies with candidate genes obsessive--compulsive disorders

Five most recent publications and/or presentations:

1. Perez B, Desviat L, Die M, Cornejo V, Chamoles N, Nicolini H, Ugarte M. Presence of the mediterranean PKU mutation IVS10 in Latin America. Human Molecular Genetics, 2(8): 1289-1290, 1993.

2. Nicolini H, Cruz C, Camarena B, Merino MF, Bilbao G, Vela M, Velazquez A, Perez B, Desviat L, Ugarte M. Molecular analysis of the PAH gene in Mexican Phenylketonuric patients.Archives of Medical Research, 26(1): 53-57, 1995.

3. Orozco B, De la Fuente JR, Nicolini H. Tratamiento del Trastorno Obsesivo-Compulsivo, Experiencia del Instituto Mexicano de Psiquiatria en 73 pacientes. Salud Mental, 18(1): 1-13, 1995.

4. Mickalonis L, Orozco B, Pacz F, De la Fuente JR, Nicolini H. Estudio de Simulacion por computadora para la cleccion de familias utiles en el mapeo de genes. Salud Mental, 18(2): 11- 17, 1995.

5. Cruz C, Camarena B, Eroza V, Mejia J, Paez F, De la Fuente JR, Nicolini H. The dopamine D2 receptor gene Taq 1 polymorphism and alcoholism in a Mexican population. Archives of Medical Research, 26(4): 421-426, 1995.

Telephone: 9011-525-341-4953
FAX: 9011-525-6024497

Telephone: 9 011 525 752 0677, ext. 5328
FAX: 9 011 525 586 6290 / 525 752 0590

Telephone: 9011-525-259-2471
FAX: 9011-525-550-0048

Telephone: 9011-525-7091 & 525-7092
FAX: 9011-525-7093
E-mail: adolfo.martinex.direccion.inf.cinvestav.mx

Dr. Palomo is currently investigating Giardiasis, Amibiasis, Trichomoniasis

Five most recent publications and/or presentations:

1. Martinez-Palomo A (Editor). Vido y obra de Pasteur por Manual
Martinez-Baez con un apendice: en Defensa de Pasteur por el Dr. Adolfo
Martinez-Palomo. El Colegio Nacional/Fondo de Culrura Economica,
Mexico, 558 pp, 1995.

2. Campos Rodriguez R, Shibayama Salas M, Pacheco Yepes J, Martinez Palomo A,
Tustusmi V. Passive immunization during experimental amebic liver-abscess
development. Parasitology Research 81:86-88, 1995.

3. Chavez B, Gonzalez-Mariscal L, Cedillo Rivera R, Martinez Palomo A. Giardia
lamblia: in vitro cytopathic effect of human isolates. Experimental
Parasitology 80:133-138.

4. Chavez B, Martinez-Palomo A. Ciardia lamblia: freeze-fracture ultrastructure of
the ventral disc plasm membrane. Journal of Eukaryotic Microbiology
42:136-141, 1995.

5. Gonzalez-Robles A, Lazaro-Haller A, Espinosa-Cantellano M, Anaya- Velazquez F,
Martinez-Palomo A. Trichomonas vaginalis: Ultrastructural bases of the cytopathic
effect. Journal of Eukaryotic Microbiology 42:641-651, 1995.Ô Secretario de Salud
Lieja #7, 1er Piso
Col. Juarez
Mexico DF, 06696
Mexico

Telephone: 9011-525-553-1353
FAX: 9011-525-553-7917

Telephone: 9011-9173-110111 Ext. 2432
FAX: 9011-9173-175485

Telephone: 9011-525-6276900
FAX: 9011-525-7610952

Dr. Salamanca is currently investigating:

Molecular genetics, cytogenetics, cancer genetics and population genetics

Five most recent publications and/or presentations:

1. Genet Counc 5:175-178, 1994.

2. Pennloza R, Garcia A, Ceras T, Anaya C, Berumen J, Zavala C, Salamanca F. Frequency of haplotypes in the beta globin cluster gene in a selected sample of the Mexican population. Amer J Hum Biol 7:45-49, 1995.

3. Lisker R, Ramirez E, Penaloza R, Salamanca F. Red cell acid phosphatase types and polymorphisms in Merida, Oaxaca, Leon and Saltillo, Mexico. Hum Biol 66:1103-1109, 1994.

4. Salamanca F, Armendares S. Development of human genetics in Mexico. Arch Med Res 26:55-62, 1995.

5. Salamanca F, Coral R, Penaloza R, Arenas D, Gonzalez M, Barrientos C, Buentello L. Molecular studies of Mendelian disorders, embryonic neoplasias and polymorphisms in selected samples of the general population. A contribution to the genetic characterization of the Mexican population. Arch Med Res 26:69-75, 1995.

Telephone: 9011-525-73112344
FAX: 9011-525-73111156

Telephone: 9011-525-7610333 & 7614957
FAX: 9011-525-7618530

Telephone: 9011-525-5930922 & 5933738
FAX: 9011-525-5930786

Telephone: 9011-525-5930922 & 5930824
FAX: 9011-525-5930786

Telephone: 9011-525-6063558
FAX: 9011-525-6063489

Telephone: 9011-525-5204302
FAX: 9011-525-5208868