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Refereed Journal Papers

2013

Johnson NR and Wang Y. Controlled delivery of Sonic hedgehog morphogen and its potential for cardiac repair. PLoS One, In Press.

Park D, Shah V, Rauck B, Friberg TR, and Wang Y. An anti-angiogenic reverse thermal gel as a drug delivery system for age-related wet macular degeneration. Macromol. Biosci, In Press.

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Chu H, Chen C-W, Huard J, and Wang Y. The effect of a heparin-based coacervate of fibroblast growth factor-2 on scarring in the infarcted myocardium. Biomaterials, 34(6):1747-56.

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Johnson N and Wang Y. Controlled delivery of heparin-binding EGF-like growth factor yields fast and comprehensive wound healing. J. Control. Release, 166(2):124-9.

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Park D, Larson AM, Klibanov AM, Wang Y. Antiviral and antibacterial polyurethanes of various modalities. App. Biochem. Biotechnol., 169(4): 1134-1146.

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Hagandora K, Gao J, Wang Y, Almarza AJ. Poly (glycerol sebacate): a novel scaffold material for temporomandibular joint disc engineering. Tissue Eng., 19(5-6): 729-737.

2012

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Bae H, Chu H, Edalat F, Cha JM, Sant S, Kashyap A, Ahari AF, Kwon CH, Nichol JW, Manoucheri S, Zamanian B, Wang Y, and Khademhosseini A. Development of functional biomaterials with micro- and nanoscale technologies for tissue engineering and drug delivery applications. J Tissue Eng Regen Med. , 6: 1-14.

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Chu H, and Wang Y. Therapeutic Angiogenesis: Controlled Delivery of Angiogenic Factors. Therapeutic Delivery, 3: 693-714.

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You Z, Wang Y. A Versatile Synthetic Platform for a Wide Range of Functionalized Biomaterials. Advanced Functional Materials, 22: 2812-20.

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Wu W, Allen R, and Wang Y. Fast Degrading Elastomer Enables Rapid Remodeling of a Cell-Free Synthetic Graft into a Neo-Artery. Nature Medicine, 18: 1148-1153.

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Jeffries EM and Wang Y. Biomimetic Micropatterned Multi-channel Nerve Guides by Templated Electrospinning. Biotechnology and Bioengineering, 109: 1571-82.

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You Z, Bi X, and Wang Y. Fine Control of Polyester Properties via Epoxide-opening Polymerization Using Monomers Carrying Diverse Functional Groups. Macromolecular Bioscience, 12: 822-9.

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Chu H, Gao J, and Wang Y. Design, synthesis, and biocompatibility of an arginine-based polyester. Biotechnology Progress., 28: 257-264

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You Z, Bi X, Fan X, and Wang Y. A functional polymer designed for bone tissue engineering. Acta Biomaterialia., 8: 502-510

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You Z, Bi X, Jeffries EM, and Wang Y. A biocompatible, metal-free catalyst and its application in microwave-assisted synthesis of functional polyesters. Polymer Chemistry, 3:384-389.

2011

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Allen, R and Wang Y. Rapid Self-Assembly of Tubular Arterial Media Layer from Smooth Muscle Cells in Transient Fibrin Gel.J Tissue Sci Eng. 2:105e.

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Chu H, Gao J, Chena C, Huard J, and Wang Y. Injectable fibroblast growth factor-2 coacervate for persistent angiogenesis. PNAS.

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Zern BJ, Chu H, Osunkoya AO, Gao J, and Wang Y. A Biocompatible Arginine-based Polycation. Adv. Func. Mater., 21: 434-440

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Chu H, Johnson NR, Mason NS, and Wang Y. A [polycation:heparin] complex releases growth factors with enhanced bioactivity. J. Control. Release, 150, 157-163

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Park D, Wu W, and Wang Y. A functionalizable reverse thermal gel based on a polyurethane / PEG block copolymer. Biomaterials, 32:777-786

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Crapo P and Wang Y. Hydrostatic Pressure Independently Increases Elastin and Collagen Co-expression in Small-diameter Engineered Arterial Constructs. J. Biomed. Mat. Res., 96(4):673-81

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Lee K-W, Stolz DB, and Wang Y. Substantial Expression of Mature Elastin in Arterial Constructs. Proc. Natl. Acad. Sci. U.S.A., 108:2705-10

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Wu W, Allen R, Gao J, and Wang Y Artificial Niche Combining Elastomeric Substrate and Platelet Guided Vascular tissue formation of Bone Marrow Mononuclear Cells. Tissue Eng

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Gumera C, Rauck B, and Wang Y. Materials for Central Nervous System Regeneration: Bioactive Cues. J. Mater. Chem., 21, 7033 - 7051

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Lee K-W and Wang Y: Elastomeric PGS Scaffolds in Arterial Tissue Engineering. http://www.jove.com/details.stp?id=2691 doi: 10.3791/2691. J. Vis. Exp. 50

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Wilson ME, Kota N, Kim YT, Wang Y, Stolz DB, LeDuc P, and Ozdoganlar BO. Fabrication of Circular Microfluidic Channels by Combining Mechanical Micromilling and Soft Lithography. Lab Chip. 11, 1550-1555


2010

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Crapo PM and Wang Y. Small Intestinal Submucosa Gel as a Potential Scaffolding Material for Cardiac Tissue Engineering. Acta Biomater., 2091-2096

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Crapo PM and Wang Y. Physiologic Compliance In Engineered Small-Diameter Arterial Constructs Based On An Elastomeric Substrate. Biomaterials, 31: 1626-1635

