Research Summary

			Sharan ramaswamy
			Research Assistant Professor sdr22@pitt.edu 412.235.5188

In general, my research area can be classified under the category of tissue
engineering (TE).  However, within this field, my specific research interests
fall under the following themes:

1) Applications of TE strategies towards cardiovascular and cartilage regeneration
and/or repair.
2) The study of biomechanical and/or biochemical events that aid in engineered
tissue formation.
3) The use of magnetic resonance imaging techniques such as superparamagnetic
iron oxide cellular labeling and the gadolinium exclusion method to monitor cell
migration and the progression of extra-cellular matrix (ECM) constituents
non-invasively.
4) Computational fluid dynamic (CFD) modeling to predict the effects of flow and/or
engineered tissue movement on ECM formation.

At the University of Pittsburgh, I am currently actively working on the following project
goals:

i)  Organ-level heart valve studies to determine the effects of physiological
conditioning on tri-leaflet tissue engineered heart valves.
ii)  CFD models to study the effects of sample movement and/or pulsatility in flow on
valvular tissue development
iii)  The effects of individual or combined mechanical modes of stimuli
(flow, stretch and flexure) on engineered tissue development over long durations
(> 3 weeks) of in-vitro mechanical pre-conditioning regimes.

If you are more interested in my work and/or work history, please refer to my CV which can be found by clicking the link below.

Curriculum Vita

Download as pdf.