This set of research projects explores variation in global agenda-setting. Why have transnational advocacy networks (TANs) in the human security area mobilized around some issues (such as HIV-AIDS, landmines, child soldiering, and violence against women) but not others (such as forced conscription, stigma against children born of war rape, or fuel-air explosives)? With the support of the National Science Foundation’s Human and Social Dynamics Initiative, our goal is to operationalize the human security network, document the existing human security agenda, and explore reasons for variation in issue advocacy.