NAME: Barbara Wendeborn Brandom

BUSINESS Children's Hospital of Pittsburgh

ADDRESS: Department of Anesthesiology

3705 Fifth Avenue at DeSoto Street

Pittsburgh, PA 15213-2583

BUSINESS (412) 692-5260 E-MAIL: BWB@vms.cis.pitt.edu

PHONE: or BWB+@pitt.edu

FAX: (412)-692-8658

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UNDERGRADUATE:

1968-1972 Douglass College B.A., 1972

New Brunswick, NJ Biological Science

GRADUATE:

1972-1976 University of Pennsylvania M.D., 1976

Philadelphia, PA

POST-GRADUATE:

1976-1977 University Health Center Hospitals Internship, Flex

Pittsburgh, PA D. Ryan Cook, M.D.

1977-1979 University Health Center Hospitals Residency, Anesthesiology

Pittsburgh, PA D. Ryan Cook, M.D.

1979-1980 Children's Hospital of Pittsburgh Ped/Anes Fellowship

University Health Center Peter M. Winter, M.D.

Pittsburgh, PA D. Ryan Cook, M.D.

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ACADEMIC:

1980-1986 University of Pittsburgh Assistant Professor

School of Medicine of Anesthesiology

Department of Anesthesiology

Pittsburgh, PA

1986-1992 University of Pittsburgh Associate Professor

School of Medicine of Anesthesiology

Department of Anesthesiology

Pittsburgh, PA

1992-Present University of Pittsburgh Professor

School of Medicine of Anesthesiology

Department of Anesthesiology

Pittsburgh, PA

NON-ACADEMIC:

1980-Present Children's Hospital of Pittsburgh Staff Anesthesiologist

Department of Anesthesiology

Pittsburgh, PA

1984-Present Presbyterian-University Hospital Staff Anesthesiologist

Department of Anesthesiology

Pittsburgh, PA

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SPECIALTY CERTIFICATION:

1977 National Board of Medical Examiners, Parts I, II and III

10/3/1980 Certified, Diplomate, American Board of Anesthesiology,
certificate number: 9,648

MEDICAL OR OTHER PROFESSIONAL LICENSURE:

1976-Present Pennsylvania Medical License, MD-019788-E

1976-Present American Society of Anesthesiologists

1976-Present International Anesthesia Research Society

1976-Present Pennsylvania Society of Anesthesiologists

1976-Present Society of Neurosurgical Anesthesia and Neurologic Supportive Care

1976-1991 Society of Cardiovascular Anesthesia

1985-Present American Academy of Pediatrics, Section on Anesthesiology

1987-Present American Trauma Society

1987-Present Society for Pediatric Anesthesia

1987-1993 Society for Education in Anesthesia

1988 (elected to) Association of University Anesthetists

1993 - Present International Association for the Study of Pain

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1988 Elected to the Association of University Anesthetists

1989-1990 The Dr. Leroy Harris Award for Excellence in Teaching of the

University of Pittsburgh Department of Anesthesiology and
Critical Care Medicine

1994-1995 The Best Doctors in America, 2nd edition, Woodward/White, Inc., 129 First Ave SW, Aiken, SC, p. 42, 1994.

1996-1997 The Best Doctors in America: Northeast Region, Woodward/White, Inc., 129 First Ave SW, Aiken, SC, 1996.

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Refereed Articles.

1. Cook DR, Brandom BW, Shiu G, Wolfson B: The inspired median effective dose, brain concentration of anesthesia, and cardiovascular index for halothane in young rats. Anesth Analg 60:182-185, 1981.

2. Cook DR, Brandom BW: Enflurane, halothane, and isoflurane inhibit removal of 5-hydroxytryptamine from pulmonary circulation. Anesth Analg 61:671-675, 1982.

3. Brandom BW, Brandom RB, Cook DR: Uptake and distribution of halothane in infants and adults in vivo measurements and computer simulations. Anesth Analg 62:404-410, 1983.

4. Brandom BW, Rudd GD, Cook DR: Clinical pharmacology of atracurium in pediatric patients. Brit J Anaesth 55:117S-121S, 1983.

5. Brandom BW, Woelfel SK, Cook DR: Clinical pharmacology of atracurium in infants. Anesth Analg 63:309-312, 1984.

6. Alifimoff JK, Kaul S, Brandom BW, Cook DR: Enflurane, halothane and isoflurane do not inhibit angiotensin converting enzyme activity. Can Anesth Soc J 32:351-357, 1985.

7. Stiller RL, Brandom BW, Cook DR: Determination of atracurium in plasma by high-performance liquid chromatography. Anesth Analg 64:58-62, 1985.

8. Brandom BW, Cook DR, Woelfel SK, Rudd GD: Atracurium infusion requirements in children during halothane, isoflurane, and narcotic anesthesia. Anesth Analg 64:471-476, 1985.

9. Pollock BG, Perel JM, Brandom BW, Antelman S, Kupfer DJ: Understanding the response lag to tricyclics I. Application of pulse-loading regimens with intravenous clomipramine. Psychopharmacology 22:214-219, 1986.

10. Brandom BW, Stiller RL, Cook DR, Woelfel SK, Chakravorti S, Lai A: Pharmacokinetics of atracurium in anesthetized infants and children. Br J Anesth 58:1210-1213, 1986.

11. Sarner JB, Brandom BW, Cook DR, Dong ML, Horn MC, Woelfel SK, Davis PJ, Rudd GD, Foster VJ, McNulty BF: Clinical pharmacology of doxacurium chloride (BW A938U) in children. Anesth Analg 67:303-306, 1988.

12. Davis PJ, Stiller RL, Cook DR, Brandom BW, Davin-Robinson KA: Pharmacokinetics of sufentanil in adolescent patients with chronic renal failure. Anesth Analg 67:268-271, 1988.

13. Weber S, Brandom BW, Powers DM, Sarner JB, Woelfel SK, Cook DR, Foster VJ, McNulty BF, Weakly JN: Mivacurium chloride (BW B1090U) induced neuromuscular blockade during nitrous oxide-isoflurane and nitrous oxide-narcotic anesthesia in adult surgical patients. Anesth Analg 67:495-499, 1988.

14. Sarner JB, Brandom BW, Woelfel SK, Dong ML, Horn MC, Cook DR, McNulty BF, Foster VJ: Clinical pharmacology of mivacurium chloride (BW B1090U) in children during nitrous oxide-halothane and nitrous oxide-narcotic anesthesia. Anesth Analg 68:116-121, 1989.

15. Davis PJ, Stiller RL, Cook DR, Brandom BW, Davis JE, Scierka AM: Effects of cholestatic hepatic disease and chronic renal failure on alfentanil pharmacokinetics in children. Anesth Analg 68:579-583, 1989.

