Department of Environmental and Occupational Health

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Kiflai Bein - Publications

Abstracts

Bein, K. and Evans, D.R. In vitro and in vivo expression in mammalian cells of a full-length hamster CAD cDNA. The FASEB J. Atlanta 1991; Apr 21-25: 4816.

Bein, K. and Evans, D.R. Expression of a full-length cDNA encoding the multifunctional protein CAD in mammalian cells. The Genes and Enzymes of Pyrimidine Biosynthesis Conference. Glasgow, Scotland 1992; Sep 12-14.

Husain, M., Jiang, L., Bein, K., Ware, J.A., Alper, S.L., Simons, M. and Rosenberg, R.D. Dominant negative c-myb constructs lower intracellular calcium levels and slow cell cycle progression in vascular smooth muscle cells. Supplement to Circulation, 92: #1422. Anaheim, California 1995; November 13-16.

Bein, K. and Simons, M. Binding of thrombospondin 1 and 2 type 1 repeats to and regulation of metalloproteinase 2. The American Society for Cell Biology 39th Annual Meeting: Washington, D.C. 1999. Dec 11-15.

Bein, K. and Simons, M. Thrombospondins 1 and 2 Inhibit activation of pro-metalloproteinases 2 and 9 enzymes. Supplement to Circulation, 102: #839. New Orleans, Louisiana 2000; November 12-15.

Bein, K. Characterization of His6-S peptide-MBP fusion tag produced using the baculoviral expression system. 42 nd American Society for Cell Biology Annual Meeting San Francisco 2002, Dec 14-18 Molecular Biology of the Cell Vol 13 supplement

Bein, K. TGF-B1-induced alteration of capillary tube patterning. North American Vascular Biology Organization Meeting. Pacific Grove, CA 2004. Endothelium 10: 360-61.

Books and Book Chapters

Paola Grandi, Kiflai Bein, Costas G. Hadjipanayis, Darren Wolfe, Xandra O.Breakefield and Joseph C. Glorioso. Application of HSV-1 Vectors to the Treatment of Cancer. In Viral Therapy of Cancer, edited by Harrington, K.J., Vile, R.G., and Pandha, H. Chichester, England: Hoboken, NJ; John Wiley & Sons. June, 2008, Page 19.

Journal Articles

  1. Bein, K., Simmer, J.P., and Evans, D.R. Molecular cloning of a cDNA encoding the amino end of the multifunctional protein CAD and analysis of the flanking region of the CAD gene. J. Biol. Chem. 1990; 266: 3791-3799. PMID: 1671675


  2. Evans, D.R., Bein, K., Guy, H.I., Liu, X., Molina, A. and Zimmermann, B.H. CAD gene sequence and the domain structure of the mammalian multifunctional protein. Biochem. Soc. Trans. 1993; 21: 186-91. PMID: 8095469


  3. Husain, M., Bein, K., Jiang, L., Alper, S., Simons, M. and Rosenberg, R.D. c-Myb-dependent cell cycle progression and Ca2+ storage in cultured vascular smooth muscle cells. Circulation Research 1997; 80: 617-626. PMID: 9130442


  4. Husain, M., Jiang, L., See, V., Bein, K., Simons, M., Alper, S., and Rosenberg, R.D. Regulation of vascular smooth muscle cell proliferation by plasma membrane Ca 2+ ATPase. American J Physiol. 1997; 272: C1947-C1959. PMID: 9227424


  5. Bein, K., Husain, M., Ware, J.A., Mucenski, M.L., Rosenberg , R.D. and Simons, M. c-Myb function in fibroblasts. J. Cellular Physiol. 1997; 173: 319-326. PMID: 9369944


  6. Bein, K. Ware, J.A. and Simons, M. Myb-dependent regulation of thrombospondin 2 expression: role of mRNA stability. J Biol. Chem. 1998; 273: 21423-21429. PMID: 9694906