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You Z, Cao H, Gao J, Shin, PH, Day BW, and Wang Y. A functionalizable polyester with free hydroxyl groups and tunable physiochemical and biological properties. Biomaterials, 31: 3129-3138

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Zern BJ, Chu H, and Wang Y. Control growth factor release using a self-assembled [polycation:heparin] complex. PLoS ONE, 5, e11017. doi:10.1371

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Marsano A, Maidhof R, Wan LQ, Wang Y, Gao J, Tandon N, and Vunjak-Novakovic G. Scaffold stiffness affects the contractile function of three dimensional engineered cardiac constructs, Biotechnol. Prog., 26: 1382-1390


2009

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Secasanu V, Giardina C, and Wang Y. A novel electrospinning target for improved yield of uniaxially aligned fibers. Biotechnol. Prog. 25: 1169-1175

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Lee EJ, Vunjak-Novakovic G, Wang Y, and Niklason LE. A biocompatible endothelial cell delivery system for in vitro tissue engineering. Cell Transplant. 18: 731-743


2008

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Gao J, Crapo PM, Nerem R, and Wang Y. Co-Expression of Elastin and Collagen Leads to Highly Compliant Engineered Blood Vessels. J. Biomed. Mat. Res. 85A: 1120-1128

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Crapo PM, Gao J, and Wang Y. Seamless Tubular Poly(glycerol sebacate) Scaffolds: High-yield Fabrication and Potential Applications. J. Biomed. Mat. Res. 86: 354-363

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Radisic M, Park H, Salazar-Lazaro JE, Wang Y, Langer R, Freed LE, and Vunjak-Novakovic G. Pretreatment of Synthetic Elastomer Scaffolds by Cardiac Fibroblasts Improves Engineered Heart Tissue. J. Biomed. Mat. Res. 86: 713-724

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Radisic M, Marsano A, Maidhof R, Wang Y, and Vunjak-Novakovic G. Cardiac tissue engineering using perfusion bioreactor systems. Nat. Protoc. 3: 719-738


2007

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Gumera C and Wang Y. Modulating neuronal responses by controlled integration of acetylcholine-like functionalities in biomimetic polymers. Adv. Mater. 19: 4404-4409

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Gao J, Ensley A, Nerem R, and Wang Y. Poly (glycerol sebacate) Supports the Proliferation and Phenotypic Protein Expression of Primary Baboon Vascular Cells. J. Biomed. Mat. Res. 83: 1070-1075

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Kim YM, Gao J, Zern B, and Wang Y. Biofunctional materials for Nerve Regeneration. Mater. Sci. Forum, 539: 547-550

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Sales VL, Engelmayr GC, Gottlieb D, Johnson JA, Gao J, Wang Y, Sacks MS, and Mayer JE. Protein Precoating of Elastomeric Tissue-Engineering Scaffolds: Extracellular Matrix Formation and Phenotypic Changes of Circulating Endothelial Progenitor Cells. Circ. Res., 99: e35


2006

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Gao J, Crapo PM, and Wang Y. Macroporous Elastomeric Scaffolds with Extensive Micropores for Soft Tissue Engineering. Tissue Eng., 12: 917-925

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Gao J, Kim YM, Coe H, Zern B, Sheppard B, and Wang Y. A Neuro-inductive Biodegradable Material Based on Dopamine. Proc. Natl. Acad. Sci. U.S.A., 103: 16681-16686

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Radisic M, Park H, Chen F, Wang Y, Dennis R, Langer R, Freed LE, and Vunjak-Novakovic G. Biomimetic Approach to Cardiac Tissue Engineering: Oxygen Carriers and Channeled Scaffolds. Tissue Eng., 12: 1-15

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Bettinger CJ, Weinberg E, Wang Y, Borenstein J, and Langer R. Three-dimensional Microfluidic Tissue Engineering Scaffolds Using a Flexible Biodegradable Polymer. Adv. Mater. 18: 165-169


2005

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Fidkowski C, Kaazempur-Mofrad MR, Borenstein J, Vacanti JP, Langer R, and Wang Y. Endothelialized Microvasculature Based on a Biodegradable Elastomer. Tissue Eng., 11: 302-309

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Haaga J, Exner A, Wang Y, Stowe N, and Tarcha PJ. Combined Tumor Therapy by Using Radiofrequency Ablation and 5-FU-Laden Polymer Implants: Evaluation in Rats and Rabbits. Radiology, 911-918

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Sundback CA, Shyu JY, Wang Y, Faquin WC, Langer R, Vacanti JP, and Hadlock TA. Biocompatibility Analysis of Poly(glycerol sebacate) as a Nerve Guide Material. Biomaterials, 26: 5454-5464


1996-2004

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Ijima H, Wang Y, and Langer R. Spheroid Formation and Expression of Liver Specific Functions of Primary Rat Hepatocytes Co-cultured with Bone Marrow Cells. Biochem. Eng. J., 20: 223-228

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Wang Y, Kim YM, and Langer R. In vivo Degradation characteristics of Poly(glycerol sebacate). J. Biomed. Mat. Res. 66A: 192-197

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Wang Y, Ameer GA, Sheppard BJ, and Langer R. A Tough Biodegradable Elastomer. Nat. Biotechnol., 20: 602-606

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Wang Y, DuBois JL. Hedman B, Hodgson KO, and Stack TDP Catalytic Galactose Oxidase Models: Biomimetic Cu(II)-Phenoxyl-Radical Reactivity. Science, 279: 537-540

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Wang Y and Stack, TDP. Galactose Oxidase Model Complexes: Catalytic Reactivities. J. Am. Chem. Soc., 118: 13097-13098