16. Cook DR, Stiller RL, Weakly JN, Chakravorti S, Brandom BW, Welch RM: In vitro metabolism of mivacurium chloride (BW B1090U) and succinylcholine. Anesth Analg 68:452-456, 1989.

17. Brandom BW, Woelfel SK, Cook DR, Weber S, Powers DM, Sarner JB, Weakly JN: Comparison of mivacurium chloride (BW B1090U) and suxamethonium chloride administered by bolus and infusion during nitrous oxide-oxygen-opioid anesthesia. Br J Anaesth 62:488-493, 1989.

18. Law SC, Ramzan IM, Brandom BW, Cook DR: Intravenous ranitidine antagonizes intense atracurium-induced neuromuscular blockade in rats. Anesth Analg 69:611-613, 1989.

19. Tullock WC, Diana P, Cook DR, Wilks DH, Brandom BW, Stiller RL, Beach CA: Neuromuscular and cardiovascular effects of high-dose vecuronium. Anesth Analg 70:86-90, 1990.

20. Boston JR, Davis PJ, Brandom BW, Roeber CM: Rate of change of somatosensory evoked potentials in newborn piglets. Anesth Analg 70:275-283, 1990.

21. Brandom BW, Sarner JB, Woelfel SK, Dong ML, Horn MC, Borland LM, Cook DR, Foster VJ, McNulty BF, Weakly JN: Mivacurium chloride (BW B1090U) infusion requirements in pediatric surgical patients during nitrous oxide-halothane and nitrous oxide-narcotic anesthesia. Anesth Analg 71:16-22, 1990.

22. Sarner JB, Brandom BW, Dong ML, Pickle D, Cook DR, Weinberger MJ: Clinical pharmacology of pipecuronium in infants and children during halothane anesthesia. Anesth Analg 71:362-366, 1990.

23. Woelfel SK, Dong ML, Brandom BW, Sarner JB, Cook DR: Vecuronium infusion requirements in children during halothane-narcotic-nitrous oxide, isoflurane-narcotic-nitrous oxide, and narcotic-nitrous oxide anesthesia. Anesth Analg 73:33-38, 1991.

24. Kosko JR, Brandom BW, Chan KH: Masseter spasm and malignant hyperthermia: A retrospective review of a hospital-based pediatric otolaryngology practice.
Int J Pediatr Otorhinolaryngol 23:45-50, 1992.

25. Blinn A, Woelfel SK, Cook DR, Brandom BW, Cohen IT: Pancuronium dose-response revisited. Paediatric Anaesthesia 2:153-155, 1992.

26. Powers DM, Brandom BW, Cook DR, Byers R, Sarner JB, Simpson K, Weber S, Woelfel SK, Foster VJ: Mivacurium infusion during nitrous oxide-isoflurane anesthesia: a comparison with nitrous oxide-opioid anesthesia. Journal of Clinical Anesthesia 4:123-126, 1992.

27. D'Angelo R, Cohen IT, Brandom BW: Continuous epidural infusion of bupivacaine and fentanyl for erythromelalgia in an adolescent. (Case Report) Anesth Analg 74:142-144, 1992.

28. Woelfel SK, Brandom BW, Cook DR, Sarner JB: Effects of bolus administration of ORG-9426 in children during nitrous oxide-halothane anesthesia. Anesthesiology 76:939-942, 1992.

29. Brandom BW, Meretoja OA, Taivainen T, Wirtavuori K: Accelerated onset and delayed recovery of neuromuscular block induced by mivacurium preceded by pancuronium in children. Anesth Analg 76:998-1003, 1993.

30. Meretoja OA, Brandom BW, Taivainen T, Jalkanen L: Synergism between atracurium and vecuronium in children. Br J Anaesth 71:440-442, 1993.

31. Woelfel SK, Brandom BW, McGowan FX, Cook DR: Clinical pharmacology of mivacurium in pediatric patients less than two years old during nitrous oxide-halothane anesthesia. Anesth Analg 77:713-720, 1993.

32. Woelfel SK, Brandom BW, McGowan Jr. FX, Gronert BJ, Cook DR: Neuromuscular effects of a bolus of 600 µg.kg-1 of rocuronium in infants during nitrous oxide-halothane anaesthesia. Paediatric Anaesthesia 4:173-177, 1994.

33. Meretoja OA, Taivainen T, Brandom BW, Wirtavuori K: Frequency of train-of-four stimulation influences neuromuscular response. Br J Anaesth 72:686-687, 1994.

34. Jalkanen L, Meretoja OA, Taivainen T, Brandom BW, Dayal B: Synergism between atracurium and mivacurium compared with that between vecuronium and mivacurium. Anesth Analg 79:998-1002, 1994.

35. Theroux MC , Brandom BW, Zagnoev M, Kettrick RG, Miller F, Ponce C: Dose response of succinylcholine at the adductor pollicis of children with cerebral palsy during propofol and nitrous oxide anesthesia. Anesth Analg 79:761-765, 1994.

36. Brandom BW, Taiwo OO, Woelfel SK, Schon H, Gronert BJ, Cook DR: Spontaneous Versus Edrophonium-Induced Recovery from Paralysis with Mivacurium. Anesth Analg 82: 999-1002, 1996.

37. Brandom BW, Yellon RF, Lloyd ME, Gronert BJ, Theroux M, Simhi E, Chakravorti S , Venkataraman S, Dohar JE, Shapiro AM, Rimmel FL, Reilly J. Recovery from Doxacurium Infusion Administered to Produce Immobility for More Than Four Days in Pediatric Patients in the Intensive Care Unit. Anesthesia Analgesia, in press, 1997.

38. Simhi E, Brandom BW, Lloyd ME, Woelfel SK: Administration of atropine and onset of neuromuscular block produced by atracurium in infants. Pediatric Anaesthesia, in press, 1997.

Reviews, Invited Published Papers, Proceedings of Conference and Symposia, Monographs, Books and Book Chapters.

Reviews:

1. Brandom BW, Cook DR: The clinical use of muscle relaxants in infants and children. In: Current Reviews in Clinical Anesthesia, Volume 4, Miami, Florida, 1984.

2. Brandom BW, Cook DR: Muscle relaxants in children. In: Seminars in Anesthesia, Vol IV, edited by Katz R, Grunne and Stratton, Inc., New York, 4:41-51, 1985.

3. Brandom BW: Neuromuscular blocking drugs in infants and children. Current Opinion in Anesthesiology, 1:24-30, 1988.

4. Brandom BW: New developments in pediatric anesthesia: Neuromuscular blocking drugs. Anesthesiology Clinics of North America, edited by Lerman J, C.V. Mosby Co., St. Louis, MO, 9:781-800, December 1991.

