Biodegradable polymers e.g. poly(lactic acid), poly(e-caprolactone) are emerging as suitable scaffolds for tissue engineering. Tissue growth strongly depends on adherence of cells to the scaffolds and obtaining required growth factors from the surrounding. Biodegradable polymers lack pendant functional groups, which can be utilized for conjugation of bioactive peptides and proteins. Present synthetic methods to incorporate functional groups in biodegradable polymers are tedious. We are developing novel block copolymers comprising biodegradable and functionally rich biocompatible segments, which can be utilized to conjugate bioactive molecules.