Refereed Articles - Last 5 years

1. Tyurina YY, Basova LV, Knoduru NV, Tyurin VA, Potapovich AI, Cai P, Bayir H, Stoyanovsky D, Pitt BR, Shvedova AA, Fadeel B and Kagan VE. Nitrosative stress inhibits the aminophospholipid translocase resulting in phosphatidylserine externalizationand macrophage engulfment: implications for the resolution of inflammation. J. Biol. Chem 282: 8498-8509, 2007. PMID: 17229723
   
   
2. Li J, Wilson A, Kuruba R, Zhang Q, Gao X, He F, Zhang LM, Pitt BR, Xie W, Li S. FXR-mediated regulation of eNOS expression in vascular endothelial cells. Cardiovasc Res. 2007 Oct 19. PMID: 18006476
   
   
3. Zhang Q, He F, Kuruba R, Gao X, Wilson A, Li J, Billiar TR, Pitt BR, Xie W, Li S. FXR-Mediated Regulation of Angiotensin Type 2 Receptor Expression in Vascular Smooth Muscle Cells. Cardiovasc Res. 2007 Nov 13. PMID: 1800643
   
   
4. Fattman CL, Gambelli F, Hoyle GW, Pitt BR, Ortiz LA. Epithelial expression of TIMP1 does not alter sensitivity to bleomycin-induced lung injury in C57BL/6 mice. Am J Physiol Lung Cell Mol Physiol. 2008 Jan 4; PMID: 18178676
   
   
5. Kleinschmidt AM, Nassiri M, Stitt MS, Wasserloos K, Watkins SC, Pitt BR, Jahroudi N. Sequences in intron 51 of the von Willebrand factor gene target promoter activation to a subset of lung endothelial cells in transgenic mice. J Biol Chem. 2008 Feb 1; 283 ( 5 ): 2741-50. Epub 2007 Nov 28. PMID: 18048367
   
   
6. Kaynar AM, Houghton AM, Lum EH, Pitt BR, Shapiro SD. Neutrophil Elastase Is Needed for Neutrophil Emigration into Lungs in Ventilator-Induced Lung Injury. Am J Respir Cell Mol Biol. 2008 Feb 14; PMID: 18276796
   
   
7. Bernal PJ, Leelavanichkul K, Bauer E, Cao R, Wilson A, Wasserloos KJ, Watkins SC, Pitt BR, St Croix CM. Nitric oxide mediated zinc release contributes to hypoxic regulation of pulmonary vascular tone.Circ Res. 2008 May 15. PMID: 18483408
   
   
8. Nemec AA, Leikauf G, Pitt BR, Wasserloos KJ, Barchowsky A.   Nickel Mobilizes Intracellular Zinc to Induce Metallothionein in Human Airway Epithelial Cells.  Am J Respir Cell Mol Biol. 2008 Dec 18.  PMID: 19097988
   
   
9. Kagan VE, Bayır HA, Belikova NA, Kapralov O, Tyurina YY, Tyurin VA, Jiang J, Stoyanovsky DA, Wipf P, Kochanek PM, Greenberger JS, Pitt B, Shvedova AA, Borisenko G.  Cytochrome c/cardiolipin relations in mitochondria: A kiss of death.  Free Radic Biol Med. 2009 Mar 11. PMID: 19285551
   
   
10. Tyurin VA, Tyurina YY, Jung MY, Tungekar MA, Wasserloos KJ, Bayir H, Greenberger JS, Kochanek PM, Shvedova AA, Pitt B, Kagan VE. Mass-spectrometric analysis of hydroperoxy- and hydroxy-derivatives of cardiolipin and phosphatidylserine in cells and tissues induced by pro-apoptotic and pro-inflammatory stimuli. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Mar 13. PMID: 19328050
    
    
11. Garner AL, St. Croix CM, Pitt, BR, Leikauf GD, Ando S and Koide K. Specific Fluorogenic Probes for Ozone in Biological and Atmospheric Samples. Nature Chem Biol 2009 (in press).
    