5. Law SC, Brandom BW: Monitoring neuromuscular function in the pediatric patient. In: International Anesthesiology Clinics, Anesthesia Equipment for Infants and Children, edited by Pullerits J and Holzman R, Little Brown and Co., Boston, MA, 30(3):147-162, 1992.

6. Brandom BW, Davis PJ: Changes in drug requirements during growth. Current Opinion in Anaesthesiology 5:374-379, 1992.

7. Brandom BW: New neuromuscular blocking drugs in anesthetized pediatric patients. Current Reviews in Clinical Anesthesia 12 (Lesson 26):8/13/92.

8. Woelfel SK, Brandom BW: Neuromuscular blocking drugs in pediatric anesthesia. Seminars in Anesthesia 11(4):286-291, 1992.

9. Brandom BW: Neuromuscular blocking drugs in pediatric anesthesia. Seminars in Anesthesia 14(1):16-25, 1995.

Invited Published Papers:

1. Brandom BW: The effects of atracurium and succinylcholine on the masseter. (Editorial) Can J Anaesth 37:7-11, 1990.

Letters:

1. Brandom BW, Cook DR. Dose response relationship to mivacurium in humans. Anesthesiology 70:1036-7, 1989.

2. Brandom BW, Meretoja OA. Dose response calculations revisited. (Comment on: Anesth Analg 1993;77:164-7.) Anesth Analg 78:608-9, 1994.

3. Brandom BW, Westman HR: The effects of 0.86 mg/kg of cisatracurium in an infant. Anesthesiology 85:688-9, 1996.

Proceedings:

1. Brandom BW, Brandom RB: A microcomputer based model of anesthetic uptake and distribution. Modeling and Simulation 11:295-300, 1980. Proceedings of the Eleventh Annual Pittsburgh Conference.

2. Tung AS, Brandom BW: 4-aminopyridine reversal of morphine analgesia in aminopyridines and similarly acting drugs: Effects on nerves, muscles, and synapses. Proceedings of the IUPHAR Satellite Symposium, 8th International Congress of Pharmacology, Pans, France, July 27-29, 1981. Advances in the Biosciences 35:233, editors Lechat P, Thesleff S, Bowman WC. Pergamon Press, 1982.

3. Brandom BW, Cook, DR, Stiller RL: Pharmacokinetics of atracurium in infants and children. Readings in Anesthesiology: Neuromuscular Blocking Agents. Presented as a syllabus for a symposium sponsored by Burroughs Wellcome Co. and the University of Pittsburgh School of Medicine, Department of Anesthesiology, 1985.

Book Chapters:

1. Brandom BW, Cook DR: Muscle relaxants in children. In: Muscle Relaxants, ed. Katz R, Grune & Stratton, Inc., New York, NY, Chapter 14, pp. 215-232, 1985.

2. Brandom BW, Carroll JC, Rosenberg H: Malignant hyperthermia. In: Smith's Anesthesia for Infants and Children, Fifth Edition, eds. Motoyama EK and Davis PJ, C.V. Mosby Co., St. Louis, MO, Chapter 29, pp. 759-777, 1989.

3. Brandom BW: Is there a place for infusion of muscle relaxants in clinical anesthesia? In: Problems in Anesthesia: Neuromuscular Relaxants, ed. Rupp SM, J.B. Lippincott Co., Philadelphia, PA, Vol. 3, No. 3, pp. 421-435, 1989.

4 Cook DR, Brandom BW: Pain control with general and local anesthetics. In: Human Pharmacology, Molecular to Clinical, eds. Wingard LB and Brody TM,
C.V. Mosby Co., St. Louis, MO, Chapter 30, 1991.

5. Brandom BW: Malignant hyperthermia and neurolept syndromes. In: Pediatric Critical Care, eds. Fuhrman BP and Zimmerman JJ, C.V. Mosby Co., St. Louis, MO, December, 1991.

6. Brandom BW: Masseter spasm. In: Common Problems in Pediatric Anesthesia, 2nd Edition, ed. Stehling L, C.V. Mosby Co., St. Louis, MO, Chapter 49, pp. 337-342, 1992.

7. Woelfel SK, Brandom BW: Anesthesia for the pediatric ophthalmology patient. In: Duane's Clinical Ophthalmology, eds. Tasman W and Jaeger EA,
J.B. Lippincott, Philadelphia, PA, 6(81):1-17, 1993.

8. Gronert BJ, Brandom BW: Neuromuscular blocking drugs in infants and children. In: Pediatr Clin North Am, ed. Wetzel RC, W.B. Saunders, Philadelphia, 41(1):73-91, 1994.

9. Brandom BW, Gronert GA: Malignant hyperthermia. In: Smith's Anesthesia for Infants and Children Sixth Edition, eds. Motoyama EK and Davis PJ, Mosby-Year Book, St. Louis, Chapter 27, pp. 809-826, 1996.

Published Abstracts.

1. Motoyama EK, Brandom BW, Mestad PM, Walczak SA: Esophageal pressure monitoring in infants. Anesthesiology Vol 53, No. 3, September 1980.

2. Brandom BW, Lin M, Tung AS: 4-aminopyridine reversal of ketamine anesthesia. The Pharmacologist Vol. 23, No. 3, 1981.

3. Tung AS, Brandom BW, Figallo EM: 4-aminopyridine reversal of ketamine anesthesia and morphine analgesia. Anesthesiology 55:A240, September 1981.

4. Tung AS, Brandom BW: 4-aminopyridine reversal of morphine analgesia. Abstracts of the Society for Neuroscience 11th Annual Meeting, p. 798. October 1981.

5. Cook DR, Brandom BW, Rudd D: Clinical pharmacology of atracurium (BW33A) in pediatric patients. Anesthesiology 57:A415, 1982.

6. Brandom BW, Woelfel SK, Cook DR, Fehr B, Rudd D: Relative potency of atracurium in children during halothane, isoflurane or thiopental-fentanyl anesthesia. Anesthesiology 59:A442, 1983.

7. Brandom BW, Woelfel SK, Cook DR, Fehr B, Rudd D: Clinical pharmacology of atracurium in infants. Anesthesiology 59:A440, 1983.

8. Cook DR, Brandom BW, Woelfel SK, Fehr B, Rudd D: Atracurium infusion in children during fentanyl, halothane and isoflurane anesthesia. Anesth Analg 63:201, 1984.

9. Cook DR, Brandom BW, Stiller RL, Woelfel S, Lai A, Slater J: Pharmacokinetics of atracurium in normal and liver failure patients. Anesthesiology 61:A433, 1984.

10. Brandom BW, Weber S, Cook DR, Powers D, Woelfel SK, Marquez J, Weakly JN: Comparison of the effects of BW B1090U and succinylcholine administered by bolus and infusion in anesthetized patients. Anesthesiology 65:A288, 1986.

