Refereed Articles - Last 5 years

1. Pitt, BR and Ortiz, LA. Stem cells in lung biology. Am. J. Physiol. Lung Cell Mol. Physiol. 286: L1621-1623, 2004. PMID: 15003931
   
   
2. Ma, Z, Li, J, Yang L, Mu Y, Xie W, Pitt, B and Li S. Inhibition of LPS- and CpG DNA induced TNF- a response by oxidized phospholipids. Am.J.Physiol:Lung Cell Mol Physiol. 286: L808-L816, 2004. PMID: 14644758
   
   
3. Li, J., Ma Z, Tang ZL, Stevens T, Pitt B and Li S. CpG DNA-mediated immune response in pulmonary endothelial cells. Am. J. Physiol: Lung Cell Mol Physiol. 287: L552-L558, 2004. PMID: 15155271
   
   
4. St. Croix, CM, Stitt, MS, Leelavanichkul, K, Wasserloos, KJ, Pitt, BR and Watkins, SC. Nitric oxide mediated signaling in endothelial cells as determined by spectral fluorescence resonance energy transfer. Free Radical Biology Medicine 15: 785-792, 2004. Abstract
   
   
5. Tyurina YY, Tyurin VA, Zhao Q, Djukic M, Quinn PJ, Pitt BR and Kagan VE. Oxidation of phosphotidylserine: a mechanism for plasma membrane phospholipids scrambling during apoptotis? Biochem Biophys Res Comm 324: 1059-1064, 2004. PMID: 15485662
   
   
6. Gandley, R, Han W, Hubel CA, Pitt BR and Kagan VE. S-nitroso-albumin mediated relaxation is enhanced by ascorbate and copper: effects in pregnancy and preeclampsia plasma. Hypertension 45: 21-27, 2005. PMID: 15569857
   
   
7. St. Croix, CM, Leelavinchkul K, Watkins SC, Kagan VE and Pitt BR. Nitric oxide and zinc home ostasis in acute lung injury. Proc.Amer.Thor Soc. 2: 236-242, 2005. PMID: 16222044
   
   
8. Ma Z, Li J, He F, Wilson A, Reynolds PR, Pitt B and Li S. SiRNA mediated sensitization to microbial components. Biochem Biophys Res Comm. 330: 755-759, 2005.
9. Wilson A, Zhou W, Alber S, Tang Z-L, Kennel S, Watkins S, Huang L, Pitt B and Li S. Targeted delivery of oligonucleotides to pulmonary endothelium. Mol Ther 12: 510-518, 2005. PMID: 15953766
   
   
10. Wilson A, He F, Li J, Ma Z, Pitt B and Li S. Targeted delivery of therapeutic oligonucleotides to pulmonary circulation. Adv Genetics 54: 21-41, 2005. PMID: 16096006
    
    
11. Stoyanovsky DA, Tyurina YY, Tyurin VA, Anand, D, Mandavia DN, Gius D, Ivanova J, Pitt C, Billiar TR and Kagan VE., Pitt BR and Kagan VE. Thioredoxin and lipoic acid catalyze the denitrosation of low molecular weight and protein S-nitrosothiols. J. Am. Chem. Soc. 127: 15815-15823, 2005. PMID: 16277524
    
    
12. He, F, Li J, Mu Y, Ma Z, Wilson, A, Alber S, Stevens T, Watkins S, Pitt B, Xie W, and Li S. Down regulation of endothelin-1 by farnesoid X receptor in vascular endothelial cells. Circulation Research 98: 192-199, 2006. PMID: 16357303
    
    
13. Stitt MS, Wasserloos KJ, Tang Z, Liu X, Pitt BR and St. Croix CM. Nitric oxide induced nuclear translocation of the metal responsive transcription factor, MTF-1, is me diated by zinc release from metallothionein. Vascular Pharmacology 44: 149-155, 2006. PMID: 16423564
    
    
14. Zhang LM, St. Croix CM, Cao R, Wasserloos K, Watkins SC, Stevens T, Li S, Tyurin V, Kagan VE and Pitt BR. Cell-surface protein disulfide isomerase is required for transnitrosation of metallothionein by S-nitroso-albumin in intact rat pulmonary vascular endothelial cells. Exp. Biol. Med. Exp. Biol. Med. 231: 1507-1515, 2006. PMID: 17018873
    
    
15. Tyurina YY, Basova LV, Knoduru NV, Tyurin VA, Potapovich AI, Cai P, Bayir H, Stoyanovsky D, Pitt BR, Shvedova AA, Fadeel B and Kagan VE. Nitrosative stress inhibits the aminophospholipid translocase resulting in phosphatidylserine externalizationand macrophage engulfment: implications for the resolution of inflammation. J. Biol. Chem 282: 8498-8509, 2007. PMID: 17229723
    