    
12. Phillippi JA, Eskay MA, Pitt BR, Kubala BS, and Gleason TG. Reduced oxidative stress in the ascending aorta of bicuspid aortic valve patients: impact on the extracellular matrix. J. Thor Cardiovasc Surg.  Pending revisions
    
    
13. Kagan VE, Wipf P, Stoyanovsky D, Greenberger JS, Borisenko G, Belikova NA, Yanamala N, Samhan Arias AK, Tungekar MA, Jiang J, Tyurina YY, Ji J, Klein-Seetharaman J, Pitt BR, Shvedova AA, Bayır H. Mitochondrial targeting of electron scavenging antioxidants: Regulation of selective oxidation vs random chain reactions. Adv Drug Deliv Rev. 2009 Aug 27. PMID: 1971639
    
    
14. Li, J., Wilson, A., Gao, X., Kuruba R., Liu, Y., Poloyac, S., Pitt, B., Xie, W. and Li, S. Coordinated regulation of dimethlyarginine dimethlyaminohydrolase-1 and cationic amino acid transporter-1 by farnesoid X receptor in mouse liver and kidney and its implication in the control of blood levels of asymmetric dimethylarginine. J Pharmacol Exp Ther (in press).
    
    
15. Polk, A.A., Maul, T.M., KcKeel, D.T., Snyder, T.A., Lehocky, C.A., Pitt, B., Beer-Stolz, D., Federspiel, W.J. and Wagner, W.R. A biohybrid artificial lung prototype with active mixing of endothelialized microporous hollow fibers. Bioengineer and Biotech. In press.
    
    
16. Tyurina YY, Tyurin VA. Kaynar M., Kapralova VI, Wasserloos K, Li J, Mosher M, Wright L, Wipf, P, Watkins S, Pitt BR, and Kagan VE. Oxidative lipidomics of hyperoxic acute lung injury:Mass-spectrometric characterization of cardiolipin and phosphatidylserine peroxidation. Am. J. Physiol: Lung Cell Mol Physiol. 2010 Jul;299(1):L73-85. Epub 2010 Apr 23. PMID: 20418384
    
    
17. Szczepaniak WS, Pitt BR and McVerry BJ. S1P2 receptor dependent Rho-kinase activation mediates vasoconstriction in the pulmonary circulation induced by sphingosine 1-phosphate. Am. J. Physiol: Lung Cell Mol Physiol. 2010 Jul;299(1):L137-45. Epub 2010 Apr 30. PMID: 20435688
    
    
18. Li H, Su X, Yan X, Wasserloos K, Chao W, Kaynar AM, Liu ZQ, Leikauf GD, Pitt BR, Zhang LM. Toll-like Receptor 4-Myeloid Differentiation Factor 88 Signaling Contributes to Ventilator-induced Lung Injury in Mice. Anesthesiology. 2010 Jul 29. PMID: 20683250
    
    
19. Li H, Cao R, Wasserloos KJ, Bernal P, Liu ZQ, Pitt BR, St Croix CM. Nitric oxide and zinc homeostasis in pulmonary endothelium. Ann N Y Acad Sci. 2010 Aug;1203:73-8. PubMed PMID: 20716286
    
    
20. John E, Laskow TC, Buchser WJ, Pitt BR, Basse PH, Butterfield LH, Kalinski P, Lotze MT. Zinc in innate and adaptive tumor immunity. J Transl Med. 2010 Nov 18;8:118. PMID: 21087493
    
    
21. Phillippi JA, Eskay MA, Kubala AA, Pitt BR, Gleason TG. Altered oxidative stress responses and increased type I collagen expression in bicuspid aortic valve patients. Ann Thorac Surg. 2010 Dec;90(6):1893-8. PMID: 21095332
    