11. Cook DR, Stiller RL, Chakravorti S, Welch RM, Brandom BW: In vitro metabolism of BW B1090U. Anesthesiology 67:A610, 1987.

12. Sarner JB, Brandom BW, Woelfel SK, Horn M, Cook DR, Dong ML, Davis PJ, Foster VJ, McNulty BF: Neuromuscular effects of BW A938U in anesthetized children. Anesthesiology 67:A365, 1987.

13. Powers D, Weber S, Brandom BW, Byers R, Simpson K, Sarner J, Woelfel SK, Cook DR, McNulty BF, Foster VJ: BW B1090U infusion requirements in adults during isoflurane or narcotic anesthesia. Anesthesiology 67:A359, 1987.

14. Weber S, Brandom BW, Powers D, Sarner JB, Woelfel SK, Cook DR, Foster VJ, Weakly JN: Relative potency of BW B1909U during isoflurane or thiopental-fentanyl anesthesia. Anesthesiology 67:A356, 1987.

15. Tullock WC, Diana P, Cook DR, Wilks DH, Brandom BW, Beach CA: High dose vecuronium: Onset and duration. Anesth Analg 67:S235, 1988.

16. Woelfel SK, Brandom BW, Sarner JB, Horn M, Dong ML, Cook DR, Davis PJ, Foster VJ, McNulty BF: Potency of mivacurium chloride (BW B1090U) during halothane-nitrous oxide anesthesia in children. Anesth Analg 67:S261, 1988.

17. Brandom BW, Sarner JB, Dong ML, Horn M, Woelfel SK, Cook DR, Borland LM, Davis PJ, Foster VJ, McNulty BF: Mivacurium chloride (BW B1090U) infusion requirements in children during halothane or narcotic anesthesia. Anesth Analg 67:S20, 1988.

18. Sarner JB, Brandom BW, Woelfel SK, Dong ML, Horn M, Cook DR, Foster VJ, McNulty BF: Potency of mivacurium chloride (BW B1090U) during narcotic-nitrous oxide anesthesia in children. Anesthesiology 69:A522, 1988.

19. Woelfel SK, Brandom BW, Cook DR, Whitehead B, Borland L: Relationship between the time to beginning of recovery after the initial bolus of muscle relaxant and the infusion rate requirements for mivacurium and succinylcholine. Anesthesiology 69:A521, 1988.

20. Brandom BW, Sarner JB, Dong ML, Woelfel SK, Horn M, Cook DR, Foster VJ, McNulty BF: Plasma concentrations of mivacurium chloride during infusion administration in children anesthetized with halothane-nitrous oxide or narcotic-nitrous oxide. Anesth Analg 68:S38, 1989.

21. Kusakawa I, Brandom BW, Motoyama E, Deneault LG, Ochiai R, Lutz JW: Comparison of spontaneous inspiratory muscle activities and train-of-four tibialis anterior response with low dose atracurium in the cat. Anesthesiology 71:A1110, 1989.

22. Dong ML, Woelfel SK, Brandom BW, Sarner JB, Cook DR: Vecuronium infusion requirements in children during halothane-N2O, isoflurane-N2O, and fentanyl-N2O anesthesia. Anesthesiology 71:A1039, 1989.

23. Boston JR, Davis P, Brandom BW, Roeber C: Similarity in time-related changes of somatosensory evoked potentials and isoflurane. Anesthesiology 71:A398, 1989.

24. Sarner JB, Brandom BW, Dong ML, Pickle D, Weinberger M, Cook DR: The cumulative dose-response relationship of pipecuronium bromide (Arduan) in infants and children. Anesthesiology 71:A778, 1989.

25. Theroux MC, Brandom BW, Cook DR: Neuromuscular monitoring of the flexor hallucis brevis compared with the adductor pollicis in anesthetized children. Anesth Analg 70:S408, 1990.

26. Brandom BW, Georgiu E, Cook DR: Effects of vecuronium on the flexor hallucis brevis compared with the adductor pollicis in anesthetized children. Anesthesiology 73:A1112, 1990.

27. Brandom BW, Stiller RL, Cook DR, Scierka AM: Differential rate of recovery of neuromuscular function in the adductor pollicis and the flexor hallucis after vecuronium. Anesthesiology 73:A1113, 1990.

28. Tullock WC, Wilks DH, Brandom BW, Diana P, Cook DR: ORG9426 single dose-response, onset, and duration with halothane anesthesia. Anesthesiology 73:A877, 1990.

29. Woelfel SK, Brandom BW, Sarner JB, Cook DR, Cyran JA: Dose-response of ORG-9426 in children during nitrous oxide-halothane anesthesia. Anesth Analg 72:S326, 1991.

30. Brandom BW, Woelfel SK, Sarner JB, Cook DR: ORG 9426 infusion requirements in children during halothane anesthesia. Anesthesiology 75:A1072, 1991.

31. Tullock WC, Wilks DH, Brandom BW, Cook DR: ORG 9426: onset, intubation conditions and clinical duration. Anesthesiology 75:A789, 1991.

32. Woelfel SK, Brandom BW, McGowan FX, Cook DR: Dose-response relationships of mivacurium chloride (Mivacron) in infants during nitrous oxide-halothane anesthesia. Anesthesiology 75:A775, 1991.

33. Woelfel SK, Brandom BW, McGowan FX, Cook DR: Stability of Datex neuromuscular monitoring in anesthetized infants. Anesth Analg 74:S352, 1992.

34. Powers D, Lefebvre D, Knos G, Cyran J, Brandom BW: Intubation Conditions After Administration of ORG 9426 During Nitrous Oxide-Fentanyl-Midazolam Anesthesia. Anesth Analg 74:S240, 1992.

35. Cook DR, Chakravorti S, Brandom BW, Stiller RL: Effects of Neostigmine, Edrophonium and Succinylcholine on the in vitro Metabolism of Mivacurium: Clinical Correlates. Anesthesiology 77:A948, 1992.

36. Woelfel SK, Brandom BW, McGowan FX, Cook DR: Plasma Cholinesterase Activity and Response to Mivacurium in Infants. Anesthesiology 77:A966, 1992.

37. Powers D, Lefebvre D, Knos G, Cyran J, Brandom B: Intubation Conditions After Administration of ORG-9426 During Nitrous Oxide-Fentanyl-Midazolam Anesthesia. Anesth Analg 74:S240, 1992.

38. Brandom BW, Meretoja OA, Taivainen T, Wirtavuori K: A Small Dose of Pancuronium Preceding Paralysis Induced by Mivacurium. Anesth Analg 76:S27, 1993.

39. Meretoja OA, Brandom BW, Wirtavuori K, Taivainen T: Neuromuscular Effects of a Combination of Atracurium and Vecuronium in Equipotent Ratio. Anesth Analg 76:S260, 1993.