    
16. Li J, Wilson A, Kuruba R, Zhang Q, Gao X, He F, Zhang LM, Pitt BR, Xie W, Li S. FXR-mediated regulation of eNOS expression in vascular endothelial cells. Cardiovasc Res. 2007 Oct 19; [Epub ahead of print]. PMID: 18006476
    
    
17. Zhang Q, He F, Kuruba R, Gao X, Wilson A, Li J, Billiar TR, Pitt BR, Xie W, Li S. FXR-Mediated Regulation of Angiotensin Type 2 Receptor Expression in Vascular Smooth Muscle Cells. Cardiovasc Res. 2007 Nov 13; [Epub ahead of print]. PMID: 1800643
    
    
18. Fattman CL, Gambelli F, Hoyle GW, Pitt BR, Ortiz LA. Epithelial expression of TIMP1 does not alter sensitivity to bleomycin-induced lung injury in C57BL/6 mice. Am J Physiol Lung Cell Mol Physiol. 2008 Jan 4; [Epub ahead of print] PMID: 18178676
19. Kleinschmidt AM, Nassiri M, Stitt MS, Wasserloos K, Watkins SC, Pitt BR, Jahroudi N. Sequences in intron 51 of the von Willebrand factor gene target promoter activation to a subset of lung endothelial cells in transgenic mice. J Biol Chem. 2008 Feb 1; 283 ( 5 ): 2741-50. Epub 2007 Nov 28. PMID: 18048367 [PubMed - in process]
    
    
20. Kaynar AM, Houghton AM, Lum EH, Pitt BR, Shapiro SD. Neutrophil Elastase Is Needed for Neutrophil Emigration into Lungs in Ventilator-Induced Lung Injury. Am J Respir Cell Mol Biol. 2008 Feb 14; [Epub ahead of print] PMID: 18276796
    
    
21. Bernal PJ, Leelavanichkul K, Bauer E, Cao R, Wilson A, Wasserloos KJ, Watkins SC, Pitt BR, St Croix CM. Nitric oxide mediated zinc release contributes to hypoxic regulation of pulmonary vascular tone.Circ Res. 2008 May 15. PMID: 18483408
    
    
22. Nemec AA, Leikauf G, Pitt BR, Wasserloos KJ, Barchowsky A.   Nickel Mobilizes Intracellular Zinc to Induce Metallothionein in Human Airway Epithelial Cells.  Am J Respir Cell Mol Biol. 2008 Dec 18; [Epub ahead of print].  PMID: 19097988
    
    
23. Kagan VE, Bayır HA, Belikova NA, Kapralov O, Tyurina YY, Tyurin VA, Jiang J, Stoyanovsky DA, Wipf P, Kochanek PM, Greenberger JS, Pitt B, Shvedova AA, Borisenko G.  Cytochrome c/cardiolipin relations in mitochondria: A kiss of death.  Free Radic Biol Med. 2009 Mar 11. [Epub ahead of print] PMID: 19285551
    
    
24. Tyurin VA, Tyurina YY, Jung MY, Tungekar MA, Wasserloos KJ, Bayir H, Greenberger JS, Kochanek PM, Shvedova AA, Pitt B, Kagan VE. Mass-spectrometric analysis of hydroperoxy- and hydroxy-derivatives of cardiolipin and phosphatidylserine in cells and tissues induced by pro-apoptotic and pro-inflammatory stimuli. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Mar 13. [Epub ahead of print] PMID: 19328050
    
    
25. Garner AL, St. Croix CM, Pitt, BR, Leikauf GD, Ando S and Koide K. Specific Fluorogenic Probes for Ozone in Biological and Atmospheric Samples. Nature Chem Biol 2009 (in press).
    
    
26. Phillippi JA, Eskay MA, Pitt BR, Kubala BS, and Gleason TG. Reduced oxidative stress in the ascending aorta of bicuspid aortic valve patients: impact on the extracellular matrix. J. Thor Cardiovasc Surg.  Pending revisions
    
    
27. Kagan VE, Wipf P, Stoyanovsky D, Greenberger JS, Borisenko G, Belikova NA, Yanamala N, Samhan Arias AK, Tungekar MA, Jiang J, Tyurina YY, Ji J, Klein-Seetharaman J, Pitt BR, Shvedova AA, Bayır H. Mitochondrial targeting of electron scavenging antioxidants: Regulation of selective oxidation vs random chain reactions. Adv Drug Deliv Rev. 2009 Aug 27. [Epub ahead of print] PMID: 19716396