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The University of Pittsburgh Institutional Review Board Frequently Asked Questions About Cardiac Arrest and the ASPIRE Trial
Useful information about sudden cardiac arrest is available from:
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Welcome to the AutoPulse Assisted Prehospital International Resuscitation (ASPIRE) Trial website for the Pittsburgh Study site. Study OverviewThe AutoPulse Assisted Prehospital International Resuscitation (ASPIRE) Trial compares the efficacy of circulatory assist by manual chest compression versus an automated chest compression device (AutoPulse™) during the resuscitative attempt following out-of-hospital cardiac arrest. The study will enroll approximately 2330 patients over the course of one year, from three to five urban communities, using an approximately 1:1 randomization between control (manual chest compressions) and intervention (chest compressions performed by the AutoPulse device). The primary endpoint is survival to hospital admission, defined as alive four hours after the (911) call to the EMS dispatch center. The study will be monitored by an independent Data and Safety Monitoring Board and is funded by a grant from Revivant Corporation to the University of Washington.
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