40. Woelfel SK, Gronert BJ, Brandom BW, McGowan FX, Cook DR: Effects of ORG-9426 in Infants During Halothane Anesthesia. Anesth Analg 76:S467, 1993.

41 Brandom BW, Cook DR, Chakravorti S, Stiller RL: Effects of Pancuronium and Vecuronium on the in vitro Metabolism of Mivacurium, Succinylcholine and Propionylthiocholine. Anesthesiology 79:A949, 1993.

42. Theroux M, Brandom B, Zagnoev M, Kettrick R: Dose Response of Succinylcholine in Anesthetized Children with Cerebral Palsy. Anesthesiology 79:A1125, 1993.

43. Theroux MC, Zagnoev M, Brandom BW, Drago LA: Comparison of Rapid Endotracheal Intubations Using Succinylcholine, Mivacurium and Vecuronium to Combinations of Mivacurium and Vecuronium. Anesth Analg 78:S436, 1994.

44. Simhi E, Brandom BW, Gronert BJ, Woelfel SK: Timing of Intubation in Children After 300 mg/kg Mivacurium. Anesthesiology 83:A902, 1995.

45. Taiwo OO, Woelfel SK, Brandom BW, Schoen HE, Gronert BJ, Cook DR: Spontaneous vs Edrophonium Induced Recovery From Paralysis with Mivacurium. Anesthesiology 83:A900, 1995.

46. Brandom BW, Woelfel SK, Gronert BJ, Cook DR, Ference A, Dayal B: Effects of 51W89 (Cistracurium) in Children during Halothane Nitrous Oxide Anesthesia. Anesthesiology 83:A921, 1995.

47. Brandom BW, Gronert BJ, Woelfel SK, Cook DR: Lack of Synergy Between Mivacurium and Doxacurium or Pipecuronium. Anesth Analg 82:S46, 1996.

48. Brandom BW, Gronert BJ, Yellon RF, Lloyd ME, Shapiro AM, Rimmel FL: Doxacurium Infusion Given For More Than Five Days In The Intensive Care Unit. Anesth Analg 82:S47, 1996.

49. Brandom BW, Meretoja OA, Gronert BJ, Woelfel SK, Cook DR: Synergy Between Mivacurium and Pancuronium. Anesth Analg 82:S48, 1996.

50. Simhi E, Brandom BW, Gronert BJ, Woelfel SK: Intubation Scale For Children. Anesth Analg 82:S412, 1996.

51. Tarbell SE, Brandom BW, Davis PJ, Kosmach B: Chronic Pain in Childhood: Add Munchausen by Proxy to the Differential Diagnosis. 8th World congress on Pain, 1996.

52. Simhi E, Cook DR, Brandom BW, Lloyd ME, Chakravorti S, Kuntz R. Pharmacokinetics of Mivacurium in anesthetized Pediatric Patients undergoing Elective Surgery. Anesthesiology 85:A1061, 1996.

53. Brandom BW, Meretoja OA, Simhi E, Taivainen T, Wolfe S, Woelfel SK, Gronert BJ, Cook DR: Effects of Mivacurium 0.3 mg/kg in pediatric surgical patients during nitrous oxide-halothane compared with nitrous oxide-opioid anesthesia. Anesth Analg 84:S???1997.

54. Brandom BW, Lloyd ME, Woelfel SK, Simhi E, Landsman IS. Comparison of the Datex Electromyograph and Paragraph Monitors During Recovery from Pancuronium in Anesthestized Children. Anesth Analg 84:S???1997.

55. Simhi E, Brandom BW, Lloyd ME, Woelfel SK: Administration of atropine and onset of neuromuscular block produced by atracurium in infants. Anesth Analg 84:S???1997.

TEACHING:

I supervise student nurses, anesthesiology residents and fellows in pediatric anesthesiology during clinical care of all types of pediatric patients in the operating room at Children's Hospital. This accounts for about 60% of my working hours.

As part of the education of our house staff, I present 30 minute to 60 minute discussions on several areas in pediatric anesthesia. This lecture schedule is repeated every three months. My participation includes the following topics:

Inhalation Anesthetics in Pediatric Patients

Neuromuscular Blocking Agents in Pediatric Anesthesia

Thermoregulation

Malignant Hyperthermia

Retinopathy of Prematurity

Neuromuscular Diseases

Neuromuscular Monitoring in the Operating Room

Management of the Pediatric Trauma Patient

As part of our extended program for senior residents I have presented discussions on the design of clinical studies. Included are such topics as sample size calculations, contrasting results of analysis of variance and regression analysis, an example of time dependent logistic regression, examples of meta-analysis, and the predictive value of a test.

I frequently give 45-60 minute lectures at regional and national meetings of anesthesiologists and CRNAs on similar topics. Since 1986 the titles of these lectures have included:

The Use of Muscle Relaxants in Pediatric Anesthesia

New Neuromuscular Blocking Drugs

Anesthetic Management of Pediatric Trauma Patients

Inhalation Anesthetics in Pediatric Anesthesia

Intravenous Inductions in Pediatric Anesthesia

Pediatric Anesthesia for Recovery Room Nurses

Muscle Relaxants Administered by Infusion

The Pediatric Patient: Pharmacodynamic and Pharmacokinetic Considerations
in Anesthetic Management

Factors Affecting Termination of Neuromuscular Block

Succinylcholine Should Not Be Used in Pediatric Anesthesia

Outpatient Pediatric Anesthesia

Pain in the Neonate

Legal and Ethical Issues in Pediatric Drug Research

The Use of Neuromuscular Blocking Drugs in Patients with Excretory Failure

Masseter Spasm

For several years, I contributed to the basic pharmacology course for second year medical students with two lectures on the Pharmacology of Inhalation Anesthetics and the Kinetics of Inhalation Anesthetics. In September 1994 and 1995 I again contributed an hour long lecture with notes on the subject of general anesthesia to the second year medical student course in neurobiology.

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RESEARCH:

1. Grants Received Years Inclusive Grant Number and Title Source

1982 Efficacy and safety of atracurium in children and adolescents.

Burroughs Wellcome Company, $22,495 Cook DR, Brandom BW, Woelfel SK

1983-1984 Blood-brain permeability to morphine in neonatal piglets.

