Name: Robert L. Duda, Ph.D
Bob Duda works in the laboratory of Dr.
Roger Hendrix where he is Co-PI on the grant that funds the lab's major grant to study bacteriophage assembly.
Laboratory members include Bonnie La, Jianfei Hua, Josh Maurer, Jacob Spiegel, Jennifer Hess and Moulika Baireddy, as well as sometimes resident collaborators from James Conway's Lab, Alexis Huet and Patricial Campbell plus Welkin Pope Chambers, Charles Bowman and Dan Russel in the PBI Genome Center.
Research interests: Our lab uses bacteriophages as model systems to learn how proteins assemble into complex biological structures. The structural components of phages are particularly appropriate because they are large enough that we can visualize them using electron microscopy and detect them using simple gel assays, but simple enough that we know all of the genes required to produce them and can easily make mutations and study their effects. Three easily studied parts of phages are tails, tail fibers, and capsids.
Experimental systems: My research focuses mainly on capsids and in particular the capsid of E. coli phage HK97. Other projects include looking at the structure and assembly of the capsids of some additional phages, including D3, phi1026b, XP10 and P1. We also have ongoing studies of bacteriophage Lambda tail assembly and bacteriophage Lambda side tail fiber assembly.
Click here to learn more about the ongoing research in the lab.