Tentative syllabus for the Biological Chemistry Core Course

Tentative Syllabus for the Biological Chemistry I Core Course, Chem 2810

	Topic	Homework Probs	Number of 75 m lectures
Week 1	Introduction and orientation		0.2
Week 1	Chemical properties of amino acids, oligopeptides, and proteins		2
Week 2	Bioynthesis of proteins		2
Week 3	Physical interactions that determine the properties of proteins		2
Week 4	Conformational properties of polypeptide chains		1
Week 4	The folded conformation of globular proteins		1
Week 5	Proteins in solution		2
Week 6	Integral membrane proteins and ion channels		2
Week 7	Ion channel proteins		1
Oct 18	First Exam
Week 8	Interactions between proteins and other molecules		2
Week 9 and 10	Enzyme kinetics, transistion state theory, induced fit,data analysis		4
Week 11	Catalytic antibodies		2
Week 12 and 13	Special topics / Biosynthesis of small molecules		4
Dec 6	Second Exam

Textbook: Proteins- Structure and Molecular Properties, Second Edition, Thomas E. Creighton, Freeman, NY, 1993 ISBN 0-7167-7030-X

Grades:

There will be two exams, one midterm and one at the end of the term. Each will count for 30% of the grade. There will be weekly homework assignments based on literature exercises, in total counting for 30% of the grade. In addition, each student will have the opportunity to present a discussion of a research paper for an additional 10 points. A satisfactory discussion will be awarded 10 points, while a less than satisfactory presentation will be forgiven and the student will be asked to repeat the process. Guidelines for the presentation will be given during the first lecture. An abstract must be prepared and turned into the instructor, as well as passed to the class. The abstract should be constructed in the following way:

Your name
The date of the presentation
An abstract of the answer, in the format: Hypothesis, Experimental Design, Experimental Results, Interpretation. Include citations to any ournal articles, books, etc. that you used.

Recitation: There will be a weekly recitation/help session on Monday Evening in Room 621, or at another time and place chosen by the class and the professor that week. Except for the weekend before an exam, the recitation will cover only the immediately preceding week's material. Recitations given on weekends before exams will cover all of the material on the exam.