Department of Environmental and Occupational Health

James P. Fabisiak - Publications

Refereed Articles - Past 5 years

  1. Shvedova, A.A., Fabisiak, J.P., Kisin, E.R., Murray, A., Roberts, J., Antonini, J., Kommineini, C., Reynolds, J., Barchowsky, A., Castranova, V., and Kagan, V.E. Sequential exposure to carbon nanotubes and bacteria enhances pulmonary inflammation and infectivity. Am. J. Respir. Cell Mol. Biol., 38:579-590, 2008. PMID: 16751226


  2. Brant, K., and Fabisiak, J.P. Nickel alteration of TLR-2-dependent chemokine profiles in human lung fibroblasts is dependent on cyclooxygenase-2 (COX-2). Am. J. Respir. Cell Mol. Biol., 38:591-599, 2008. PMID: 18096868


  3. Brant, K.A. and Fabisiak, J.P. Nickel and the microbial toxin, MALP-2, stimulate proangiogenic mediators from human lung fibroblasts via a HIF-1a and COX-2-mediated pathway. Toxicol. Sci., 107:227-237, 2009. PMID: 18832182


  4. Gao, F. Brant, K.A., Ward, R.M., Cattley, R.T., Barchowsky, A., Brant, K., and Fabisiak, J.P. Multiple protein kinase pathways mediate amplified IL-6 release by human lung fibroblasts co-exposed to nickel and TLR-2 agoinst, MALP-2. Toxicol. Appl. Pharmacol. 2010 Sep 1;247(2):146-57. Epub 2010 Jun 17. PubMed PMID: 20600219


  5. Fabisiak JP, Medvedovic M, Alexander DC, McDunn JE, Concel VJ, Bein K, Jang AS, Berndt A, Vuga LJ, Brant KA, Pope-Varsalona H, Dopico RA Jr, Ganguly K, Upadhyay S, Li Q, Hu Z, Kaminski N, Leikauf GD. Integrative metabolome and transcriptome profiling reveals discordant energetic stress between mouse strains with differential sensitivity to acrolein-induced acute lung injury. Mol Nutr Food Res. 2011 Aug 8. doi: 10.1002/mnfr.201100291. PubMed PMID: 21823223


  6. Leikauf GD, Pope-Varsalona H, Concel VJ, Liu P, Bein K, Berndt A, Martin TM, Ganguly K, Jang AS, Brant KA, Dopico RA Jr, Upadhyay S, Di YP, Li Q, Hu Z, Vuga LJ, Medvedovic M, Kaminski N, You M, Alexander DC, McDunn JE, Prows DR, Knoell DL, Fabisiak JP. Integrative Assessment of Chlorine-induced Acute Lung Injury in Mice. Am J Respir Cell Mol Biol. 2012 Mar 23. PubMed PMID: 22447970


  7. Brant, K.A., and Fabisiak, J.P.  Role of HIF1a and CREB1 in synergistic release of IL8 by PGE2 and nickel in lung fibroblasts.  Am. J. Respir. Cell Mol. Biol., 2013, In Press. Epub ahead of print.


  8. Leikauf, G.D., Concel, V.J., Bein, K., Liu, P., Berndt, a., Martin, T.M., Ganguly, K., ,Jang, A.S., Brant, K.A., Dopico, R.A., Jr., Upadhyay, S., Cario, C.L., Di, Y.P., Vuga, L.J., Kostem, E., Eskin, E., You, M., Kaminski, N., Prows, D.R., Knoell, D.L., Fabisiak, J.P.  Functional genomic assessment of phosgene-induced lung injury in mice.  Am. J. Respir. Cell Mol. Biol., 2013, In Press.  Epub ahead of print.