The Center for Education and Drug Abuse Research (CEDAR), funded by the National Institute on Drug Abuse (grant number 2 P50 DA05605) since 1989, has the overarching mission of delineating the origins and developmental pathways to substance use disorder (SUD). Biobehavioral processes and environmental factors are comprehensively assessed prior to first exposure to alcohol and drugs, and subsequently during the period of substance use behavior leading ultimately to a diagnosis of substance use disorder (SUD). Employing a prospective paradigm enables clarifying the factors influencing the transition from no use to substance use to SUD. From the practical perspective, upon completion of this longitudinal investigation, the individual risk for succumbing to SUD can be quantitatively specified across different stages of development. Youth who are at high risk for SUD can thus be accurately and objectively identified for prevention intervention.
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