NIH-BRSG (HRC:CHP), $6,000 Brandom BW, Schieber RA, Cook DR

1983-1984 Safety and efficacy of atracurium in infant surgical patients under N2O/O2/halothane anesthesia. Burroughs Wellcome Company, $4,500 Cook DR, Brandom BW, Woelfel SK

1984 Kinetics of atracurium in children. Burroughs Wellcome Company, $7,200 Cook DR, Brandom BW, Woelfel SK, Stiller RL

1984 Efficacy and safety of atracurium infusions in pediatric surgical patients under N2O/O2 narcotic or halothane or isoflurane anesthesia. Burroughs Wellcome Company, $13,500 Cook DR, Brandom BW, Woelfel SK

1985 Comparison of succinylcholine and BW B1090U by infusion. Burroughs Wellcome Company, $18,000 Cook DR, Brandom BW, Weber S

1986-1987 Safety and efficacy of BW B1090U in adults. Burroughs Wellcome Company, $75,000 Cook DR, Brandom BW, Weber S, Powers DM

1986 In vivo degradation of BW B1090U and succinylcholine. Burroughs Wellcome Company, $25,000 Cook DR, Stiller RL, Brandom BW

1986-1987 Safety and efficacy of vecuronium at high doses. Organon Pharmaceutical, $36,000 Cook DR, Brandom BW, Stiller RL, Tullock WC

1987 Safety and efficacy of BW A938U in children. Burroughs Wellcome Company, $20,000 Brandom BW, Cook DR, Sarner JB, Woelfel SK

1987-1988 Safety and efficacy of BW B1090U in children. Burroughs Wellcome Company, $36,000 Brandom BW, Cook DR, Woelfel SK, Sarner JB

1988-1989 Determination of the cumulative dose-response of pipecuronium bromide in pediatric patients under halothane anesthesia. Organon Inc., $18,000 Brandom BW, Sarner JB, Dong ML

1990 A study of the safety and efficacy of ORG-9426 in pediatric surgical patients during nitrous oxide-oxygen-halothane anesthesia. AKZO, $27,000 Brandom BW, Woelfel SK, Sarner JB, Cook DR

1990 A study of the safety and efficacy of mivacurium (BW B1090U) in pediatric surgical patients during nitrous oxide-oxygen-halothane anesthesia. Burroughs Wellcome Co., $69,300 Brandom BW, Woelfel SK, McGowan FX, Cook DR

1991 A continuation of the study of the safety and efficacy of ORG-9426 in pediatric surgical patients during nitrous oxide-oxygen-halothane anesthesia. AKZO, $21,000 Brandom BW, Woelfel SK, McGowan FX, Cook DR

1993 A study of the safety and efficacy of BW 51W89 in pediatric surgical patients during nitrous oxide-oxygen-halothane anesthesia. Burroughs Wellcome Co, $33,660 Brandom BW, Woefel SK, Gronert BJ, Cook DR.

1994 Applied to the study of long-term infusion of doxacurium. Nonspecific support from Burroughs Wellcome Co., $1,000 Brandom BW.

1995 Effects of mivacurium 300 mcg/kg in pediatric surgical patients during nitrous oxide-oxygen-halothane or nitrous oxide-oxygen-narcotic anesthesia. Burroughs Wellcome Co., $75,140

Brandom BW, Woelfel SK, Gronert BJ, Simhi E.

1995 The use of neuromuscular blockers in the ICU.
Glaxo Wellcome Inc., $1,500 Brandom BW.

1996 A study of the safety and efficacy of ORG-9487 in pediatric surgical patients during nitrous oxide-oxygen-halothane anesthesia. AKZO, $55,965 Brandom BW, Simhi E, Woelfel SK, Lloyd M, Fertal K.

1996 Pharmacokinetics of doxacurium in pediatric patients undergoing laryngotracheoplasty and postoperative mechanical ventilation with cisatracurium administered during elimination of doxacurium. Glaxo Wellcome Inc., $6,076.37 Brandom BW, Woelfel SK, Lloyd M, Yellon RF, Venkataraman ST, Dohar JE, Post JC.

1997 An evaluation of the safety and efficacy of cisatracurium (Nimbex) for tracheal intubation in pediatric surgical patients during N2O/O2/halothane or N2O/O2/opioid anesthesia. Glaxo Wellcome Inc., Brandom BW, Woefel SK, Cook DR, Morillo-Dellerme J.

2. Seminars and Invited Lectureships Related to Your Research:

April 1980 Brandom BW, Brandom RB, Cook DR: A mathematical model for predicting uptake and distribution in inhalation anesthetics in infants and children. This was presented in abstract form at the 1980 American Academy of Pediatrics, Section on Anesthesiology, April 1980, and at the 11th Annual Modeling and Simulation Conference at the University of Pittsburgh School of Engineering.

April 1980 Cook DR, Brandom BW, Shiu G: Brain halothane levels and halothane EDI50 in infant rats. Abstract presented at the 1980 American Academy of Pediatrics, Section on Anesthesiology meeting in Las Vegas, NV.

Oct. 14-16, 1980 Brandom BW: The microcomputer based model of inhalation anesthetic uptake and distribution was presented as a scientific exhibit at the American Society of Anesthesiologists meeting in
St. Louis, MO.

Oct. 17, 1980 Brandom BW: An abbreviated discussion of the microcomputer based model of inhalation anesthetic uptake was delivered to the Microcomputers in Anesthesia conference in Iowa City, IO.

April 16, 1983 Brandom BW, Cook DR: Neuromuscular and cardiovascular effects of atracurium, gallamine, and pancuronium in pediatric patients during nitrous oxide- halothane anesthesia. Abstract presented at the American Academy of Pediatrics meeting, Philadelphia, PA.

April 13, 1985 Brandom BW, Cook DR, Stiller RL: Pharmacokinetics of atracurium in infants and children. Abstract presented at the American Academy of Pediatrics, Atlanta, GA.

April 30, 1987 Brandom BW: Preliminary Data on BW A938U and BW B1090U. Abstract presented at the Third International Conference on Muscle Relaxants, Palm Springs, CA.

March 10, 1989 Theroux MC, Brandom BW: Neuromuscular monitoring of the flexor hallucis brevis versus the adductor pollicis in anesthetized children. Abstract presented at the American Academy of Pediatrics meeting, Orlando, FL.

March 10, 1989 Brandom BW: The effects of fluids on nausea and vomiting in pediatric strabismus surgery patients. Abstract presented at the American Academy of Pediatrics meeting, Orlando, FL.

March 17, 1991 Brandom BW, Woelfel SK, Sarner JB, Cook DR, Cyran JA: Dose-response of ORG-9426 in children during nitrous oxide-halothane anesthesia. Abstract presented at the American Academy of Pediatrics Meeting, San Diego, CA.

March 17, 1991 Blinn A, Woelfel SK, Cook DR, Brandom BW, Cohen IT: Pancuronium dose-response revisited. Abstract presented at the American Academy of Pediatrics Meeting, San Diego, CA.

April 10-12, 1992 Brandom BW, Woelfel SK, McGowan FX, Gronert BJ, Cook DR: The effects of an "intubating dose" of ORG-9426 (Rocuronium) in children under N2O-O2-halothane anesthesia. Abstract presented at the American Academy of Pediatrics Meeting, New York, NY.

