Biological Sciences 1540
Computational Biology
Fall Term 2016-2017

Class Schedule

Reading assignments pertain to Introduction to Bioinformatics, 4th Ed.
Date Lecture topic Instructor Reading Assignment
29-Aug Intro/Molecular Biology Review Eric Polinko Ch1: 1-10 & 21-22
31-Aug Genomes, Genomics, and the Human Genome Project EP

Ch2: 59-62 & 88-90

02-Sep **LAB** The Internet, Networking, & Unix EP
05-Sep ***NO CLASS - LABOR DAY***
07-Sep Genomics EP

Ch2: 64-88

09-Sep (hw#1 due @ noon)

**LAB** NCBI & UniProt
EP

 

12-Sep

(Project Version 1 due @ 9am)

Genomics Cont'd

EP

Ch2: 88-100
Ch9: 328-334

14-Sep Past, Present, and Future of DNA Sequencing Dan Russell
16-Sep

(hw#2 due @ noon)

Visualization & Organization of Genomic Data

Miler Lee


19-Sep **Lab** Genome Browsers ML  
21-Sep Proteomics EP Ch2: 62-64
23-Sep

**Lab** - BLAST & ClustalΩ

EP

 

26-Sep  Proteomics Cont'd & Systems Biology EP Ch1: 50
Ch7: 282-283
Ch9: 335-340
28-Sep Biological Databases EP Ch3: 104-109
Ch4: 144-152
30-Sep Sequence Database Searching - Scoring Matrices

(hw#3 due @ noon)

EP

Ch5: 176-186
03-Oct Sequence Database Searching - Pairwise Sequence Alignment

(Project Version 2 due @ 9am)

EP Ch5: 187-193
05-Oct Sequence Database Searching - BLAST & Evaluation EP Ch5: 194-196
07-Oct

(hw#4 due @ noon)

**LAB** - High Performance Computing at SaM

Kim Wong
10-Oct RNAseq Analysis Ansuman Chattopadhyay Ch2: 62-64
12-Oct

**LAB** - CLCBio Genomics Workbench

AC
14-Oct (hw#5 due @ noon)

**LAB** - CLCBio Genomics Workbench

AC


17-Oct ***FALL BREAK - CLASS ON TUESDAY***
18-Oct

Integrative Large-scale Genomics Projects

Miler Lee  
19-Oct

Multiple Sequence Alignment

ESP Ch5: 196-197
21-Oct

**LAB** - Jalview

(& pssm lab?)
EP
24-Oct

(Project Version 3 due @ 9am)

Position-Specific Scoring Matrices
EP Ch1: 30-38
Ch5: 198-202
26-Oct Exam Review (&/or lecture catch-up/ketchup) EP  
28-Oct (hw#6 due @ noon?)

Development of a Learning Electronic Medical Record (EMR) System
Andrew King Ch3: 133-141
31-Oct EXAM I EP  
2-Nov

Intro to Protein Structure

Joel Rosenbaum Ch10: 298-304, 322-328
4-Nov **LAB** - VMD EP
7-Nov Solving Protein Structure via X-ray Crystallography JR
9-Nov

**LAB** - Coot

JR
11-Nov

Introduction to Biomolecular Simulation

** In 103 Clapp Hall **

Jacob Durrant Ch6: 255-257
14-Nov

Biomolecular Simulation

** In 103 Clapp Hall **

JD Ch6: 255-257
16-Nov **LAB**- Preparing a Simulation Model using VMD JD VMD
18-Nov

**LAB** - Running a Simulation using NAMD

JD NAMD
21-Nov **LAB**- Simulation Analyses
JD  
23/25-Nov ***NO CLASS - THANKSGIVING***
28-Nov
Scientific Consultant(s) @ BioTeam, Inc.

Adam Kraut & Adam Marko BioTeam
30-Nov

Connectomics & Brain Imaging

Project Part IV due

Art Wetzel & Greg Hood

fMRI Overview
2-Dec Exam review EP Ch5: 181-186
5-Dec Lead Bioinf Scientist @ UPMC Presby Keith Callenberg
7-Dec EXAM II  
9-Dec **Field Trip to MMBioS!**
Creating Stereoscopic 3D Movies
Art Wetzel, Greg Hood, & Jacob Czech MMBioS
12-17 Dec

FINAL ==> Project Presentations

Three alternative days/times (TBA)





Last Updated: 25 August 2016
Question or Comments: epolinko@pitt.edu
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