Department of Environmental and Occupational Health

Committees Grants Honors & Awards Memberships Papers & Reviews Presentations Publications Research

Bruce R. Pitt - Publications

Refereed Articles - Last 5 years

  1. Kagan VE, Bayır HA, Belikova NA, Kapralov O, Tyurina YY, Tyurin VA, Jiang J, Stoyanovsky DA, Wipf P, Kochanek PM, Greenberger JS, Pitt B, Shvedova AA, Borisenko G.  Cytochrome c/cardiolipin relations in mitochondria: A kiss of death.  Free Radic Biol Med. 2009 Mar 11. PMID: 19285551

  2. Tyurin VA, Tyurina YY, Jung MY, Tungekar MA, Wasserloos KJ, Bayir H, Greenberger JS, Kochanek PM, Shvedova AA, Pitt B, Kagan VE. Mass-spectrometric analysis of hydroperoxy- and hydroxy-derivatives of cardiolipin and phosphatidylserine in cells and tissues induced by pro-apoptotic and pro-inflammatory stimuli. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Mar 13. PMID: 19328050

  3. Garner AL, St. Croix CM, Pitt, BR, Leikauf GD, Ando S and Koide K. Specific Fluorogenic Probes for Ozone in Biological and Atmospheric Samples. Nature Chem Biol 2009 (in press).

  4. Phillippi JA, Eskay MA, Pitt BR, Kubala BS, and Gleason TG. Reduced oxidative stress in the ascending aorta of bicuspid aortic valve patients: impact on the extracellular matrix. J. Thor Cardiovasc Surg.  Pending revisions

  5. Kagan VE, Wipf P, Stoyanovsky D, Greenberger JS, Borisenko G, Belikova NA, Yanamala N, Samhan Arias AK, Tungekar MA, Jiang J, Tyurina YY, Ji J, Klein-Seetharaman J, Pitt BR, Shvedova AA, Bayır H. Mitochondrial targeting of electron scavenging antioxidants: Regulation of selective oxidation vs random chain reactions. Adv Drug Deliv Rev. 2009 Aug 27. PMID: 1971639

  6. Li, J., Wilson, A., Gao, X., Kuruba R., Liu, Y., Poloyac, S., Pitt, B., Xie, W. and Li, S. Coordinated regulation of dimethlyarginine dimethlyaminohydrolase-1 and cationic amino acid transporter-1 by farnesoid X receptor in mouse liver and kidney and its implication in the control of blood levels of asymmetric dimethylarginine. J Pharmacol Exp Ther (in press).

  7. Polk, A.A., Maul, T.M., KcKeel, D.T., Snyder, T.A., Lehocky, C.A., Pitt, B., Beer-Stolz, D., Federspiel, W.J. and Wagner, W.R. A biohybrid artificial lung prototype with active mixing of endothelialized microporous hollow fibers. Bioengineer and Biotech. In press.

  8. Tyurina YY, Tyurin VA. Kaynar M., Kapralova VI, Wasserloos K, Li J, Mosher M, Wright L, Wipf, P, Watkins S, Pitt BR, and Kagan VE. Oxidative lipidomics of hyperoxic acute lung injury:Mass-spectrometric characterization of cardiolipin and phosphatidylserine peroxidation. Am. J. Physiol: Lung Cell Mol Physiol. 2010 Jul;299(1):L73-85. Epub 2010 Apr 23. PMID: 20418384

  9. Szczepaniak WS, Pitt BR and McVerry BJ. S1P2 receptor dependent Rho-kinase activation mediates vasoconstriction in the pulmonary circulation induced by sphingosine 1-phosphate. Am. J. Physiol: Lung Cell Mol Physiol. 2010 Jul;299(1):L137-45. Epub 2010 Apr 30. PMID: 20435688

  10. Li H, Su X, Yan X, Wasserloos K, Chao W, Kaynar AM, Liu ZQ, Leikauf GD, Pitt BR, Zhang LM. Toll-like Receptor 4-Myeloid Differentiation Factor 88 Signaling Contributes to Ventilator-induced Lung Injury in Mice. Anesthesiology. 2010 Jul 29. PMID: 20683250

  11. Li H, Cao R, Wasserloos KJ, Bernal P, Liu ZQ, Pitt BR, St Croix CM. Nitric oxide and zinc homeostasis in pulmonary endothelium. Ann N Y Acad Sci. 2010 Aug;1203:73-8. PubMed PMID: 20716286

  12. John E, Laskow TC, Buchser WJ, Pitt BR, Basse PH, Butterfield LH, Kalinski P, Lotze MT. Zinc in innate and adaptive tumor immunity. J Transl Med. 2010 Nov 18;8:118. PMID: 21087493

  13. Phillippi JA, Eskay MA, Kubala AA, Pitt BR, Gleason TG. Altered oxidative stress responses and increased type I collagen expression in bicuspid aortic valve patients. Ann Thorac Surg. 2010 Dec;90(6):1893-8. PMID: 21095332

  14. Li HH, Xu J, Wasserloos KJ, Li J, Tyurina YY, Kagan VE, Wang X, Chen AF, Liu ZQ, Stoyanovsky D, Pitt BR, Zhang LM. Cytoprotective effects of Albumin, Nitrosated or Reduced, in Cultured Rat Pulmonary Vascular Cells. Am J Physiol Lung Cell Mol Physiol. 2011 Jan 14. PMID: 21239532