May 25, 1992 Brandom BW, Woelfel SK, McGowan FX, Gronert BJ, Cook DR: Effects of ORG 9426 600 mcg/kg in infants and children. Abstract presented at the 4th International Neuromuscular Symposium, Montreal, Quebec, Canada.

May 25, 1992 Brandom BW: Plasma cholinesterase activity and response to mivacurium in infants. Abstract presented at the 4th International Neuromuscular Symposium, Montreal, Quebec, Canada.

April 23-25, 1994 Dayal B, Brandom BW, Woelfel SK, Gronert BJ, Cook DR,
Ference A: 51W89 in Children During Halothane Nitrous Oxide Anesthesia. Abstract presented at the American Academy of Pediatrics Section on Anesthesiology Program for Scientific Sessions, Denver, CO.

April 23-25, 1994 Gronert BJ, Meretoja OA, Brandom BW, Woelfel SK, Cook DR: Synergism Between Pancuronium and Mivacurium. Abstract presented at the American Academy of Pediatrics Section on Anesthesiology Program for Scientific Sessions, Denver, CO.

Feb. 17-19, 1995 Taiwo OO, Woelfel SK, Brandom BW, Schoen HE, Gronert BJ.

Cook DR: Spontaneous vs. Edrophonium Induced Recovery From Paralysis with Mivacurium. Abstract presented at the 1st joint winter meeting of the Society for Pediatric Anesthesia and American Academy of Pediatrics Section on Anesthesiology, Phoenix, AZ.

Feb. 16-18, 1996 Effects of mivacurium 300 mcg/kg in pediatric surgical patients during nitrous oxide-oxygen-halothane or nitrous oxide-oxygen-narcotic anesthesia. Brandom BW, Meretoja OA, Simhi E, Taivainen T, Wolfe S, Woelfel SK, Gronert BJ, Cook DR. Abstract presented at the 2nd joint winter meeting of the Society for Pediatric Anesthesia and American Academy of Pediatrics Section on Anesthesiology, Tampa, Florida.

Feb. 16-18, 1996 Comparison of the Datex Electromyograph and Paragraph Monitors During Recovery from Pancuronium in Anesthestized Children. Brandom BW, Lloyd ME, Woelfel SK, Simhi E, Landsman IS. Abstract presented at the 2nd joint winter meeting of the Society for Pediatric Anesthesia and American Academy of Pediatrics Section on Anesthesiology, Tampa, Florida.

3. Other Research Related Activities

Continuing NON Medical Education

9/1991-1996 Completed course work for a Master's Degree in Biostatistics at the Graduate School of Public Health of the University of Pittsburgh

Sabbatical Activities

May to July 1992 Visitor at the Children's Hospital of Helsinki, Finland with

Dr. Olli Meretoja, the chief of Anesthesiology/ICU at that hospital.

Extradepartmental Lectures (from 1990):

Feb. 6, 1990 Pain Response in the Neonate. Anesthesiology Grand Rounds, Wilmington General Hospital, Wilmington, DE.

May 19, 1990 Controversies in the Use of Relaxants in Pediatric Patients.
The Third Annual Symposium on the State of the Art in Muscle Relaxants, Atlantic City, NJ.

May 29, 1990 Neuromuscular Blocking Drugs in Pediatric Anesthesia and Current Questions in the Administration of Intravenous Fluids to Pediatric Patients. Annual Review Course in Anesthesia, McGill University, Montreal, Quebec, Canada.

Aug. 2, 1990 Neuromuscular Blocking Drugs in Pediatric Anesthesia. Department of Anesthesiology, University of California at Davis, Davis, CA

Nov. 29, 1990 Anesthesia for Pediatric Outpatients. St. Vincent Charity Hospital, Cleveland, OH

Jan. 14, 1991 Malignant Hyperthermia. Trauma Conference, Children's Hospital of Pittsburgh, Pittsburgh, PA.

April 8, 1991 Neuromuscular Blocking Drugs in Infants and Children; Fluid Management in Pediatric Patients: Special Considerations. Pediatric Trauma, Miami Comprehensive Review Course,
Miami, FL.

May 13 & 14, 1991 Neuromuscular Blocking Drugs and Management of the Pediatric

Trauma Patient. University of Illinois in Chicago and Michael Reese Hospital, Chicago, IL.

May 18, 1991 Advances in Pediatric Anesthesia: Matching the New Anesthetics with the New Relaxants. The 4th Annual Symposium on the State of the Art in Muscle Relaxants, Atlantic City, NJ.

Oct. 29, 1991 Pediatric Clinical Forum. American Society of Anesthesiologists Meeting, San Francisco, CA.

Nov. 1991 Anesthetic Management of Pediatric Trauma Patients. Southern Medical Association, Atlanta, GA.

Jan. 13, 1992 Neuromuscular Blocking Drugs in Pediatric Anesthesia.

Medical College of Virginia, Richmond, VA.

Oct. 16, 1992 Age-related Differences in Response to Neuromuscular Blocking Drugs. Society for Pediatric Anesthesia Meeting, New Orleans, LA.

Nov. 1992 Controversies in the Use of Neuromuscular Blocking Drugs in Pediatric Anesthesia. Akron, OH.

Nov. 1992 Controversies in the Use of Neuromuscular Blocking Drugs in Pediatric Anesthesia. Children's Hospital of Detroit,
Detroit, MI.

Dec. 11, 1992 New Neuromuscular Blocking Drugs. Anesthesia Symposium,

University of Helsinki, Helsinki, Finland.

Feb. 8, 1993 Controversies in the Use of Neuromuscular Blocking Drugs. Grand Rounds, Vanderbilt University, Nashville, TN.

April 8, 1993 Controversies in the Use of Neuromuscular Blocking Drugs in Pediatric Anesthesia. St. John's Hospital, Health East Pediatric Anesthesia Symposium, Minneapolis, MN.

April 10, 1994 Reversal of Neuromuscular Block. University of Pittsburgh Anesthesia Update and CDQ Exam Review Course, Pittsburgh, PA.

May 18, 1994 Will Rocuronium Replace Succinylcholine? Sixth Annual Review of Neuromuscular Blocking Drugs, Atlantic City, NJ.

June 4, 1994 Some Serious Anesthesia Complications: Controversies in the Use of Succinylcholine. Regional Meeting of Malignant Hyperthermia Association of the United States (MHAUS), Pittsburgh, PA.

June 15, 1994 Neuromuscular Blocking Drugs (3 controversial ones) in Pediatric Anesthesia. Maricopa County Hospital, University of Arizona, Phoenix, AZ.

Sept. 20, 1994 Mivacurium, A Neuromuscular Blocker for Use in Anesthetized Adults and Children. Hamot Medical Center, Anesthesiology Department, Erie, PA.