  7. Bein, K. and Simons, M. Thrombospondin type 1 repeats Interact with Matrix Metalloproteinase 2: regulation of metalloproteinase activity. J. Biol. Chem. 2000; 275: 32167-32173. PMID: 10900205


  8. * Bein, K., Odell-Fiddler, E.T., Drinane, M. Role of TGF-{beta}1 and JNK signaling in capillary tube patterning. Am J Physiol Cell Physiol. 2004; 287: C1012-C1022. *Please note that the first author is the main author. PMID: 15201140


  9. Odell-Fiddler, E.T. and Bein, K. Transforming growth factor B1-induced inhibition or stimulation of endothelial cell motility is mediated through an ALK5/p160Rock-dependent mechanism. 2006.


  10. Odell-Fiddler, E.T. and Bein, K. 2007. The dual effects of TGF-B1 on endothelial cell motility are dictated by pericellular context. Molecular and Cellular Biology (Submitted).


  11. Li H, Baskaran R, Krisky DM, Bein K, Grandi P, Cohen JB, Glorioso JC. Chk2 is required for HSV-1 ICP0-mediated G2/M arrest and enhancement of virus growth. Virology. 2008 Mar 3. PMID: 18321553


  12. Bein K, Wesselkamper SC, Liu X, Dietsch M, Majumder N, Concel VJ, Medvedovic M, Sartor M, Henning LN, Venditto C, Borchers MT, Barchowsky A, Weaver TE, Tichelaar JW, Prows DR, Korfhagen TR, Hardie WD, Bachurski CJ, Leikauf GD.  Surfactant Associated Protein B is Critical to Survival in Nickel-induced Injury in Mice.  Am J Respir Cell Mol Biol. 2009 Jan 8. [Epub ahead of print].  PMID: 19131640


  13. Koustav Ganguly, Martin Depner, Cheryl Fattman, Kiflai Bein, Tim D. Oury, Scott C. Wesselkamper, Michael Thomas Borchers, Martina Schreiber, Fei Gao, Erika von Mutius, Michael Kabesch, George D. Leikauf, and Holger Schulz.  Superoxide dismutase 3, extracellular (SOD3) variants and lung function.  Physiol. Genomics. 2009 May 13;37(3):260-7. Epub 2009 Mar 24. PMID: 19318538

Joint Presentations

Leikauf, G.D., Concel, V., Liu, P., Dietsch, M., Bein, K., Majumder, N., Jang, A-S., Borchers, M.T., Tichelaar, J.A., Prows, D.R., Hardie, W., Korfhagen, T., and You, M. Functional Genomics of Chemical Induced Acute LUng Injury. Countermeasures Against Chemical Threats. Washington, D.C., 2008.

Presentations

Year
Title
1992 Expression of a full-length cDNA encoding the multifunctional protein CAD in mammalian cells. An International Conference on the Genes and Enzymes of Pyrimidine Biosynthesis, Glasgow, Scotland; Sep 12-14.
1997 The proto-oncoprotein c-Myb-dependent repression of thrombospondin 2 expression. NHLBI 5 th Annual Cardiovascular Minority Supplement Awardee Session, Orlando, Fl, Nov 9.
2000 Thrombospondins 1 and 2 Inhibit Activation of Pro-Metalloproteinases 2 and 9 Enzymes. American Heart Association, New Orleans, Louisiana ; Nov 14.
2004 TGF-B1-induced alteration of capillary tube patterning. NAVBO Workshop on Vascular Development. Pacific Grove, CA. Feb 4.
2008 Leikauf, G.D., Concel, V., Liu, P., Dietsch, M., Bein, K., Majumder, N., Jang, A-S., Borchers, M.T., Tichelaar, J.A., Prows, D.R., Hardie, W., Korfhagen, T., and You, M. Functional genomics of chemical induced acute lung injury. Countermeasures against chemical threats. Washington D.C. 2008.