  15. Thambiayya K, Wasserloos KJ, Huang Z, Kagan VE, St Croix CM, Pitt BR. LPS-induced decrease in intracellular labile zinc [Zni] contributes to apoptosis in cultured sheep pulmonary artery endothelial cells (SPAEC). Am J Physiol Lung Cell Mol Physiol. 2011 Jan 14. PMID: 21239534

  16. Tyurina YY, Tyurin VA, Kapralova VI, Wasserloos K, Mosher M, Epperly MW, Greenberger JS, Pitt BR, Kagan VE. Oxidative lipidomics of ϒ-radiation-induced lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation. Radiat Res. 2011 May;175(5):610-21. Epub 2011 Feb 21. PMID:21338246

  17. Bernal PJ, Bauer EM, Cao R, Maniar S, Mosher M, Chen J, Wang QJ, Glorioso JC, Pitt BR, Watkins SC, St Croix CM. A Role for Zinc in Regulating Hypoxia-Induced Contractile Events in Pulmonary Endothelium. Am J Physiol Lung Cell Mol Physiol. 2011 Mar 4. PMID: 21378023

  18. Cambal LK, Swanson MR, Yuan Q, Weitz AC, Li HH, Pitt B, Peterson J, Pearce LL. Acute, Sub-lethal Cyanide Poisoning in Mice is Ameliorated by Nitrite Alone: Complications Arising from Concomitant Administration of Nitrite and Thiosulfate as an Antidotal Combination. Chem Res Toxicol. 2011 Jul 18;24(7):1104-12. Epub 2011 May 11. PMID:21534623

  19. Pitt BR, Christman JW, Gunst SJ, Matthay MA, Stevens T, Ware LB. Physiology, reductionism, and translational medicine: the right mix. Am J Physiol Lung Cell Mol Physiol. 2011 Oct;301(4):L389-90. Epub 2011 Aug 19. No abstract available. PMID:21856812

  20. Atkinson J, Kapralov AA, Yanamala N, Tyurina YY, Amoscato AA, Pearce L, Peterson J, Huang Z, Jiang J, Samhan-Arias AK, Maeda A, Feng W, Wasserloos K, Belikova NA, Tyurin VA, Wang H, Fletcher J, Wang Y, Vlasova II, Klein-Seetharaman J, Stoyanovsky DA, Bayr H, Pitt BR, Epperly MW, Greenberger JS, Kagan VE. A mitochondria-targeted inhibitor of cytochrome c peroxidase mitigates radiation-induced death. Nat Commun. 2011 Oct 11;2:497. doi: 10.1038/ncomms1499. PubMed PMID: 21988913

  21. Gorbunov NV, Atkins JL, Gurusamy N, Pitt BR. Iron-induced remodeling in cultured rat pulmonary artery endothelial cells. Biometals. 2012 Feb;25(1):203-17. Epub 2011 Nov 17. PMID:22089858

  22. Thambiayya K, Wasserloos KJ, Kagan VE, Stoyanovsky D, Pitt BR. A critical role for increased labile zinc in reducing sensitivity of cultured sheep pulmonary artery endothelial cells to LPS-induced apoptosis. Am J Physiol Lung Cell Mol Physiol. 2012 Apr 20. PMID: 22523284

  23. Cioffi DL, Wu S, Chen H, Alexeyev M, St Croix CM, Pitt BR, Uhlig S, Stevens T. Orai1 Determines Calcium Selectivity of an Endogenous TRPC Heterotetramer Channel. Circ Res. 2012 Apr 24. PMID: 22534489

  24. Sparavero LJ, Amoscato AA, Dixon CE, Long JB, Kochanek PM, Pitt BR, Bayir H and Kagan VE. Mapping of phospholipids by MALDI imaging (MALDI-MS): realities and expectations. Chem Phys Lipids 165: 545-562, 2012  PMID 22692104

  25. Li HH, Li Q, Liu P, Liu YY, Li J, Wasserloos K, Chao W, You M, Oury TD, Chkinder S, Hackham DJ, Billiar TR, Leikauf GD, Pitt BR and Zhang LM. WNT1 inducible signaling pathway protein 1 (WISP1) contributes to ventilator induced lung injury.  Am J Resp Cell Mol Biol 47: 528-535, 2012 PMID: 22700866

  26. Darwiche SS, Pfeifer R, Menzel C, Ruan X, Hoffman M, Cai C, Chanthaphavong RS, Loughran P, Pitt BR, Hoffman R, Paper HC and Billiar TR. Inducible inducible nitric oxide synthase contributes to immune dysfunction following trauma. Shock 38: 499-507, 2012,  PMID  23042189

  27. Chen, J, Winarski, KL, Myerburg, MM,  Pitt, BR and Sheng S. Probing the Structural Basis of Zn2+ Regulation of the Epithelial Na+ Channel. J. Biol. Chem. 287: 35589-98, 2012. PMID  22930753

  28. Lee SM, McLaughlin JN, Frederick DR, Zhu L, Thambiayya K, Wasserloos KJ, Kaminski I, Pearce L, Peterson J, Li J, Latoche JD, Peck-Palmer O, Beer-Stolz D, Fattman CL, Alcorn JF, Oury TD, Angus DC, Pitt BR, Kaynar AM. Metallothionein-induced zinc partitioning exacerbates hyperoxic acute lung injuryAm J Physiol Lung Cell Mol Physiol. 304: L350-L360, PMID23275622