Oct. 7, 1994 Recent Publications Regarding Neuromuscular Blocking Drugs: Succinylcholine, Mivacurium, Rocuronium. Children's Hospital of Philadelphia, Anesthesiology Grand Rounds, Philadelphia, PA.

Oct. 8, 1994 Problems in Experimental Design and Analysis of Clinical Studies in Pediatric Anesthesiology. The First Delaware Valley Pediatric Anesthesiology Consortium meeting, A.I. DuPont Institute, Wilmington, DE.

Oct. 16, 1994 Anesthesia for Gastrointestinal Emergencies in the Neonate and Infant. Fairview General Hospital, Cleveland, OH.

Dec. 13, 1994 Succinylcholine and the FDA, part of Relaxants in the 1990's: New Standards New Controversies. 48th Post Graduate Assembly of the New York State Society of Anesthesiologists, New York, NY.

Jan. 10, 1995 Reversal of Neuromuscular Block. Department of Anesthesiology, Boston Children's Hospital, Boston, MA.

Jan. 11, 1995 Neuromuscular Blocking Drugs in Pediatric Anesthesia. Department of Anesthesiology, University of Massachusetts, Worcester, MA.

May 3, 1995 Neuromuscular Blocking Drugs in Pediatric Anesthesia. Department of Anesthesiology, Medical Center of Central Massachusetts, Worcester, MA.

May 7, 1995 Complications of Succinylcholine. 7th Annual Symposium on the State of the Art in Muscle Relaxants, Atlantic City, NJ.

June 8, 1995 Reversal of Neuromuscular Block. Department of Anesthesiology, University of California at Davis, Davis, California.

June 8, 1995 Neuromuscular Blocking Drugs in Pediatric Anesthesia. Sacramento, California.

Oct. 22, 1995 Muscle Relaxants in Infants and Children-How they differ from adults. ASA Refresher Course, Atlanta, Georgia.

Nov. 14, 1995 Intravenous inductions in Pediatric Anesthesia, Augusta, Georgia

Nov. 15, 1995 Neuromuscular Blocking Drugs in Pediatric Anesthesia. Department of Anesthesiology, Medical College of Georgia, Augusta, Georgia.

Nov. 16, 1995 Management of Pediatric Trauma. Department of Anesthesiology, Medical College of Georgia, Augusta, Georgia.

March 6, 1996 Intravenous Induction Techniques in Pediatric Anesthesia, and Special Considerations in Pediatric Trauma, Tenth Annual Miami Comprehensive Review Course, Miami, FL.

April 17, 1996 Muscle Relaxants in Infants and Children-How they differ from adults. London, Ontario.

April 18, 1996 Neuromuscular Blocking Drugs in Pediatric Anesthesia. Toronto Academy of Medicine, Anesthesiology Section.

September 5, 1996 Neuromuscular Blockers and the ICU: What Do We Know? 5th Annual Pediatric Technology Conference of the Pediatric Pharmacy Advocacy Group, Inc. Scottsdale, Arizona.

November 16, 1996 Post Obstructive Pulmonary Edema,

November 17, 1996 Post Operative Management of Infants after Laryngotracheal Reconstruction, at the Third International Symposium on the Pediatric Airway, Orlando, Florida

SERVICE:

University and Medical School: Occasional instructor of medical students in the operating room and the anesthesia simulation lab.

Hospital / Departmental:

1980-Present University Health Center of Pittsburgh, Children's Hospital: Coordinator of records and pre-op planning for patients susceptible to malignant hyperthermia. Assistance of L. Borland and J. Greenberg with computerization of records.

1984-85 Scientific Affairs Committee, Children's Hospital representative

1988-Present to Departmental Committee.

1985-86 Liason to tricyclic antidepressant studies at Western Pennsylvania Psychiatric Institute for facilitation of intravenous studies.

1987-1991 Acting Chief in absence of Dr. Cook, Children's Hospital.

1989-Present Disaster Preparedness Committee, Children's Hospital.

1989-1991 Internal coordinator of CA3 teaching program at Children's Hospital, 1989-1991.

1990-Present Pharmacy and Therapeutics Committee, Children's Hospital.
Member of subcommittee on sedation guidelines.

Chair of the Committee as of January 1996.

Fall 1994 Service Standards Committee Member, Children's Hospital.

Fall 1995 Chair, Committee on Issues of Discrimination, Department of Anesthesiology.

National:

1986-1988 Committee on Pediatric Anesthesia of the American Society of Anesthesiologists, Meeting.

1988-1990 Member, Executive Committee (Drugs), Anesthesiology Section, American Academy of Pediatrics.

1989 Reviewed articles for The Journal of Pediatrics and Pediatric Pulmonology

1989-1991 Member, Executive Committee of the Anesthesiology Section of the American Academy of Pediatrics

1989-1992 Board of Directors, Society for Pediatric Anesthesia

1990-1991 Committee on Pediatric Anesthesia of the American Society of Anesthesiologists, Clinical

1991-1992 Sub-Committee on Pediatric Anesthesia for the American Society of Anesthesiologists, annual meeting

1991-present Reviewer for Anesthesia and Analgesia

1991-present MHAUS Hotline Consultant

1992-1994 Member, Society for Pediatric Anesthesia, Committee on Research.

1992-present Reviewer for Journal of Clinical Anesthesia

1993-present Reviewer for Paediatric Anaesthesia

1993-1994 ASA Sub-Committee on Neuromuscular Transmission, Adjunct Member

1994 Reviewer for American Journal of Hospital Pharmacy

1994-present Reviewer for American Journal of Anesthesiology

1995-1996 ASA Committee on Pediatric Anesthesia

1996 Reviewer for American Journal of Health-System Pharmacy

March 1996 Moderator at the Society for Pediatric Anesthesia/Anesthesia Section of the American Academy of Pedatrics annual meeting.

October 1996 Facilitator of a Pediatric Anesthesia Section and of a Neuromuscular Section of abstract presentations.

Papers in review:

1. Yellon RF, Parameswaran M, Brandom BW. Decreasing morbidity following laryngotracheal reconstruction in children.

2. Brandom BW: Malignant Hyperthermia and Neurolept Syndromes. In editorial review for next edition of Pediatric Critical Care, ed. Fuhrman BP.

3. Tarbell SE, Brandom BW, Davis PJ, Kosmach B: Factitious disorder by proxy as an etiology for chronic pain in chilhood. In review at J Pain and Symptom Management.

4. Brandom BW, Meretoja OA, Simhi E, et al. Effects of mivacurium 0.3 mg/kg in pediatric surgical patients during nitrous oxide-halothane compared with nitrous oxide-opioid anesthesia. In review, 1996.

(updated December, 1996)