|Did you see
the Part I of this lecture?
When the external voltage source was
turned off the cell resumed its control spontaneous beating rate. The next
line is a continuation of the recording from the same cell. When EPA was
added to the superfusate the beating rate began to slow and now the myocyte
paid no attention to stimuli at 15 V or at 20 V from the external source. At
25 V the cell responds but only to every other stimulus. When delipidated
bovine serum albumin was added to the medium perfusing the myoytes the EPA
was extracted from the myocytes and the beating returned to its control
rate. Now the myocyte responded to external stimuli delivered at 15 V just
as it had initially. This action of the n-3 fatty acids occurring directly
on every cardiomyocyte on the cover-slip in the absence of hormonal or
neural control, indicates the potent electrical stabilizing action of these
interesting n-3 fish oil fatty acids.