    
22. Li HH, Xu J, Wasserloos KJ, Li J, Tyurina YY, Kagan VE, Wang X, Chen AF, Liu ZQ, Stoyanovsky D, Pitt BR, Zhang LM. Cytoprotective effects of Albumin, Nitrosated or Reduced, in Cultured Rat Pulmonary Vascular Cells. Am J Physiol Lung Cell Mol Physiol. 2011 Jan 14. PMID: 21239532
    
    
23. Thambiayya K, Wasserloos KJ, Huang Z, Kagan VE, St Croix CM, Pitt BR. LPS-induced decrease in intracellular labile zinc [Zni] contributes to apoptosis in cultured sheep pulmonary artery endothelial cells (SPAEC). Am J Physiol Lung Cell Mol Physiol. 2011 Jan 14. PMID: 21239534
    
    
24. Tyurina YY, Tyurin VA, Kapralova VI, Wasserloos K, Mosher M, Epperly MW, Greenberger JS, Pitt BR, Kagan VE. Oxidative lipidomics of ϒ-radiation-induced lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation. Radiat Res. 2011 May;175(5):610-21. Epub 2011 Feb 21. PMID:21338246
    
    
25. Bernal PJ, Bauer EM, Cao R, Maniar S, Mosher M, Chen J, Wang QJ, Glorioso JC, Pitt BR, Watkins SC, St Croix CM. A Role for Zinc in Regulating Hypoxia-Induced Contractile Events in Pulmonary Endothelium. Am J Physiol Lung Cell Mol Physiol. 2011 Mar 4. PMID: 21378023
    
    
26. Cambal LK, Swanson MR, Yuan Q, Weitz AC, Li HH, Pitt B, Peterson J, Pearce LL. Acute, Sub-lethal Cyanide Poisoning in Mice is Ameliorated by Nitrite Alone: Complications Arising from Concomitant Administration of Nitrite and Thiosulfate as an Antidotal Combination. Chem Res Toxicol. 2011 Jul 18;24(7):1104-12. Epub 2011 May 11. PMID:21534623
    
    
27. Pitt BR, Christman JW, Gunst SJ, Matthay MA, Stevens T, Ware LB. Physiology, reductionism, and translational medicine: the right mix. Am J Physiol Lung Cell Mol Physiol. 2011 Oct;301(4):L389-90. Epub 2011 Aug 19. No abstract available. PMID:21856812
    
    
28. Atkinson J, Kapralov AA, Yanamala N, Tyurina YY, Amoscato AA, Pearce L, Peterson J, Huang Z, Jiang J, Samhan-Arias AK, Maeda A, Feng W, Wasserloos K, Belikova NA, Tyurin VA, Wang H, Fletcher J, Wang Y, Vlasova II, Klein-Seetharaman J, Stoyanovsky DA, Bayîr H, Pitt BR, Epperly MW, Greenberger JS, Kagan VE. A mitochondria-targeted inhibitor of cytochrome c peroxidase mitigates radiation-induced death. Nat Commun. 2011 Oct 11;2:497. doi: 10.1038/ncomms1499. PubMed PMID: 21988913
    
    
29. Gorbunov NV, Atkins JL, Gurusamy N, Pitt BR. Iron-induced remodeling in cultured rat pulmonary artery endothelial cells. Biometals. 2012 Feb;25(1):203-17. Epub 2011 Nov 17. PMID:22089858
    
    
30. Thambiayya K, Wasserloos KJ, Kagan VE, Stoyanovsky D, Pitt BR. A critical role for increased labile zinc in reducing sensitivity of cultured sheep pulmonary artery endothelial cells to LPS-induced apoptosis. Am J Physiol Lung Cell Mol Physiol. 2012 Apr 20. PMID: 22523284
    
    
31. Cioffi DL, Wu S, Chen H, Alexeyev M, St Croix CM, Pitt BR, Uhlig S, Stevens T. Orai1 Determines Calcium Selectivity of an Endogenous TRPC Heterotetramer Channel. Circ Res. 2012 Apr 24. PMID: 22534489