Lab Publications



Functional near-infrared spectroscopy (fNIRS) of brain function during active balancing using a video game system. Karim H, Schmidt B, Dart D, Beluk N, Huppert T. Gait Posture. 2011 Nov 9.

Quantification of the cortical contribution to the NIRS signal over the motor cortex using concurrent NIRS-fMRI measurements. Gagnon L, Yücel MA, Dehaes M, Cooper RJ, Perdue KL, Selb J, Huppert TJ, Hoge RD, Boas DA. Neuroimage. 2011 Oct 21.


A random-effects model for group-level analysis of diffuse optical brain imaging. Abdelnour F, Huppert T. Biomed Opt Express. 2010 Nov 30;2(1):1-25.

Hierarchical Bayesian regularization of reconstructions for diffuse optical tomography using multiple priors. Abdelnour F, Genovese C, Huppert T. Biomed Opt Express. 2010 Oct 6;1(4):1084-1103.

Neuroimaging with near-infrared spectroscopy demonstrates speech-evoked activity in the auditory cortex of deaf children following cochlear implantation. Sevy AB, Bortfeld H, Huppert TJ, Beauchamp MS, Tonini RE, Oghalai JS. Hear Res. 2010 Dec 1;270(1-2):39-47.


Topographic localization of brain activation in diffuse optical imaging using spherical wavelets. Abdelnour F, Schmidt B, Huppert TJ. Phys Med Biol. 2009 Oct 21;54(20):6383-413.

Sensitivity of neural-hemodynamic coupling to alterations in cerebral blood flow during hypercapnia. Huppert TJ, Jones PB, Devor A, Dunn AK, Teng IC, Dale AM, Boas DA. J Biomed Opt. 2009 Jul-Aug;14(4):044038.

Real-time imaging of human brain function by near-infrared spectroscopy using an adaptive general linear model. Abdelnour AF, Huppert T. Neuroimage. 2009 May 15;46(1):133-43.

HomER: a review of time-series analysis methods for near-infrared spectroscopy of the brain. Huppert TJ, Diamond SG, Franceschini MA, Boas DA. Appl Opt. 2009 Apr 1;48(10):D280-98. Review.

Exploring neuro-vascular and neuro-metabolic coupling in rat somatosensory cortex. Mesquita RC, Huppert TJ, Boas DA. Phys Med Biol. 2009 Jan 21;54(2):175-85.


Direct estimation of evoked hemoglobin changes by multimodality fusion imaging. Huppert TJ, Diamond SG, Boas DA. J Biomed Opt. 2008 Sep-Oct;13(5):054031.

Estimating cerebral oxygen metabolism from fMRI with a dynamic multicompartment Windkessel model. Huppert TJ, Allen MS, Diamond SG, Boas DA. Hum Brain Mapp. 2009 May;30(5):1548-67.

Diffuse optical tomography of pain and tactile stimulation: activation in cortical sensory and emotional systems. Becerra L, Harris W, Joseph D, Huppert T, Boas DA, Borsook D. Neuroimage. 2008 Jun;41(2):252-9.

Increased left prefrontal activation during staring/mutism episodes in a patient with resistant catatonic schizophrenia: a near infrared spectroscopy study. Grignon S, Forget K, Durand M, Huppert T. Cogn Behav Neurol. 2008 Mar;21(1):41-5.

A vascular anatomical network model of the spatio-temporal response to brain activation. Boas DA, Jones SR, Devor A, Huppert TJ, Dale AM. Neuroimage. 2008 Apr 15;40(3):1116-29.


Near-infrared spectroscopy measurement of the pulsatile component of cerebral blood flow and volume from arterial oscillations. Themelis G, D'Arceuil H, Diamond SG, Thaker S, Huppert TJ, Boas DA, Franceschini MA. J Biomed Opt. 2007 Jan-Feb;12(1):014033.


Quantitative spatial comparison of diffuse optical imaging with blood oxygen level-dependent and arterial spin labeling-based functional magnetic resonance imaging. Huppert TJ, Hoge RD, Dale AM, Franceschini MA, Boas DA. J Biomed Opt. 2006 Nov-Dec;11(6):064018.

A multicompartment vascular model for inferring baseline and functional changes in cerebral oxygen metabolism and arterial dilation. Huppert TJ, Allen MS, Benav H, Jones PB, Boas DA. J Cereb Blood Flow Metab. 2007 Jun;27(6):1262-79.


Diffuse optical imaging of the whole head. Franceschini MA, Joseph DK, Huppert TJ, Diamond SG, Boas DA. J Biomed Opt. 2006 Sep-Oct;11(5):054007.

Diffuse optical tomography system to image brain activation with improved spatial resolution and validation with functional magnetic resonance imaging.  Joseph DK, Huppert TJ, Franceschini MA, Boas DA. Appl Opt. 2006 Nov 1;45(31):8142-51.

A temporal comparison of BOLD, ASL, and NIRS hemodynamic responses to motor stimuli in adult humans.  Huppert TJ, Hoge RD, Diamond SG, Franceschini MA, Boas DA.  Neuroimage. 2006 Jan 15;29(2):368-82.

Dynamic physiological modeling for functional diffuse optical tomography.  Diamond SG, Huppert TJ, Kolehmainen V, Franceschini MA, Kaipio JP, Arridge SR, Boas DA.  Neuroimage. 2006 Mar;30(1):88-101.


Physiological system identification with the Kalman filter in diffuse optical tomography. Diamond SG, Huppert TJ, Kolehmainen V, Franceschini MA, Kaipio JP, Arridge SR, Boas DA.  Med Image Comput Comput Assist Interv. 2005;8(Pt 2):649-56.

Simultaneous recording of task-induced changes in blood oxygenation, volume, and flow using diffuse optical imaging and arterial spin-labeling MRI. Hoge RD, Franceschini MA, Covolan RJ, Huppert T, Mandeville JB, Boas DA.  Neuroimage. 2005 Apr 15;25(3):701-7.